Blastocyst News and Research

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Blocking xenophagocytosis improves donor cell survival and interspecies organ generation

Xenophagocytosis is a natural immune process that limits interspecies organ generation by eliminating living donor cells, report researchers at Institute of Science Tokyo, Japan.

31 Jul 2026

Modern IVF treatment boosts live births while lowering twin pregnancies

Modern IVF treatment can now achieve substantially higher success rates than historical approaches while dramatically reducing twin and triplet pregnancies, according to new research presented today at the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE).

7 Jul 2026

Uterine aging may reduce donor egg pregnancy success after 49

A major new study suggests that age-related changes in the uterus may contribute to poorer pregnancy outcomes, with women aged 49 and over experiencing lower live birth rates and higher miscarriage risk despite donor-oocyte treatment.

5 Jul 2026

Interspecies blastocyst complementation generates generates rat-derived kidneys in mice

Kidney transplantation remains the most effective treatment for end-stage kidney disease, yet a severe shortage of donor organs continues to limit access for millions of patients worldwide.

11 Jun 2026

Optically invisible culture dishes improve embryo imaging in IVF

Selecting the healthiest embryo is one of the most important steps in in‑vitro fertilization (IVF), yet it remains one of the most uncertain.

4 Feb 2026

IVF study finds shorter insemination protects embryo availability without harming success

Short-term sperm–oocyte co-incubation during IVF cycles with only one or two retrieved oocytes produced cumulative live birth rates comparable to conventional overnight insemination. It also improved fertilisation metrics and reduced cancellation or no-embryo cycles, suggesting practical laboratory advantages without improving overall live birth probability.

4 Feb 2026

Maternal age drives embryo arrest independently of chromosomal errors

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled "Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos."

20 Nov 2025

Study: Common test to assess viability of IVF embryos may be flawed

A test deployed in many fertility clinics to assess the viability of embryos for use in IVF is likely to overestimate the number of embryos with abnormalities, suggests a study published today.

23 Oct 2025

Researchers achieve proof of concept for generating eggs from somatic cells

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos.

17 Oct 2025

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Researchers found that THC, the psychoactive compound in cannabis, alters oocyte gene expression, spindle formation, and chromosome segregation, lowering embryo euploidy rates in IVF. This provides direct human evidence linking cannabis exposure to impaired female fertility outcomes.

10 Sep 2025

FEMI helps predict IVF outcomes with greater accuracy

FEMI, an AI model for IVF, uses 18 million images to improve embryo assessment, offering a non-invasive, cost-effective solution for better success rates.

15 Jul 2025

Male age over 45 linked to higher miscarriage risk in IVF with donor eggs

A new international study presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) reveals that IVF cycles involving male partners over the age of 45 carry significantly increased miscarriage risks and lower live birth rates – even when young donor eggs are used.

30 Jun 2025

Blood cell-free RNA signatures can predict preterm birth months in advance

Children born before 37 weeks of gestation have a considerably increased risk of dying before they reach the age of five.

25 May 2025

Smaller hatching embryos more likely to be genetically healthy

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 5, 2025, titled "Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?"

9 Apr 2025

Molecular pathways in human cells reveal potential for developmental pause

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother.

26 Sep 2024

PRP intraovarian injection improves the number and quality of blastocysts in mouse models

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 13, 2024, entitled, "Intraovarian PRP injection improves oocyte quality and early embryo development in mouse models of chemotherapy-induced diminished ovarian reserve."

24 Sep 2024

IVF transfer day does not impact overall success rates, study reveals

In IVF treatment, embryos are traditionally transferred in the uterus three days after fertilization. Due to improvements in laboratory techniques, this is now also possible after five days.

17 Sep 2024

Revolutionary 3D imaging model enhances IVF blastocyst selection

Innovative research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, has introduced a novel 3D imaging model designed to identify features of blastocysts – the early stage of development for an implanted embryo – associated with successful pregnancies.

8 Jul 2024

Primitive endoderm in early embryos may be key to creating new effective fertility treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

24 Jun 2024