Bioluminescence News and Research

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MIT engineers use artificial intelligence to create heat-resistant RNA vaccines

MIT engineers have found a way to stabilize the lipid nanoparticles used to deliver RNA vaccines, which could allow the vaccines to be more widely distributed.

28 Sep 2026

Gene editing fails to protect beta-cell transplants from rejection

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

19 Aug 2026

The growing role of NIR-II imaging in preclinical research

NIR-II imaging has many advantages for preclinincal research as it supports deeper visualization with lower scattering and autofluorescence.

From Scintica Instrumentation Inc. 29 May 2026

Bioluminescent fungi reveal pathways for advanced biotechnology and medical applications

Like fireflies and many deep-sea creatures, certain fungi can naturally emit light through bioluminescence pathways in which specialized enzymes convert chemical energy into visible light.

21 May 2026

Copper-based nanoplatform shows promise against metastatic tumor growth

What happens if cancer cells lose both their mitochondrial energy supply and their glycolytic backup system? This question is central to a new study published in Research by researchers from Northwestern Polytechnical University and collaborating institutions.

10 May 2026

Five-target drug beats GLP-1/GIP therapy in obese diabetic mice

A Nature study reports a single-molecule GLP-1–GIP–lanifibranor quintuple agonist that targets incretin receptor-expressing cells while activating PPARα/γ/δ pathways. In obese and insulin-resistant mice, the compound reduced body weight, food intake, and hyperglycaemia more effectively than semaglutide or GLP-1R–GIPR co-agonism, while remaining a preclinical finding.

30 Apr 2026

Promega unveils cellular target engagement technology aimed at expanding the druggable proteome at SLAS 2026

Promega Corporation is launching a new live-cell target engagement platform that could close a long-standing gap between biochemical and cellular assays for understudied or difficult-to-interrogate proteins.

From Promega Corporation 27 Feb 2026

Bioluminescent tool illuminates single-cell activity in living brains

A decade ago, a group of scientists had the literally brilliant idea to use bioluminescent light to visualize brain activity.

12 Dec 2025

Ingestible capsule developed for the diagnosis of acute mesenteric ischemia

Researchers led by investigators at Mass General Brigham and Massachusetts Institute of Technology have validated an ingestible capsule in preclinical models for the diagnosis of acute mesenteric ischemia, a condition caused by blocked or reduced blood flow to the intestines.

22 Oct 2025

LUCAS technology revolutionizes rapid viral diagnostics

Mass General Brigham researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing complex biological samples.

30 May 2025

New method enables simultaneous multi-color imaging with bioluminescent proteins

Imaging live cells with fluorescent proteins has long been a crucial technique for understanding cellular behavior. While bioluminescent proteins offer several advantages over fluorescent proteins, the limited availability of color variants has made it difficult to observe multiple targets simultaneously.

23 Jan 2025

Brain tumors exploit body's daily rhythms to fuel growth

Scientists explore how daily glucocorticoid signaling influences glioblastoma growth and synchronizes its circadian rhythms with the host.

18 Dec 2024

Targeted gene therapy shuts down cancer cells' energy centers

Researchers are shining a light on cancer cells' energy centers – literally – to damage these power sources and trigger widespread cancer cell death.

14 Dec 2024

New method harnesses light to activate neurons in the brain

University of Rochester researchers have demonstrated a noninvasive method using BL-OG, or bioluminescent optogenetics, that harnesses light to activate neurons in the brain.

3 Oct 2024

Barcoding technology reveals secrets of cancer metastasis

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death.

26 Sep 2024

New CRISPR model offers deeper insight into prostate cancer metastasis

A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given Weill Cornell Medicine researchers and their colleagues a deeper insight into how prostate cancer spreads or metastasizes.

23 Sep 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

Innovative 3D-printed implants and bioluminescent tools transform sensory process studies

A sensory process such as pain is no ordinary phenomenon - it's a symphony of neural and vascular interactions orchestrated by the brain and spinal cord.

21 May 2024