Prion News and Research

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Novel blood-based method diagnoses Alzheimer’s disease with high accuracy

Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain.

25 Aug 2026

Study sheds light on the prognostic value of blood test for predicting cognitive impairment risk

A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a cognitively healthy individual will go on to develop cognitive impairment-a key symptom of Alzheimer's disease.

15 Jul 2026

AI discovers hidden antibiotic candidates inside disease-causing prions

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

19 Jun 2026

Researchers track how chronic wasting disease spreads to other species

Chronic wasting disease (CWD) is generally associated with animals. But a new study by researchers from the University of Calgary and international collaborators explored the potential for CWD to spread from deer, elk and other cervid (hooved, plant-eating) animals to other species.

11 Jun 2026

Can collagen supplements really improve your skin?

Investigating collagen peptides, this review explores their role in skin aging, assessing clinical evidence and the mechanisms behind their potential benefits.

25 Mar 2026

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025

Synthetic tau protein reveals key insights into protein misfolding and fibril formation

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion.

29 Apr 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

New algorithm enhances prediction of disordered protein structures

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging.

7 Mar 2025

New gene-editing treatment extends lifespan in mice with prion disease

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Vanderbilt researchers achieve milestone in Alzheimer's drug development

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and schizophrenia.

19 Dec 2024

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models

Researchers find that Semaglutide improves cognitive function and reduces amyloid and tau pathology in Alzheimer's disease models, while restoring oxytocin levels in both mice and human brain organoids.

14 Oct 2024

Cap-QuIC: A new visual diagnostic technique for early detection of neurodegenerative diseases

Researchers at the University of Minnesota, have developed a new visual diagnostic technique that can be used to advance early detection for neurodegenerative diseases like Parkinson's disease and similar diseases that affect animals, including Chronic Wasting Disease in deer.

6 Aug 2024

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Researchers developed an AI model using multimodal data to accurately diagnose different types of dementia, enhancing early and personalized treatment.

8 Jul 2024

CHARMs: A new hope for prion disease therapy

Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades.

27 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Prion News and Research

Novel blood-based method diagnoses Alzheimer’s disease with high accuracy

Study sheds light on the prognostic value of blood test for predicting cognitive impairment risk

AI discovers hidden antibiotic candidates inside disease-causing prions

Researchers track how chronic wasting disease spreads to other species

Can collagen supplements really improve your skin?

Research shows how lysosomes respond to stress

Synthetic tau protein reveals key insights into protein misfolding and fibril formation

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

New algorithm enhances prediction of disordered protein structures

New gene-editing treatment extends lifespan in mice with prion disease

Vanderbilt researchers achieve milestone in Alzheimer's drug development

Metagenomic sequencing improves detection of rare pathogens in CNS infections

Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models

Cap-QuIC: A new visual diagnostic technique for early detection of neurodegenerative diseases

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

CHARMs: A new hope for prion disease therapy

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Mammal-specific domain of the prion protein may hold clues to neurodegenerative diseases

Study confirms strong barrier preventing chronic wasting disease transmission to humans

Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

Microbiology eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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