Glycemia News and Research

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Glycemia or glycæmia is the concentration of glucose in the blood. It is usually expressed in milligrams per deciliter (mg/dl) in the US and other countries. It may also be expressed in millimol per decilitre (mmol/dl) especially in Europe. Both of these are SI units.

Consuming fat before carbohydrates reduces post-meal blood glucose

In treating diabetes, post-meal elevation of glucose levels is an important therapeutic target. Existing clinical studies indicate that eating vegetables, protein, or fat before carbohydrates can moderate a post-meal rise in blood glucose, pointing to the potential of meal-sequencing as a simple and sustainable dietary strategy.

8 Oct 2026

Same foods, different timing, very different glucose patterns

In a randomized crossover study of 22 healthy, normal-weight Chinese men, consuming canola oil alone or with spinach before a high-glycemic mashed-potato meal produced flatter post-meal glucose and insulin responses than spinach alone or no preload. The effects were associated with increased GLP-1 signaling and slower gastric emptying, with the findings indicating that the unsaturated oil was the primary driver of the metabolic response.

3 Sep 2026

A four-week spice experiment challenges expectations about post-meal benefits

Culinary doses of herbs and spices did not significantly alter postprandial endothelial function, glycemia, or lipemia after four weeks of corresponding spice-containing diets in adults at cardiometabolic risk. The findings suggest that acute spice-related effects may be less apparent with longer-term exposure, although the study may have been underpowered to detect modest benefits.

17 Aug 2026

The best meal timing for blood sugar may be earlier dinners

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9 Jun 2026

Five-target drug beats GLP-1/GIP therapy in obese diabetic mice

A Nature study reports a single-molecule GLP-1–GIP–lanifibranor quintuple agonist that targets incretin receptor-expressing cells while activating PPARα/γ/δ pathways. In obese and insulin-resistant mice, the compound reduced body weight, food intake, and hyperglycaemia more effectively than semaglutide or GLP-1R–GIPR co-agonism, while remaining a preclinical finding.

30 Apr 2026

Parents’ intake of sugar substitutes may influence offspring gut biology, study finds

A mouse study in Frontiers in Nutrition found that parental sucralose and stevia intake altered gut microbiota, short-chain fatty acids, and gene expression across generations, with sucralose showing the stronger and more persistent effects. The changes were transmitted to offspring not directly exposed to the sweeteners, although several effects were attenuated by the F2 generation.

13 Apr 2026

Firmer potatoes lower post-meal blood sugar spikes

Minimally cooked potatoes may reduce blood sugar spikes, but benefits are short-lived and specific to certain populations, as shown in recent research.

23 Mar 2026

Researchers show red blood cells drive better glucose tolerance at high altitude

Chronic hypoxia improves glucose tolerance in mice through insulin-independent mechanisms, with red blood cells acting as a major systemic glucose sink. Increased erythrocyte production and altered glycolytic flux help reduce circulating glucose while supporting oxygen delivery to tissues.

22 Feb 2026

Magnesium lower fasting blood sugar in older adults

Magnesium boosts fasting glucose control in older adults with deficiency, but preventing diabetes progression may need more than just mineral correction.

13 Feb 2026

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.

14 Dec 2025

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025

Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

Are mushrooms more than a low-calorie food? New analysis explains their hidden advantages

Whole mushroom consumption shows consistent benefits for cardiometabolic health, lowering triglycerides in self-chosen diets and improving fasting glucose in a single healthy dietary pattern trial. Early evidence also suggests increases in salivary IgA and possible blood pressure improvements, with no adverse biomarker effects reported.

16 Nov 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

Physical activity linked to higher overnight glucose in pregnancy hyperglycemia

Research shows that more daytime movement in pregnant women with hyperglycemia can raise nighttime blood sugar, highlighting the need for further investigation.

20 Oct 2025

Diabetic teens with poor glycemic control more likely to develop neuropathy in adulthood

Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes, research co-led by University of Michigan suggests.

9 Oct 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

How raspberry leaf tea reduces insulin surges from table sugar

Trial shows that raspberry leaf tea blunts sucrose-induced glucose and insulin surges, offering a natural strategy for moderating blood sugar without the side effects of pharmaceutical enzyme inhibitors.

2 Sep 2025

How dietary formaldehyde links to worsening diabetes and memory loss

A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip away at memory, but also points to dietary patterns and emerging therapies that could help reduce the risk.

20 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025