Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

Novel approach induces cell death via dual targeting of DNA repair mechanism

Proteins commonly known as BRCA - short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development.

13 Jun 2018

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer.

12 Jun 2018

Researchers identify racial differences in breast cancer immune microenvironment

Roswell Park Comprehensive Cancer Center researchers have identified significant differences in the immune microenvironment of breast cancer tumors between African-American and white women, shedding light on the ways in which race can influence cancer development and outcomes.

4 Jun 2018

Protein inhibitor drug found to be safe and effective in treating patients with acute myeloid leukemia

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia with relapsed or refractory disease.

4 Jun 2018

Study finds increase in lifestyle-related cancers over the past decade

Lifestyle-related cancers, such as lung, colorectal, and skin cancers, have increased globally over the past decade, according to the most comprehensive analysis of cancer-related health outcomes and patterns ever conducted.

4 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

Our immune system's arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system.

30 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

$Study reveals rate of vertebral and non-vertebral fractures in children with leukemia$

Study reveals rate of vertebral and non-vertebral fractures in children with leukemia

In a Journal of Bone and Mineral Research study that followed 186 children with Acute Lymphoblastic Leukemia (ALL) for 6 years after initiation of chemotherapy, approximately 1 in 5 children experienced a non-vertebral fracture and 1 in 3 had a new vertebral fracture.

23 May 2018

Researchers complete genomic map of chronic lymphocytic leukemia

Researchers have created a high-resolution map of the entire epigenome of chronic lymphocytic leukemia, the most common form of leukemia.

23 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris - an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group - is addressing this very question.

22 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia plays a much wider role in the disease than previously thought.

18 May 2018

New treatment regimen boosts survival for young adults and children with T-cell malignancies

In a federally funded, randomized phase III clinical trial performed by the Children's Oncology Group (COG), 90% of children and young adults with T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LL) were alive four years after starting treatment regimens on this trial, and 84% were cancer free.

17 May 2018

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.

17 May 2018

Leukemia News and Research

Further Reading

Novel approach induces cell death via dual targeting of DNA repair mechanism

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Researchers identify racial differences in breast cancer immune microenvironment

Protein inhibitor drug found to be safe and effective in treating patients with acute myeloid leukemia

Study finds increase in lifestyle-related cancers over the past decade

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Study reveals rate of vertebral and non-vertebral fractures in children with leukemia

Researchers complete genomic map of chronic lymphocytic leukemia

Celgene to share new and updated data around novel hematological therapies

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

Scientists identify new potential target to combat acute myeloid leukemia

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

New treatment regimen boosts survival for young adults and children with T-cell malignancies

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Researchers test new cancer research model that may reduce cost and speed up studies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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