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Newborn screening for "bubble-baby" disease boosts survival of children

Screening newborns for severe combined immunodeficiency disease (SCID) significantly increases the survival of children after bone marrow transplantation, a new North American study finds.

21 Jun 2023

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Researchers performed a protein diffusion network analysis using tissue-specific GRNs to identify predispositions to COVID-19.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

Study highlights the role of high cholesterol in SARS-CoV-2 infectivity

A recent study unveiled the doorway that SARS-CoV2 uses to slip inside cells undetected.

20 Jun 2023

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

A study in mice reports a CRISPR/Cas9 gene-editing delivery system, capable of bypassing the blood-brain-barrier and modulating neuronal receptor pathways, to treat chronic anxiety.

20 Jun 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

High lipoprotein(a) levels linked to repeated heart disease events in older adults

Researchers report that high lipoprotein(a) levels were linked to repeated coronary heart disease events in older adults.

18 Jun 2023

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

New research by investigators in Ghent, Belgium shows that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial resistance. The findings are presented at ASM Microbe 2023, the annual meeting of the American Society for Microbiology.

18 Jun 2023

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses.

16 Jun 2023

Combination of two drugs may be more effective in treating resistant breast cancer

Cancer cells are even smarter than scientists previously believed, according to new CU Boulder research.

16 Jun 2023

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Researchers reported on the contribution of trained immune responses to protection against SARS-CoV-2 infections and future pandemics.

16 Jun 2023

Research explores complex relationship between cholesterol and breast cancer risk

Research explores the complex relationship between cholesterol and breast cancer risk, with some studies suggesting an increased risk with elevated cholesterol levels while others find an inverse association.

15 Jun 2023

Study: Some breast cancer drugs may lessen the effect of weight loss medications

Breast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presented Friday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Researchers used aerosolized receptor binding domain (RBD)-62 with 1,000-fold enhanced binding affinity.

15 Jun 2023

What is the impact of maternal SARS-CoV-2 booster vaccination on antibodies in blood and breast milk?

Researchers investigated the impact of maternal COVID-19 vaccination on SARS-CoV-2 antibodies.

15 Jun 2023

Analyzing the role of ACSL4 in quadruple negative breast cancer

A new review paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "ACSL4: biomarker, mediator and target in quadruple negative breast cancer."

15 Jun 2023

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

Study analyzed the impact of SARS-CoV-2 infection on semen quality.

14 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals - from fuels to fabrics and drugs - beyond the normal repertoire of microbes.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Enzyme News and Research

Newborn screening for "bubble-baby" disease boosts survival of children

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Study highlights the role of high cholesterol in SARS-CoV-2 infectivity

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

CBD and THC: promising remedies for aluminum-related neurological damage

High lipoprotein(a) levels linked to repeated heart disease events in older adults

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Combination of two drugs may be more effective in treating resistant breast cancer

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Research explores complex relationship between cholesterol and breast cancer risk

Study: Some breast cancer drugs may lessen the effect of weight loss medications

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

What is the impact of maternal SARS-CoV-2 booster vaccination on antibodies in blood and breast milk?

Analyzing the role of ACSL4 in quadruple negative breast cancer

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

"Homing gene drive system" could help suppress agricultural pests

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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