Haloperidol News and Research

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Haloperidol is a typical antipsychotic. It is in the butyrophenone class of antipsychotic medications and has pharmacological effects similar to the phenothiazines.

What medicine-exposed rats reveal about the next urban zoonotic threat

Researchers found that more than half of urban rats sampled from low-income communities in Salvador, Brazil, carried active pharmaceutical ingredients in their brain tissue. These pollutants were associated with altered zoonotic infection patterns, including lower Leptospira infection probability in rats carrying azithromycin and higher Capillaria infection probability in rats carrying citalopram.

22 May 2026

Autism risk rises with multiple medications taken during pregnancy

A study links maternal use of cholesterol-inhibiting medications during pregnancy to increased autism risk in children, urging caution in prescribing practices.

22 Apr 2026

Certain prenatal medications linked to increased risk of autism

A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in children.

20 Apr 2026

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Early diagnosis of Dementia with Lewy Bodies could be improved by cognitive profiling

Cognitive profiles for early diagnosis of Dementia with Lewy bodies (DLB) have been outlined in a new study, out today in Alzheimer's & Dementia.

10 Jan 2025

Combination treatment improves symptoms of agitated delirium in end-of-life cancer patients

Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

16 Sep 2024

Repurposing human-approved drugs for prion disease treatment

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

16 May 2024

New review explores safer treatment approaches for acute agitation in pregnant patients

A recent review article provides critical insights into the management of acute agitation in reproductive-age females and during pregnancy within the emergency departments (EDs).

7 May 2024

Risks of antipsychotic use in dementia extend beyond previous alerts, study shows

Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.

23 Apr 2024

Study shows antipsychotic drugs increase health risks in dementia patients

Study found that antipsychotic drug use in dementia patients is linked to increased risks of stroke, heart failure, and other serious conditions.

18 Apr 2024

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, compared with non-use, finds a study published by The BMJ today.

17 Apr 2024

Research identifies characteristics linked with higher risk of sudden cardiac arrest in people with type 2 diabetes

New research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has identified a range of characteristics associated with a higher risk of sudden cardiac arrest in individuals with type 2 diabetes.

4 Oct 2023

Changes in dopamine levels in the brain affect emotion-recognition

Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels of dopamine in the brain, say researchers at the University of Birmingham.

24 May 2022

Study shows massive variations in prescribing of “comfort kit” medications by hospice agencies

When a person nearing the end of their life enters hospice care, their hospice agency's doctors may prescribe a "comfort kit" of small amounts of medications that their caregivers can give them in case of urgent, distressing symptoms such as severe anxiety, agitation, delirium, nausea and more.

13 May 2022

Dopamine plays a significant role in recognizing human emotions, new study reveals

The neurotransmitter dopamine, famous for its role in reward, is also involved in recognizing emotions, according to new research published in JNeurosci.

3 May 2022

Antipsychotic drugs associated with increase in risk of breast cancer

Researchers at Washington University School of Medicine in St. Louis have found that many commonly prescribed antipsychotic medications are associated with a significant increase in risk of breast cancer.

6 Dec 2021

Scientists use anti-psychotics to treat flies displaying behavioral problems linked to schizophrenia-associated genes

Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.

20 May 2021

Mice experiencing hallucination-like events provide clues to understand psychosis

The humble lab mouse has provided invaluable clues to understanding diseases ranging from cancer to diabetes to COVID-19. But when it comes to psychiatric conditions, the lab mouse has been sidelined, its rodent mind considered too different from that of humans to provide much insight into mental illness.

1 Apr 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Transcriptomics identifies possible COVID-19 therapies

By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on bioRxiv preprint server.

26 Oct 2020