Anal Cancer News and Research

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Anal cancer is a type of cancer which arises from the anus, the distal orifice of the gastrointestinal tract. It is a distinct entity from the more common colorectal cancer.

Never married adults face higher risk of developing cancer

Adults who have never been married face a significantly higher risk of developing cancer than those who have been married, according to a large U.S. study of more than 4 million cases.

8 Apr 2026

HPV vaccination reduces risk of vulvar and vaginal lesions

Girls who are vaccinated against HPV are not only well protected against cervical cancer; they are also less likely to develop severe precancerous lesions of the vulva and vagina, particularly if they were vaccinated before the age of 17.

18 Dec 2025

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI) - designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center of the National Institutes of Health, announced findings from two HPV-related studies that highlight the potential of novel T cell therapies to achieve long-lasting remission and complete tumor regression in patients with advanced epithelial cancers.

10 Nov 2025

Anal cancer rates increasing among older white and Hispanic women in the U.S.

Anal cancer has been steadily increasing in the United States, with the biggest jumps among older women, especially white and Hispanic women - a shift that challenges assumptions about high-risk groups and who should be screened, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

Five major advances in anal and rectal cancer treatment with radiotherapy: A new era of organ-preserving options

Rectal cancer is a type of bowel cancer that develops in the last several centimeters of the large intestine, just before the anus.

2 May 2025

Gaps in HPV cancer screening and prevention identified for people living with HIV

A new study published in The Lancet HIV reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities.

12 Mar 2025

New ASTRO guideline offers radiation therapy recommendations for anal cancer

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance on the use of radiation therapy to treat adult patients with primary squamous cell carcinoma (SCC) of the anal canal and anal margin.

27 Feb 2025

New immunotherapy shows long-term benefits in preventing squamous cell carcinoma

A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.

2 Jan 2025

Long radiotherapy course shows better organ preservation in rectal cancer

The COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a better treatment for avoiding surgery, preserving the rectum and anus, and preventing regrowth of the primary tumor than a short course of radiotherapy for patients with rectal cancer – a type of bowel cancer.

11 Sep 2024

Study shows growing cancer burden in younger generations

A new large study led by researchers at the American Cancer Society (ACS) suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers.

1 Aug 2024

New national guidelines for anal cancer prevention in HIV patients based on UCSF research

New recommendations for screening and treatment are based on the results of a major national study led at UCSF.

19 Jul 2024

Hispanic and Latino men in sexual minority groups may lack awareness about HPV-related cancers

A study found multiple gaps in awareness and knowledge about the connection between the human papillomavirus (HPV) and several types of cancer among Hispanic and Latino men who identified as sexual minorities, according to results presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

Study examines the link between oropharyngeal cancer and high-risk sexual behavior

The development of head and neck cancer is increasingly linked to HPV infection, which is a sexually transmitted disease.

14 Jul 2023

Study aims to optimize radiotherapy treatment for patients with anal cancer

Reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects, recent clinical trial results have shown.

15 May 2023

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Institute of Human Virology researchers at the University of Maryland School of Medicine (UMSOM) have received two five-year awards from the National Institutes of Health's National Cancer Institute (NCI) for a total of $7.5 million.

31 Oct 2022

Rutgers study uncovers predictors of anal high-risk HPV infection

Previous sexually transmitted infections and more sexual partners predict new human papillomavirus (HPV) infections in men who have sex with men, other cisgender sexual minority men and transgender women, according to a Rutgers study.

7 Sep 2022

Treatment of precancerous anal growths in HIV patients decreases the progression to anal cancer

A team of researchers, including LSU Health New Orleans Infectious Diseases and Microbiology professor Michael Hagensee, MD, PhD, has shown for the first time that treating precancerous anal growths called high-grade squamous intraepithelial lesions (HSILs) in persons living with HIV significantly decreased the progression to anal cancer.

15 Jul 2022

Anal Cancer News and Research

Further Reading

Never married adults face higher risk of developing cancer

HPV vaccination reduces risk of vulvar and vaginal lesions

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Anal cancer rates increasing among older white and Hispanic women in the U.S.

Five major advances in anal and rectal cancer treatment with radiotherapy: A new era of organ-preserving options

Gaps in HPV cancer screening and prevention identified for people living with HIV

New ASTRO guideline offers radiation therapy recommendations for anal cancer

New immunotherapy shows long-term benefits in preventing squamous cell carcinoma

Long radiotherapy course shows better organ preservation in rectal cancer

Study shows growing cancer burden in younger generations

New national guidelines for anal cancer prevention in HIV patients based on UCSF research

Hispanic and Latino men in sexual minority groups may lack awareness about HPV-related cancers

Study examines the link between oropharyngeal cancer and high-risk sexual behavior

Study aims to optimize radiotherapy treatment for patients with anal cancer

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Rutgers study uncovers predictors of anal high-risk HPV infection

Treatment of precancerous anal growths in HIV patients decreases the progression to anal cancer

Nomogram helps predict anal cancer risk in HIV patients

Treating anal precancerous growths reduces risk of anal cancer by more than half in HIV patients

Study finds high rates of cancer among men living with HIV

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