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Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Plants and plant-derived preparations as co-treatments for COVID-19

A recent Journal of Medicinal Food study proposed a comprehensive guideline for applying plants and plant-derived formulations to co-treat severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and other viral infections.

8 Sep 2022

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston.

8 Sep 2022

Scientists develop a model human gut microbiome

A team of US-based scientists has developed a novel bacterial community comprising 119 microbial species naturally found in the human body. The study is published in the journal Cell.

7 Sep 2022

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical, a pioneering medical device company based in Singapore, has become the first start-up to win the prestigious WIPO-IPOS IP for Innovation Award for 2022

7 Sep 2022

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical, a pioneering medical device company based in Singapore, has become the first start-up to win the prestigious WIPO-IPOS IP for Innovation Award for 2022. Now in its 10th year, this award celebrates Singaporean companies that have achieved outstanding growth through the successful application of intangible assets and intellectual property.

From Vivo Surgical 7 Sep 2022

The role of nasal microbiome in Parkinson's disease

A recent study provides an overview of how the nasal bacterial population influences olfactory processing and neurodegeneration.

5 Sep 2022

New and unique technique to brain imaging has potential to save lives

Observing the brain without creating any breaks in the skull is an emerging technology for those studying various brain-related diseases.

5 Sep 2022

High-quality human clinical trials needed to determine the benefits of CBD for heart disease patients

As cannabidiol (CBD) use rises, high quality randomized clinical trials are needed to determine if anti-inflammatory benefits of CBD for heart disease seen in preclinical data will work in a real-world setting, according to research presented at ACC Latin America 2022 Together with CardioAcademic.

5 Sep 2022

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Announcing a new article publication from Acta Pharmaceutica Sinica B. Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies.

5 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

Antiviral activity of favipiravir against Zika and SARS-CoV-2 in cynomolgus macaques

A new study determines the antiviral efficacy of favipiravir against ZIKV and SARS-CoV-2 infections.

4 Sep 2022

Researchers demonstrate improved culture of primate induced pluripotent stem cells

The following study transplanted iPSCs derived from two NHP species, chimpanzee and pigtailed macaque, into blastocysts from another NHP species – the rhesus macaque.

1 Sep 2022

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The current study focused on the ability of this nmAb to neutralize Delta, Omicron, and other VOCs, as well as its efficacy when given by the intranasal route in an animal model.

1 Sep 2022

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

Researchers explored the molecular and cellular mechanisms of SARS-CoV-2 infection.

30 Aug 2022

A leather-based in vitro model for determining the effect of cosmetics on skin microbes

A recent study discusses the development of a leather-based in vitro model due to its close resemblance to human skin.

28 Aug 2022

Chinese researchers identify a new molecular mechanism of NASH pathogenesis

Nonalcoholic steatohepatitis (NASH), characterized by liver steatosis, inflammation and injury, has emerged as one of major causes for end-stage liver disease like hepatocellular carcinoma. However, what drives its progression?

25 Aug 2022

Targeting Na+/K+ ATPase alpha 1 proteins could help identify novel therapies for blood clots, thrombosis

Targeting Na+/K+ ATPase alpha 1 (ATP1A1) subunit proteins could help identify novel therapies for addressing blood clots and thrombosis, according to a new study by Marshall University researchers.

24 Aug 2022

in vivo News and Research

Self-replicating intradermal RNA vaccine against SARS-CoV-2

All SARS-CoV-2 variants neutralized by a potent new antibody

Plants and plant-derived preparations as co-treatments for COVID-19

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

Scientists develop a model human gut microbiome

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

Vivo Surgical honored with the esteemed WIPO-IPOS IP for Innovation Award

The role of nasal microbiome in Parkinson's disease

New and unique technique to brain imaging has potential to save lives

High-quality human clinical trials needed to determine the benefits of CBD for heart disease patients

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Antiviral activity of favipiravir against Zika and SARS-CoV-2 in cynomolgus macaques

Researchers demonstrate improved culture of primate induced pluripotent stem cells

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

A leather-based in vitro model for determining the effect of cosmetics on skin microbes

Chinese researchers identify a new molecular mechanism of NASH pathogenesis

Targeting Na+/K+ ATPase alpha 1 proteins could help identify novel therapies for blood clots, thrombosis

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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