Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Scientists discover how excess dietary salt drives 'lean MASH'

Fatty liver disease is commonly associated with obesity, yet a growing number of people with normal body weight develop a severe form of the condition.

29 Sep 2026

Exercise may reshape your gut microbiome to support recovery

Research reveals how exercise alters gut microbes, influencing recovery and proposing 'intestinal rehabilitation' for those with limited exercise capacity.

29 Sep 2026

Why one gut microbe is attracting attention in heart failure research

Researchers found that chronic systolic heart failure caused by nonischemic cardiomyopathy was associated with reduced gut microbial diversity, depletion of Bifidobacterium, and lower microbial short-chain fatty acid production potential. Higher Bifidobacterium abundance and higher circulating indole-3-propionic acid levels were associated with milder disease and clinical improvement, although the findings do not establish causality.

27 Sep 2026

Study finds oral hormone replacement therapy increases venous thromboembolism risk

Current use of oral menopausal hormone therapy (commonly known as hormone replacement therapy or HRT) is associated with an increased risk of blood clots in legs / lungs regardless of dose or treatment duration, finds a large Danish study published by The BMJ today.

23 Sep 2026

New spin-out launches technology to revolutionize hormone disorder diagnosis

The University of Birmingham and Imperial College London have announced the launch of Intelligent Mass Spec Solutions Ltd (IMS Solutions), a new spin-out that is set to revolutionize diagnosis of conditions featuring disordered steroid hormone metabolism.

22 Sep 2026

Waist-to-height ratio reliably detects chronic liver disease risk in children

Metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most common chronic liver disease in children and adolescents, closely mirroring the global rise in childhood obesity.

22 Sep 2026

Garvan research reveals hidden inflammation behind high colon cancer risk

New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different.

22 Sep 2026

Siemens Healthineers and Novo join forces to advance care for people living with MASLD and MASH

Siemens Healthineers and Novo have announced a collaboration focused on advancing care for people living with metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH).

From Siemens Healthineers 22 Sep 2026

New mRNA vaccine expands flu protection options for older adults

Every fall, millions of Americans heed the call to get their annual flu shot. Getting vaccinated reduces the risk of severe illness, hospitalization, and death from influenza.

20 Sep 2026

Study identifies bile acid that helps reduce excess fat accumulation in the liver

Non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD), is a common condition that causes excess fat to build up in the liver, affecting about one-quarter of adults worldwide.

17 Sep 2026

Study defines early-onset cirrhosis caused by fatty liver disease

Researchers at University of California San Diego School of Medicine have published the first study to define early-onset cirrhosis caused by metabolic dysfunction-associated steatotic liver disease (MASLD), a condition known as fatty liver disease.

16 Sep 2026

New treatment option approved in Japan for rare genetic liver disorders

A new indication for an existing drug has been approved in Japan to treat patients with progressive familial intrahepatic cholestasis (PFIC) types 1 and 2, a group of rare genetic liver disorders.

15 Sep 2026

Childhood chemotherapy leaves lasting DNA damage in healthy cells

Chemotherapy, which saves the lives of many children with cancer, causes previously unknown DNA alterations in the liver and leaves genetic footprints in other healthy cells as well.

10 Sep 2026

Study reveals hidden DNA damage from childhood chemotherapy

The amount of DNA damage caused by certain chemotherapies used to effectively treat childhood cancer has been revealed, along with a hidden impact on the liver, paving the way for future research into new ways to mitigate these impacts.

10 Sep 2026

Symptomless liver condition linked to heart and kidney disease

A common liver condition thought to be harmless could be dramatically increasing the risk of heart disease, kidney failure and premature death, according to a new review led by University of Manchester and Northern Care Alliance NHS Foundation Trust researchers.

10 Sep 2026

New integrated framework advances precision surgery for liver cancer

Hepatocellular carcinoma is the sixth most common malignancy and the third leading cause of cancer-related death globally.

9 Sep 2026

Study finds weak evidence for post-hospital alcohol use disorder treatment

A systematic review by researchers at the University of Colorado Anschutz and Yale University found limited evidence that hospital-based interventions can help people with alcohol use disorder connect with outpatient treatment after they leave the hospital.

8 Sep 2026

Could scorpion venom inspire new treatments for liver disease?

Scorpion venom peptides show promising anti-inflammatory, antiviral, analgesic, and immunomodulatory effects, with experimental evidence suggesting that some candidates could target pathways involved in chronic liver disease and viral hepatitis. The review highlights Kv1.3-blocking peptides and antiviral compounds as potential therapeutic leads, while emphasizing that limited hepatic efficacy data, poor pharmacokinetics, immunogenicity, and manufacturing challenges must be overcome before clinical translation.

8 Sep 2026

Gut bacterial metabolite linked to inflammation in liver disease

Researchers have identified a link between specific activities in gut bacteria and the liver disease PSC.

4 Sep 2026

Dual-drug microneedle patch targets inflammation and fat browning

The worldwide obesity crisis has become a dominant public health crisis across the globe. Over 3 billion people worldwide currently suffer from obesity, and forecasts warn the number will rise above 4 billion by 2035, accounting for more than half the global population.

4 Sep 2026