Nephropathy News and Research

RSS

Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Kidney Week 2026 features late-breaking clinical trials in kidney care

The American Society of Nephrology, has selected the following late breaking clinical trials to be presented in-person at Kidney Week 2026 October 22–25.

24 Oct 2026

Longer sleep duration linked to diabetic kidney disease risk

People with type 2 diabetes who sleep longer may have an increased risk of developing or worsening existing diabetic kidney disease, according to a study published in the Journal of the Endocrine Society.

8 Oct 2026

Researchers found a curious mitochondrial pattern in people who moved more

Researchers found that greater self-reported activity, walking, and accelerometer-measured light activity were associated with higher mitochondrial DNA copy number in 256 healthy middle-aged adults. The cross-sectional findings cannot establish causation, and the very low amount of vigorous activity means they do not show that light movement is more beneficial than higher-intensity exercise.

29 Sep 2026

Insilico Medicine launches AI initiative to develop longevity vaccines

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced Longevity Vaccines, a research initiative developing treatments that direct a patient's own immune cells to eliminate the earliest cellular drivers of age-related disease.

15 Sep 2026

Gestational diabetes history linked to earlier development of type 2 diabetes

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that, in women that develop type 2 diabetes (T2D), those who had gestational diabetes (GD) when pregnant are developing T2D on average almost 13 years earlier than those who did not.

3 Sep 2026

Study links oxalate to systemic inflammation and heart damage

Oxalic acid might do more than just contribute to the formation of kidney stones — it may also be an underappreciated driver of inflammation and heart damage in people with impaired kidney function.

11 Jul 2026

Okra supplements may lower cholesterol and inflammation markers in diabetes

...

29 Jun 2026

Air pollution linked to rising kidney disease hospitalization risks

A study supported by FAPESP and published in the journal Scientific Reports showed a strong correlation between the concentration of particulate matter in the air of São Paulo, Brazil – primarily emitted by vehicle fuel combustion – and kidney disease.

13 May 2026

Asthma medication formoterol shows promise for treating fatty liver disease

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide.

8 May 2026

CFHR1 could be a new diagnostic marker for IgA nephropathy

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced extracellular matrix production, and variable infiltration of inflammatory cells.

30 Mar 2026

BNP predicts kidney disease progression risk in diabetes patients

The relationship between cardiovascular dysfunction and renal impairment is widely recognized as the cardiorenal interaction, a complex physiological link in which damage to one organ can accelerate deterioration in the other.

24 Mar 2026

New strategy to fight chronic kidney inflammation

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells – also known as "zombie cells" – in diabetic kidney disease.

10 Mar 2026

Combination therapy can reduce harmful effects of senescent cells in diabetic kidney disease

5 Mar 2026

MERLIN algorithm unlocks immune cell location memory in organs

A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually.

2 Mar 2026

Role of food nutrients in reducing oxidative stress linked to micro- and nanoplastics

This narrative review examines how micro- and nanoplastics may contribute to oxidative stress, inflammation, and metabolic dysfunction, including potential links with diabetes. It highlights plant-derived nutrients that activate the Nrf2 pathway as a possible strategy to enhance cellular stress resilience, although most evidence remains preclinical.

15 Feb 2026

Diabetic nephropathy shows severe biochemical abnormalities

Chronic diabetes mellitus is marked by hyperglycemia and metabolic dysfunction, increasing the risk of complications such as nephropathy.

13 Feb 2026

Simple fruit granola intervention shows promising cardio-renal signals in CKD patients

A single-arm intervention study in Japanese adults with moderate chronic kidney disease found that replacing breakfast with fruit granola for two months lowered systolic blood pressure, reduced LDL-related lipid markers, and decreased a urinary marker of tubular injury. Renal function remained stable, bowel habits improved, and findings were exploratory due to the small, open-label design.

21 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

GLP-1 receptor agonists improve glycaemic control and provide renal, metabolic, and selective cardiovascular benefits in people with type 2 diabetes, based on an umbrella review of 17 meta-analyses. However, these agents consistently increase gastrointestinal adverse effects and show important distinctions between class-level outcomes and individual drug effects, particularly for semaglutide.

20 Nov 2025

EULAR develops new disease activity score for antiphospholipid syndrome

EULAR - The European Alliance of Associations for Rheumatology - has developed a new disease activity score that quantifies the level of disease activity in people with antiphospholipid syndrome (APS).

19 Nov 2025