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Japanese researchers identify genetic quirk linked to severe COVID-19

Despite intensive research since the pandemic began, much remains unknown about COVID-19, particularly why it can be so severe in some cases and relatively mild in others.

25 Jul 2023

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Study aimed to understand the specific needs of lung cancer in never smokers (LCINS) patients.

25 Jul 2023

Researchers uncover the biology behind insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

25 Jul 2023

Using 'click chemistry' to create novel multi-protein anti-cancer agents

A potent anti-cancer therapy has been created using Nobel prize-winning "click chemistry", where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

24 Jul 2023

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University Singapore (NTU Singapore) and Massachusetts Institute of Technology (MIT), have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.

24 Jul 2023

Fly-to-bedside resource offers new hope for COVID-19 treatments

Millions of deaths and ongoing illnesses caused by the COVID-19 pandemic have prompted scientists to seek new ways of understanding how viruses so skillfully enter and reprogram human cells.

21 Jul 2023

Salk researchers uncover molecular mechanisms of HIV drug resistance

Salk Institute researchers, in collaboration with the National Institutes of Health, have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV.

21 Jul 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Researchers investigated whether trypsin, a protease, increased SARS-CoV-2 infectivity.

21 Jul 2023

Researchers identify how enzymes can help prevent heart damage in chemotherapy patients

Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients.

20 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

Sweat-based wearable technologies as a potential monitoring tool for patients with metabolic syndrome

The opportunities and challenges of sweat-based wearables for monitoring metabolic syndrome.

20 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Researchers examine plasma interleukin-6, vascular cell adhesion molecule-1, and C-reactive protein levels in pregnant women with preeclampsia.

20 Jul 2023

Study shows how NSAIDs exacerbate C. difficile infections

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide?

19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

Researchers investigated the effect of SARS-CoV-2 spike (S) protein subunit 1 (S1) on the pulmonary endothelium.

19 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Rice bioengineers receive NIH grant for sickle cell disease research

Rice University bioengineer Gang Bao and his team have won a 4-year, $2.6 million grant from the National Institutes of Health to address critical questions surrounding the safety and efficacy of using gene editing to treat sickle cell disease.

18 Jul 2023

Enzyme News and Research

Japanese researchers identify genetic quirk linked to severe COVID-19

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Researchers uncover the biology behind insulin production

Using 'click chemistry' to create novel multi-protein anti-cancer agents

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Fly-to-bedside resource offers new hope for COVID-19 treatments

Salk researchers uncover molecular mechanisms of HIV drug resistance

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Researchers identify how enzymes can help prevent heart damage in chemotherapy patients

Researchers discover new way to target bacterial cell wall

Sweat-based wearable technologies as a potential monitoring tool for patients with metabolic syndrome

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Study shows how NSAIDs exacerbate C. difficile infections

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Rice bioengineers receive NIH grant for sickle cell disease research

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