CXCL10 News and Research

RSS

Scientists map protective cell networks hiding dormant breast tumor cells

Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumors and identified distinct neighborhoods of proliferating and dormant cells.

31 Jul 2026

Breakthrough enables continuous laboratory growth of human norovirus

Researchers at Baylor College of Medicine report in Science Advances a breakthrough in human norovirus (HuNoV) research.

4 Feb 2026

Remodeling the tumor microenvironment to unlock CAR-T cell potential

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor microenvironment (TME).

22 Dec 2025

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents - and they've shown a possible route to reducing its likelihood.

10 Dec 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

Goat milk boosts muscle health better than cow’s milk in animal study

Dairy products, especially low-fat and fortified goat milk, significantly improved muscle mass, reduced inflammation, and positively modulated gut microbiota in a mouse model of sarcopenia. These findings suggest tailored dairy interventions could help delay age-related muscle loss.

21 Jul 2025

Simpler virus testing approach could reduce unnecessary PCR tests in high-risk settings

The COVID-19 pandemic yielded important advances in testing for respiratory viruses, but it also exposed important unmet needs in screening to prevent the spread of infections in high-risk settings.

24 Jun 2025

Inflammation and immune dysregulation drive breast cancer in aging women

Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to the role of pro-inflammatory cytokines and CXC chemokines in tumor development and immune system modulation.

20 Jun 2025

How your skin’s microbes shape immunity, inflammation, and chronic skin disease

Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your lifespan. This review explains how disruptions in this microbiome-immune dialogue can lead to eczema, psoriasis, or acne.

2 Apr 2025

MEMPHIS system sheds light on vaccine response differences across ages

mRNA vaccines saved lives during the COVID-19 pandemic, but older people had less of an immune response to the vaccines than did younger adults. Why? Boston Children's researchers, led by Byron Brook, PhD, and Ofer Levy, MD, PhD, have found some answers, while providing proof-of-concept of a new system that can model vaccine responses in a dish.

15 Nov 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

A faster, cheaper method to detect immune autoantibodies in whole blood

Researchers developed a quick and affordable whole-blood assay to detect autoantibodies against type I IFNs, enabling rapid diagnostics for immune disorders. This new method has potential clinical impact by addressing key limitations of current tests.

25 Sep 2024

Frequent infections and pathobionts boost children's nasal immunity, study reveals

Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.

2 Jul 2024

New biomarker predicts immunotherapy response in gastrointestinal cancers

Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) therapy remains low.

30 Apr 2024

Study reveals inflammation's role in long COVID's lingering effects

Large-scale study found that long COVID patients exhibit sustained inflammation and specific immune responses associated with varying symptoms, highlighting the importance of personalized treatment approaches.

9 Apr 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans.

4 Dec 2023

Herring roe oil's potential in psoriasis treatment

Researchers investigated the use of herring row oil to treat psoriasis, a non-communicable skin disease.

12 Sep 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

Intranasal inoculation study sheds light on nasal and systemic immune responses to SARS-CoV-2

Study reveals the events accompanying the COVID-19 infection cascade in the nasal mucosa and free circulation

1 Aug 2023