Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Study sheds light on the optimal timing of coronary angiography in NSTEMI patients

In patients resuscitated after cardiac arrest who do not show evidence of the type of heart attack known as ST-segment elevation myocardial infarction (STEMI), receiving immediate coronary angiography did not improve survival at 90 days compared to waiting a few days before undergoing the procedure, based on findings presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Less invasive valve replacement can be safe and effective alternative for healthier patients

A new study by a team of cardiologists at Beth Israel Deaconess Medical Center led by senior and corresponding author Jeffrey Popma, MD, suggests that a minimally invasive procedure currently reserved for patients too frail to undergo surgery may in fact be a safe and effective alternative for healthier patients.

19 Mar 2019

Two-drug combinations containing calcium channel blocker significantly lowers BP

In the largest randomized controlled trial of treatment for high blood pressure ever conducted in sub-Saharan Africa, two frontline two-drug combinations that included the long-acting calcium channel blocker, amlodipine, were able to drive down blood pressure levels more than a third two-drug combination that did not include amlodipine, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

19 Mar 2019

One-off surgery could offer hope to patients with high blood pressure

A one-off operation that targets the nerves connected to the kidney has been found to maintain reduced blood pressure in hypertension patients for at least six months, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research.

18 Mar 2019

Preventative cardioverter defibrillator implantation is of little benefit to kidney dialysis patients

Placing an implantable cardioverter defibrillator in kidney dialysis patients as a preventative measure is of little benefit.

18 Mar 2019

Study highlights the need for psychiatric care to be integrated into cancer treatment

Patients with prostate, bladder or kidney cancers are at greater risk of dying if they have had psychiatric care prior to the cancer treatment. In addition, patients with these cancers show greater suicide risk than the general population, even once the data is corrected for previous psychiatric care.

18 Mar 2019

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

A new trial comparing self-expanding transcatheter aortic valve replacement (TAVR) to standard open-heart surgery for valve replacement—this time in patients with severe aortic stenosis who are considered low surgical risk—found no difference in the combined rate of disabling stroke or death from any cause at two years.

18 Mar 2019

Sweat shows promise for noninvasive health monitoring

Making a revolutionary biosensor takes blood, sweat and tears. And saliva, naturally.

15 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

New clinical development user's guide for kidney safety biomarkers

The Critical Path Institute's (C-Path) Predictive Safety Testing Consortium (PSTC) today announced availability of the User's Guide: Kidney Safety Composite Measure Biomarker for Use in Clinical Development.

15 Mar 2019

Cell therapy may be alternative strategy for treatment of chronic kidney disease

Wake Forest Institute for Regenerative Medicine scientists are working on a promising approach for treatment of chronic kidney disease - regeneration of damaged tissues using therapeutic cells.

15 Mar 2019

Long-awaited structure offers new insights into rejection of transplanted organs

Rejection of any kind is always hard to deal with, but when one's body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.

15 Mar 2019

Antiviral treatment improves survival for kidney transplant recipients infected with HBV or HCV

Prior to the development of antiviral therapy, kidney transplant recipients infected with either hepatitis B or hepatitis C experienced poor outcomes.

15 Mar 2019

Exosomes are key to SOS signal that the heart muscle sends out after heart attack, study reveals

Human cells shed exosomes. These tiny extracellular, membrane-bound vesicles can carry cargo for cell-to-cell communication, ferrying diverse loads of proteins, lipids or nucleic acids.

14 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

Study provides new understanding about blood pressure control in older adults

Until recently, physicians had generally assumed that older adults benefit from keeping their blood pressure below 140/90 mmHg. However, researchers from Charité - Universitätsmedizin Berlin have now found that this assumption does not apply to all patients with high blood pressure.

12 Mar 2019

Managing nontraditional risk factors to improve outcomes after cancer surgery

In a study of 142 patients preparing for cancer surgery, Johns Hopkins Medicine researchers say they have evidence that psychological or social risk factors such as depression, limited resilience and lack of emergency resources along with standard medical risk factors such as high blood pressure or diabetes are linked with higher risks of surgical complications.

12 Mar 2019

Computational model of the human kidney could provide safer tests for new drugs

A University of Waterloo researcher has spearheaded the development of the first computational model of the human kidney.

12 Mar 2019

$2.7 million grant supports UIC researchers to study role of arsenic in development of diabetes

A five-year, $2.7 million grant from the National Institute of Environmental Health Sciences will help researchers at the University of Illinois at Chicago answer basic questions about the role of arsenic in the development of diabetes and examine the mechanisms by which selenoproteins – found in the human body in 25 different forms – counter the effects of arsenic.

11 Mar 2019

Tiny implantable 'tea bag' senses glucose levels and automatically releases insulin

Children with Type 1 diabetes have only one option to control their blood sugar: insulin treatment. Ravaged by an autoimmune disease that attacks their own pancreas and islets -- microscopic clusters of cells that sense blood sugar and produce insulin -- patients are forced to rely on insulin from an external source.

11 Mar 2019

Nephrology News and Research

Further Reading

Study sheds light on the optimal timing of coronary angiography in NSTEMI patients

Less invasive valve replacement can be safe and effective alternative for healthier patients

Two-drug combinations containing calcium channel blocker significantly lowers BP

One-off surgery could offer hope to patients with high blood pressure

Preventative cardioverter defibrillator implantation is of little benefit to kidney dialysis patients

Study highlights the need for psychiatric care to be integrated into cancer treatment

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

Sweat shows promise for noninvasive health monitoring

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

New clinical development user's guide for kidney safety biomarkers

Cell therapy may be alternative strategy for treatment of chronic kidney disease

Long-awaited structure offers new insights into rejection of transplanted organs

Antiviral treatment improves survival for kidney transplant recipients infected with HBV or HCV

Exosomes are key to SOS signal that the heart muscle sends out after heart attack, study reveals

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Study provides new understanding about blood pressure control in older adults

Managing nontraditional risk factors to improve outcomes after cancer surgery

Computational model of the human kidney could provide safer tests for new drugs

$2.7 million grant supports UIC researchers to study role of arsenic in development of diabetes

Tiny implantable 'tea bag' senses glucose levels and automatically releases insulin

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