Cold Sores News and Research

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Scientists identify ANKIB1 as key regulator of innate immune signaling

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.

6 Mar 2026

Scientists capture real-time action of antiviral drugs on herpes

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

30 Dec 2025

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 Oct 2025

Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research on July 25.

17 Oct 2025

FDA shares safety guidance for people considering microneedling

Being pricked by tiny needles may sound like a strange way to make your skin look better, but that's the concept behind a skin care technique called microneedling.

16 Oct 2025

Discovery reveals hidden differences in herpes virus cultures

Matthew Taylor likened his recently published work alongside doctoral student Gary Dunn to kicking over a rock. Once the discovery was made, it was time to see what lay beneath.

3 Oct 2025

Antiviral treatment shows no benefit for early Alzheimer’s patients

The idea that herpes infections trigger or contribute to Alzheimer's disease has been gaining favor among some scientists, raising hope that herpes treatments could slow progression of Alzheimer's symptoms among patients.

30 Jul 2025

Genetically modified herpes virus shows promise against advanced melanoma

The herpes simplex virus type 1 (HSV-1), which affects almost two-thirds of the world's population and is generally associated with oral herpes, may cause painful cold sores or fever blisters around the mouth.

9 Jul 2025

Herpes virus reshapes the human genome's architecture to aid its replication

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves.

19 Jun 2025

New target identified for preventing cold sores and genital herpes

Scientists have a new target to prevent cold sores after University of Virginia School of Medicine researchers discovered an unexpected way the herpes virus re-activates in the body.

28 Feb 2025

Study shows how herpes viruses contribute to Alzheimer's disease in aging brains

Researchers from Cleveland Clinic's Genome Center outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains.

24 Feb 2025

Herpes infections affect 846 million people worldwide

Around 846 million people aged between 15 and 49 are living with genital herpes infections – more than 1 in 5 of this age-group globally – according to new estimates released today.

11 Dec 2024

Unraveling the mystery of viral evolution

All organisms - from fungi to mammals - have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with the ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

Comprehensive review highlights Aloe vera's versatile biological activities and its potential applications in medicine and cosmetics while addressing its safety concerns.

11 Jul 2024

First global estimates of economic costs of genital herpes infections

Genital herpes infections and their related complications lead to billions of dollars in health care expenditures and productivity losses globally, according to the first ever global estimates of the economic costs of these conditions.

1 Jul 2024

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

Researchers examined the effect of Bacillus Calmette-Guérin (BCG) vaccination on attenuating herpes labialis (cold sore) recurrences.

14 Sep 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

Viral shedding rate declines rapidly during the first year among people with HSV-1 genital infections

People with a genital infection of the herpes simplex virus type 1 (HSV-1), which usually causes cold sores, frequently shed the virus in the first months after infection, raising the risk that they might spread the virus to sexual partners during this time.

24 Oct 2022

Dentists need to be aware of and alert to oral monkeypox symptomology, warn experts

Monkeypox is an increasing worldwide problem recently declared a public health emergency in the United States. Among classical symptoms that include fever, muscle aches, lymph node swelling and rash are oral lesions present in up to 70% of cases.

22 Aug 2022