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Norrin treatment prevents vision loss in diabetic rats

Over 100 million people in the U.S. are affected by diabetic retinopathy, a complication of diabetes that affects the eyes.

30 Oct 2026

Myeloid immune cells play key roles in aortic health and disease

The aorta is often viewed primarily as the body's largest blood vessel-a durable conduit that delivers oxygen-rich blood from the heart to every organ.

30 Oct 2026

Targeted drug combination extends survival in advanced kidney cancer

Results of a phase 1/2 trial led by Roswell Park Comprehensive Cancer Center show that combining the targeted therapies bevacizumab (Avastin) and pazopanib (Votrient) significantly extends both progression-free and overall survival in patients with the most common type of kidney cancer.

28 Oct 2026

Plasma proteins offer clues to biological aging and mortality risk

A new study published in Geromedicine has identified 17 plasma proteins associated with all-cause mortality in older adults and found that several of these proteins also track with measures of biological aging across multiple organ systems.

27 Oct 2026

Smart probe makes aggressive breast cancer cells glow during surgery

Surgical removal of a tumor remains the primary defense against most solid cancers. However, for surgeons in the operating room, differentiating between the outer edges of a tumor and healthy tissue is a challenge.

26 Oct 2026

Researchers discover how faulty matrix structure leads to cell death in newly formed bone

Bone cells called osteocytes help maintain skeletal strength, but how newly formed osteocytes survive remains unclear.

26 Oct 2026

Altered fatty acid metabolism drives glioblastoma growth and treatment resistance

Glioma is the most common primary malignant brain tumor in adults, and glioblastoma (GBM), particularly IDH (Isocitrate dehydrogenase)-wildtype disease, has the poorest prognosis.

21 Oct 2026

Could a hormone from our bones reveal early signs of insulin resistance?

Research reveals a link between osteocalcin and insulin resistance in obese children, suggesting early metabolic changes before glucose tolerance impairment.

21 Oct 2026

Women with low bone density reported less pain after taking pine bark extract

A randomized clinical trial involving 67 women with osteopenia or stable osteoporosis found that three months of Pycnogenol® supplementation improved self-reported bodily pain and vitality scores compared with placebo. However, overall disease-specific quality of life did not significantly improve, and the six-month findings were insufficient to establish long-term benefits or safety.

15 Oct 2026

Heart failure alters bone marrow to promote harmful inflammation

Heart failure (HF) alters the bone marrow (BM), reducing protective cells that regulate inflammation, reports a study conducted at Science Tokyo.

15 Oct 2026

A simple handgrip test offers new clues about long COVID

Weaker handgrip strength correlates with severe long COVID symptoms, highlighting its potential as a measure for muscle dysfunction and recovery challenges.

12 Oct 2026

Polymeric nanomedicine strategies improve solid tumor immunotherapy outcomes

Solid tumors are not merely collections of malignant cells but complex ecosystems comprising tumor cells, stromal cells, and the extracellular matrix (ECM).

9 Oct 2026

Disrupted circadian rhythms may influence tumor immunity and cancer spread

Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal cancer.

8 Oct 2026

New model predicts growth hormone therapy response in children with short stature

Idiopathic short stature (ISS) describes children whose height is substantially below the expected range for their age and sex without any identifiable medical cause.

5 Oct 2026

Is a high-protein diet hard on your kidneys?

From temporary changes in kidney filtration to the competing nutritional needs of older adults and children, researchers examine when high protein intake may shift from adaptation to concern.

5 Oct 2026

Placental health in late pregnancy linked to childhood ADHD

Attention deficit/hyperactivity disorder (ADHD) in children may be associated with problems with the health of the placenta during late pregnancy, according to a new study by University of Iowa Health Care researchers.

30 Sep 2026

From espresso to filter coffee, brewing may shape what reaches your gut

A focused narrative review traces how caffeine, chlorogenic acids, and coffee fibers move through the gut and interact with microbes. The authors identify plausible links between the microbiome and liver health, but human studies have not shown that microbiome changes cause coffee’s reported metabolic benefits.

28 Sep 2026

EGFR co-targeting and nanotechnology offer new triple-negative breast cancer therapies

Triple-negative breast cancer (TNBC) remains one of the most challenging forms of breast cancer to treat because it lacks the estrogen, progesterone and HER2 receptors that enable targeted treatment in other breast cancer subtypes.

24 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

Older adults with higher polyphenol intake were less likely to have mild cognitive impairment

In a cross-sectional study of 92 older Italian memory-clinic patients, higher habitual intake of total dietary (poly)phenols and several specific subclasses was associated with a lower likelihood of mild cognitive impairment (MCI). Total (poly)phenol intake was not associated with cognitive test performance or circulating inflammatory biomarkers, and the authors cautioned that the small observational study cannot establish causality.

20 Sep 2026