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Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses - the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

Study uncovers genetic clues to the cause of restless leg syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

5 Jun 2024

Insomnia linked to higher ovarian cancer risk and mortality in new genetic study

Researchers found a significant genetic link between insomnia and increased risk and mortality in epithelial ovarian cancer (EOC).

4 Jun 2024

Study reveals new insight into how human telomeres function at the molecular level

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

4 Jun 2024

GSA-MiXeR: A powerful tool to improve our understanding of heritable traits and diseases

Researchers from the University of Oslo have developed an innovative tool that promises to improve our understanding of heritable human traits and diseases.

4 Jun 2024

New computational method developed for linking DNA marks to gene activity

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

N95 respirators potential standard of care in nursing homes and healthcare settings during respiratory viral infections

Researchers examined the efficiency of surgical masks, fabric masks, N95 respirators, and KN95 respirators in lowering the SARS-CoV-2 viral loads in the exhaled breath aerosol samples of COVID-19 patients.

4 Jun 2024

Sphere Fluidics launches Cyto-CellectPLUS to accelerate cell line development workflows

Next-generation assay provides a rapid and cost-effective solution to quantify IgG production in single cells.

From Fluidic Sciences and Sphere Bio 4 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

Embryo selection based on polygenic risk scores can be unreliable and unethical

Polygenic risk scores (PRSs) are estimates of an individual's susceptibility to a specific complex trait obtained by aggregating the effects of dozens, thousands, and potentially millions of genetic variants associated with that specific trait into a single figure.

31 May 2024

Precision medicine doubles progression-free survival in young cancer patients

Cancer is the leading cause of disease-related death in children in most developed countries, and at least a quarter of these patients are diagnosed with aggressive high-risk or relapsed cancers, with an expected five-year survival rate of less than 30%.

31 May 2024

Integrating PGx testing for personalized prostate cancer treatment

Prostate cancer (PC) is a significant health concern, being the second leading cause of death among American men.

31 May 2024

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer.

31 May 2024

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide.

31 May 2024

TMPRSS2 protein facilitates SARS-CoV-2 entry via unexpected pathway

How exactly do Sars-Cov-2 particles enter host cells? An international team led by Dr Richard Brown from Dr Daniel Todt's Computational Virology group at the Department of Molecular and Medical Virology at Ruhr University Bochum, Germany, together with researchers from the Paul-Ehrlich-Institut, investigated this question.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Both too much and too little of a protein can lead to severe intellectual deficiencies

New research from the University of Lausanne reveals that both the excess and the deficiency of a single protein can lead to severe intellectual deficiencies.

30 May 2024

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

A team of researchers from the Institute of Oncology of the University of Oviedo (IUOPA), the Josep Carreras leukemia Research Institute, the University of Barcelona and the Centre for Biomedical Research in Cancer Network (CIBERONC) have demonstrated that some childhood leukemia originate during embryonic development, although they do not manifest after a few months after birth.

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Genome News and Research

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Study uncovers genetic clues to the cause of restless leg syndrome

Insomnia linked to higher ovarian cancer risk and mortality in new genetic study

Study reveals new insight into how human telomeres function at the molecular level

GSA-MiXeR: A powerful tool to improve our understanding of heritable traits and diseases

New computational method developed for linking DNA marks to gene activity

N95 respirators potential standard of care in nursing homes and healthcare settings during respiratory viral infections

Sphere Fluidics launches Cyto-CellectPLUS to accelerate cell line development workflows

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Embryo selection based on polygenic risk scores can be unreliable and unethical

Precision medicine doubles progression-free survival in young cancer patients

Integrating PGx testing for personalized prostate cancer treatment

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

TMPRSS2 protein facilitates SARS-CoV-2 entry via unexpected pathway

Researchers uncover two classes of genetic causes for pediatric chordoma

Both too much and too little of a protein can lead to severe intellectual deficiencies

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

hnRNPM's protective role in protein synthesis precision uncovered

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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