Artificial Sweeteners News and Research

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Artificial sweetener xylitol associated with higher risk of adverse cardiovascular events

A study to be presented at ESC Congress 2026 will show that high blood levels of the artificial sweetener, xylitol, were associated with increased risk of major adverse cardiovascular events.

26 Aug 2026

What 720,000 adults reveal about artificial sweeteners and diabetes risk

A meta-analysis of six prospective cohort studies involving 721,003 adults found that higher artificial sweetener intake was associated with a 31% greater risk of developing type 2 diabetes. The evidence was rated low certainty because of substantial heterogeneity, observational study designs, and potential residual confounding, meaning the findings do not establish causation.

16 Aug 2026

Evidence shows artificial sweeteners cannot be judged as a single group

This narrative review found that non-nutritive artificial sweeteners have compound-specific and context-dependent associations with gut microbiota, metabolism, and health-related outcomes. Evidence does not support treating all sweeteners as uniformly harmful or safe, with human findings often limited or inconsistent.

23 Jul 2026

Maternal diets high in UPFs may influence children’s health years later

A narrative review of 84 publications links higher ultra-processed food intake during pregnancy and early childhood with poorer diet quality, maternal complications, childhood obesity, and potential immune, metabolic, and neurodevelopmental effects. The authors identify possible microbiome and biopsychosocial pathways but emphasize that the predominantly observational evidence cannot establish causality.

17 Jul 2026

Study finds some sweeteners can slow the growth of gut bacteria

Cambridge researchers have shown how commonly-used sweeteners slow the growth of certain gut bacteria.

16 Jul 2026

Heavily processed foods may raise heart disease risk beyond poor nutrition alone

A 2026 review in Cardiology in Review reports that higher intake of ultra-processed foods is consistently associated with greater risks of cardiovascular disease, stroke, and cardiovascular mortality across cohort studies and meta-analyses. The paper also highlights plausible mechanisms involving gut dysbiosis, oxidative stress, and NF-κB-driven inflammation, with additives such as emulsifiers, preservatives, dyes, and sweeteners discussed as potential contributors.

26 Mar 2026

Do artificial sweeteners increase appetite or food intake?

The study evaluates artificial sweeteners' role in appetite regulation, showing no significant effects on hunger or energy intake during weight management.

20 Mar 2026

Brain reward responses shift based on expectations about sweeteners

Elena Mainetto, from Radboud University, Margaret Westwater, from the University of Oxford, and colleagues at the University of Cambridge explored whether they could change how much people enjoy beverages containing sugar or artificial sweeteners by manipulating previous expectations about the drinks.

2 Mar 2026

Long-term cola intake weakens immune cell counts in controlled rat study

Replacing drinking water entirely with sugar-sweetened or sugar-free cola for eight weeks altered gut microbiota composition and immune-related indices in rats, despite no changes in body weight or blood glucose. Both beverages were associated with leukocyte reductions and organ-related biochemical shifts, with sugar-sweetened cola more strongly linked to renal markers and diet cola to elevated liver enzymes.

25 Feb 2026

High intake of ultraprocessed foods increases risk of both all-cause and cancer-specific death

Cancer survivors who consumed higher amounts of ultraprocessed foods as part of their diet had a significantly increased risk of both all-cause and cancer-specific death.

4 Feb 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025

Understanding tea's health benefits and risks

The review confirms that tea, particularly green tea, plays a crucial role in preventing cardiovascular diseases (CVDs), obesity, diabetes, and certain types of cancer.

1 Dec 2025

Experts call for bold policies to curb the health harms of ultra-processed foods

The increase of UPFs in diets worldwide presents an urgent challenge to health that demands coordinated policies and advocacy action to address, says a new three paper Series authored by 43 global experts and published in The Lancet. The Series exposes the tactics UPF companies use to drive consumption and prevent effective policy.

18 Nov 2025

How branding and peer pressure keep kids hooked on energy drinks

Children and adolescents in North East England still find energy drinks easy to access despite a voluntary UK ban, drawn by taste, price, and powerful marketing. Hydration drinks like PRIME are viewed as “healthier,” even though young consumers often misunderstand their ingredients and health impacts.

28 Oct 2025

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

This review examines how Western dietary patterns, high in ultra-processed foods, salt, and unhealthy fats, disrupt gut microbiota, impair immune regulation, and contribute to the global rise of inflammatory bowel disease (IBD). It highlights systems biology and nutritional epidemiology as essential tools to develop personalised dietary strategies and shift IBD care from treatment to prevention.

12 Oct 2025

New study suggests a connection between soft drinks and depression via the microbiome

A new study involving the German Center for Diabetes Research (DZD) provides strong evidence that sugary drinks affect not only metabolic but also mental health – especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.

25 Sep 2025