Growth Factor News and Research

RSS

Semaglutide extended lifespan in older female mice, but that was not the only finding

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced calorie intake alone.

3 Sep 2026

Biodegradable 'nanobone' material helps body regrow jawbone

For children born with cleft lip and palate, repairing gaps in the jawbone often means waiting until they are 10 to 12 years old before undergoing invasive bone graft surgery.

3 Sep 2026

Researchers uncover molecular pathway driving craniosynostosis

Craniosynostosis is a congenital developmental disorder in which the skull's cranial sutures fuse prematurely.

28 Aug 2026

Fleeting interactions between membrane sugar chains control cell division

Acting as an armor, a scaffold, and a communication platform in one, our cells' plasma membrane lies at the heart of many crucial cellular processes.

27 Aug 2026

From caffeine to trigonelline, coffee has surprising links to muscle biology

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose uptake, and protein turnover. Human studies reported associations with greater muscle mass and lower frailty or functional impairment, but most evidence remains observational or preclinical and cannot establish causality.

25 Aug 2026

Blood protein biomarkers predict future disability risk in very old adults

Japan has one of the world's fastest-aging populations, but maintaining independence into very old age remains a growing public health challenge.

21 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

Cocoa looks promising for mood, but the brain benefits come with a catch

A review of clinical and preclinical studies suggests cocoa polyphenols may support mood, neuroplasticity, cerebral blood flow, and gut-brain signaling through pathways involving BDNF/CREB, inflammation, and oxidative stress.

17 Aug 2026

Sprint exercise sends a very different molecular signal through the body

Sprint-interval exercise triggers a much larger and faster shift in circulating proteins and metabolites than moderate-intensity exercise, revealing distinct patterns of predicted communication between organs. The findings suggest that exercise intensity shapes systemic molecular signaling, with skeletal muscle and adipose tissue emerging as potential source and target tissues linked to cardiometabolic health.

16 Aug 2026

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

A new research paper was published in Volume 17 of Oncotarget on August 7, 2026, titled "Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers."

10 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

Hyperfunction theory offers fresh insights into mechanisms driving human aging

A new research perspective was published in Volume 18 of Aging on July 24, 2026, titled "A brief history of the hyperfunction theory of aging and future directions."

6 Aug 2026

Stanford researcher receives NIH grant to develop molecular imaging agent for localizing lung tumors during surgery

Lung cancer remains the leading cause of cancer-related deaths, and surgery is a critical treatment option for early-stage disease.

6 Aug 2026

Korean study finds no overall childhood cancer link with maternal diabetes

Researchers followed 549,851 Korean children and found no statistically significant association between maternal diabetes and overall childhood cancer. The analysis linked maternal diabetes to an 81% higher relative risk of urinary tract cancer, but the absolute difference was only 37 additional cases per 100,000 offspring.

4 Aug 2026

Researchers suggest a potential therapeutic strategy for muscle loss associated with obesity

Obesity has been linked to skeletal muscle loss and deterioration. While M2 macrophages may play a role in regulating muscle function, the underlying mechanisms remain poorly understood.

4 Aug 2026

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

A review finds that restricting protein, particularly methionine, isoleucine, and valine, may improve metabolism and influence key aging pathways, largely in experimental models. Short human studies suggest metabolic benefits, but effects on lifespan remain unknown and restriction may harm people with unmet or increased protein needs.

3 Aug 2026

Consuming less protein could have greater health benefits and extend lifespan

Protein-fortified foods are popping up everywhere, from cereal and coffee to even protein water. But a new review covering over 350 papers on protein restriction and aging-publishing July 31 in the Cell Press journal Cell Press Blue-suggests that consuming less protein could have greater health benefits and could, in some cases, extend lifespan.

31 Jul 2026

Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancer

A combination of two immunotherapy drugs showed encouraging activity when added to standard chemotherapy given prior to surgery for patients with high-risk, early-stage HER2-negative breast cancer, according to phase 2 clinical trial results from the ongoing I-SPY2 clinical trial platform.

30 Jul 2026

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

28 Jul 2026

Novel bioinspired dressing uses body force to heal wounds

A bioinspired material, developed by scientists at Imperial College London, accelerates wound healing and the repair of human skin.

27 Jul 2026

Growth Factor News and Research

Semaglutide extended lifespan in older female mice, but that was not the only finding

Biodegradable 'nanobone' material helps body regrow jawbone

Researchers uncover molecular pathway driving craniosynostosis

Fleeting interactions between membrane sugar chains control cell division

From caffeine to trigonelline, coffee has surprising links to muscle biology

Blood protein biomarkers predict future disability risk in very old adults

Glioma microenvironment emerges as key target for future therapies

Cocoa looks promising for mood, but the brain benefits come with a catch

Sprint exercise sends a very different molecular signal through the body

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

Hyperfunction theory offers fresh insights into mechanisms driving human aging

Stanford researcher receives NIH grant to develop molecular imaging agent for localizing lung tumors during surgery

Korean study finds no overall childhood cancer link with maternal diabetes

Researchers suggest a potential therapeutic strategy for muscle loss associated with obesity

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

Consuming less protein could have greater health benefits and extend lifespan

Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancer

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Novel bioinspired dressing uses body force to heal wounds

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News