Manganese News and Research

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Rice, seafood and water may help explain striking differences in metal exposure across US communities

Researchers compared urinary trace-metal profiles across 666 adults from six ethnic groups in three US cohorts, with up to 19 elements measured and paired serum measurements available for the Asian Indian MASALA cohort. Distinct metal patterns emerged across populations, with the findings suggesting that diet, drinking-water sources, regional hydrogeology, urban-rural conditions, smoking, and physiological handling may all contribute to differences in exposure profiles.

8 Sep 2026

Disrupted RNA methylation pathway accelerates Alzheimer’s and Parkinson’s risks

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Ferroptosis-based therapy shows promise for advanced prostate cancer treatment

A recent review explores the rapidly expanding field of ferroptosis-based therapy for prostate cancer, presenting ferroptosis as a promising strategy to overcome resistance in advanced and castration-resistant prostate cancer (CRPC).

6 Aug 2026

Review outlines effective approaches to reduce recurrent hepatic encephalopathy

Hepatic encephalopathy (HE) is a neurologic complication of advanced liver disease, causing impaired functioning, reduced quality of life (QOL), and increased hospitalisation and mortality.

31 Jul 2026

New microparticles improve biofilm removal from wounds and surgical instruments

Newly developed microparticles can infiltrate stubborn bacterial matrices and release tiny oxygen bubbles to clean surfaces and wounds more efficiently than hydrogen peroxide or other cleaning agents alone, researchers at the University of Illinois Urbana-Champaign report.

9 Jul 2026

Global groundwater maps reveal hidden manganese risk for 220 million people

Machine learning maps suggest that about 180 to 220 million people may rely on untreated groundwater with manganese above the WHO’s updated 80 µg/L guideline. The study places manganese exposure on a similar global scale to arsenic and fluoride, yet shows it remains far less visible in groundwater monitoring.

8 Jul 2026

Using manganese ferrite nanoparticles to better harness heat against cancer

Scientists have long known that heat can be used to help fight cancer. But heating up tumors and cancer cells is trickier than it sounds.

7 Jul 2026

Dutch study shows why plant-based eating can miss key nutrients

A Dutch dietary modeling study found that replacing major animal-based protein sources with plant-based substitutes reduced protein, EAA, vitamin, and mineral intake across age groups. Older adults, adolescents, children, and women were especially vulnerable to shortfalls, highlighting the need for planned substitutions, fortified foods, and age-specific dietary guidance.

3 Jul 2026

New discovery sheds light on how the human body controls Salmonella infections

Salmonella, an infection that causes diarrhea, fever, and abdominal pain, is the most common form of bacterial food poisoning in the U.S., sickening more than a million people each year.

26 Jun 2026

Novel metal-free prodrug suppresses cancer spread in preclinical models

A carefully designed metal-free carbon monoxide prodrug may help prevent some of the deadliest forms of cancer from spreading, according to researchers at Weill Cornell Medicine.

12 Jun 2026

Silica nanoparticles dampen early allergy signals in mouse mast cells

This in vitro study found that negatively charged SiO2 nanoparticles suppressed antigen-induced degranulation and activation-marker changes in IgE-sensitized mouse bone marrow-derived mast cells. By contrast, mTiO2 nanoparticles showed cytotoxic and pro-inflammatory effects, including enhanced DNP-induced IL-6 release, suggesting nanoparticle composition can shape early allergic immune responses.

24 May 2026

Baby teeth show when metal exposure may affect brain development

The study identifies critical windows of metal exposure via baby teeth, revealing impacts on brain development and behavior in children and adolescents.

30 Apr 2026

Baby teeth reveal early metal exposure effects on brain

Researchers at the Icahn School of Medicine at Mount Sinai report that early-life exposure to common environmental metals may influence brain development and behavioral health more than a decade later.

25 Apr 2026

Novel catalytic approach accelerates synthesis of branched drug compounds

When chemists design drug candidates, shape matters enormously. Many active pharmaceutical ingredients contain branched carbon structures-points where the molecular chain forks in a specific direction-that are critical to whether a molecule will bind to its biological target and whether it will be safe.

9 Apr 2026

New MRI method tracks transplanted heart stem cells for months

Researchers at the Institute of Biomedical Engineering at the University of Toronto have demonstrated a new way to monitor transplanted stem-cell-derived heart cells using magnetic resonance imaging (MRI).

8 Apr 2026

Newly developed smart molecules offer a safer and more precise approach to cancer care

Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care.

7 Apr 2026

Air pollution may be lowering global IQ and widening inequality, researchers warn

Researchers argue that exposure to fine particulate air pollution (PM2.5) may affect cognitive function and intelligence, potentially causing large population-level losses in global IQ. Using modelling based on published exposure–response data, the authors estimate that pollution could be associated with tens of billions of IQ points lost worldwide, with the largest impacts in lower-income regions.

10 Mar 2026