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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cancer-related DNA changes may appear in blood years before diagnosis

Researchers found that genome-wide plasma cfDNA methylation profiles collected before diagnosis contained early molecular signatures associated with future prostate and breast cancer, with prostate silencer methylation providing the stronger risk stratification. Breast enhancer signals were weaker and varied by subtype and disease stage, indicating that cfDNA methylation may have greater value for risk assessment and surveillance than as a standalone diagnostic test.

23 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

Higher ultra-processed food intake linked to multiple health risks

A higher ultra processed food (UPF) intake is linked to a heightened risk of several major chronic health issues, such as digestive diseases, high blood pressure, and metabolic syndrome/diabetes, as well as death, finds a pooled data analysis of the available evidence, published in the open access journal Family Medicine and Community Health.

22 Sep 2026

C-Path awards $1.7 million to advance five drug development projects

Critical Path Institute (C-Path) today announced that its Translational Therapeutics Accelerator has awarded $1,699,500 through five Bridging Research and Innovation in Drug Development Grants (BRIDGe).

22 Sep 2026

MLC1 auto-antibodies identified as possible trigger for NMOSD-like diseases

NMOSD is an inflammatory autoimmune disorder that damages support and supply cells in the central nervous system, known as astrocytes.

22 Sep 2026

City of Hope develops adaptive plug-and-play CAR T technology to attack tumors

Researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the country, have developed a new "plug-and-play" technology that adds engineered molecules to chimeric antigen receptor (CAR) T cells after treatment, allowing scientists to better control the cells and redirect them to attack different types of cancer.

22 Sep 2026

The FFS (Fight Fibrin Sheath) campaign launches to improve patient lives by tackling dialysis catheters' most common dysfunction

An international coalition of vascular access surgeons, nephrologists, researchers and industry partners today launched the Fight Fibrin Sheath (FFS) campaign, a clinician-led action group working collaboratively to advance research, education and innovation relating to fibrin sheath formation, and to improve vascular access outcomes for dialysis patients worldwide.

22 Sep 2026

Submicron IR for pharmaceutical research, development, and quality

The pharmaceutical and biopharmaceutical industries increasingly require rapid, accurate, and high-resolution analytical tools to characterize complex materials, ensure product quality, and accelerate innovation.

From Photothermal Spectroscopy Corp 22 Sep 2026

Chronic DNA damage response may contribute to biological aging

A new review was published in Volume 18 of Aging on August 31, 2026, titled "The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework."

21 Sep 2026

Roundworm study uncovers cellular effects of kidney disease mutation

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

21 Sep 2026

Researchers identify a rare genetic change linked to neurodevelopmental disorder

Research led by Texas Children's Duncan Neurological Research Institute (Duncan NRI) and Baylor College of Medicine identified a rare genetic change that appears to cause a newly recognized neurodevelopmental disorder.

21 Sep 2026

KAUST researchers develop AI tool to map cell evolution

Publishing in Nature Communications, a KAUST-led team has developed the AI tool Unify to help scientists compare similar cell types across distant species.

21 Sep 2026

Cohesin protein protects genetic information during cell division

Cell division, a process fundamental to life, still holds surprises. Researchers from the University of Zurich and the Spanish National Cancer Research Centre (CNIO) have discovered a key mechanism that allows cells to protect genetic information as they divide.

21 Sep 2026

German researchers aim to completely degrade breast cancer protein

Simply switching off a protein that helps breast cancer cells to grow? That is not enough for researchers at the University of Duisburg-Essen.

21 Sep 2026

Active form of meprin-β protein increases in people with Alzheimer’s disease

A team from the Altered Molecular Mechanism in Alzheimer's Disease and Dementia laboratory, led by Javier Sáez Valero, a researcher at the Institute for Neurosciences (IN), a joint centre of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), has identified increased levels of the protein meprin-β in the brain and cerebrospinal fluid of people with Alzheimer's disease.

21 Sep 2026

Study reveals how CaMKIIα proteins organize during memory formation

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University, Kyoto University, SOKENDAI, and the National Institute for Physiological Sciences have revealed how CaMKIIα-a key brain protein involved in learning and memory-organizes itself into chain-like structures.

20 Sep 2026