Pulmonary Artery News and Research

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Catheter-directed thrombolysis improves short-term outcomes in pulmonary embolism patients

In patients with intermediate−high risk pulmonary embolism, catheter-directed thrombolysis improved short-term clinical outcomes compared with standard anticoagulation therapy alone, according to results presented in a Hot Line session today at ESC Congress 2026.

31 Aug 2026

New study makes progress in understanding the mechanisms behind severity of HFpEF

Approximately 3 million people in the United States are living with a condition called heart failure with preserved ejection fraction, or HFpEF.

24 Aug 2026

Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

23 Jul 2026

Microbially modified bile acids influence sleep apnea outcomes

Studies in mice reveal a new target for potentially treating and preventing life-threatening cardiovascular complications in the millions of patients with sleep apnea worldwide.

7 Jun 2026

Early paracetamol may speed up heart vessel closure in preterm babies

Early administration of paracetamol may accelerate closure of the patent ductus arteriosus in extremely preterm babies, according to a new study.

3 Jun 2026

Intense light therapy reduces hypoxia-induced heart damage in mice

Right ventricular (RV) remodeling and dysfunction are serious cardiovascular consequences due to prolonged hypoxic exposure, commonly seen in conditions such as chronic lung disease and high-altitude environments.

10 Apr 2026

New drug sotatercept shows benefit in CpcPH-HFpEF patients

Patients who have heart failure with preserved ejection fraction (HFpEF) and high blood pressure in the lungs (pulmonary hypertension) experienced significant improvements in blood pressure and vascular health after taking the drug sotatercept, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Major trial questions the need for invasive monitoring in heart surgery

Australians undergoing open-heart surgery could soon benefit from safer, simpler care and get home earlier thanks to the results of a world-first clinical trial led by Monash University's Victorian Heart Institute.

21 Jan 2026

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

AI-powered ECG model outperforms doctors in detecting hidden heart disease

Researchers developed an AI-powered ECG model, EchoNext, that detects structural heart disease with high accuracy across diverse hospitals and patient populations. The model outperformed cardiologists and could identify thousands of undiagnosed cases, potentially transforming cardiac screening.

21 Jul 2025

How five months in Tibet changed the heart and lungs of Beijing workers

Long-term exposure to very high altitude significantly reduces cardiopulmonary function in healthy adults from lowland regions, as shown by declines in aerobic capacity and efficiency after five months in Lhasa, China.

13 Jul 2025

New screening tool enhances early detection of pulmonary hypertension

A novel screening approach developed by physicians at the Lewis Katz School of Medicine at Temple University shows significant promise for improving the detection of pulmonary arterial hypertension (PAH)-a life-threatening form of heart failure related to high blood pressure in the lung circulation that is often overlooked due to vague symptoms such as fatigue and shortness of breath.

4 Jun 2025

Study highlights pulmonary artery denervation as a key intervention for pulmonary hypertension

A recent publication in the International Journal of Cardiology, Pulmonary artery denervation in pulmonary hypertension: A comprehensive meta-analysis, has shed light on the potential of pulmonary artery denervation (PADN) as an innovative intervention for pulmonary hypertension (PH), a condition that places patients at risk for right heart failure and death.

8 Apr 2025

Study reveals best treatment strategy for high-risk pulmonary embolism

A current study involving the University Hospital Bonn (UKB) has investigated which treatment strategy offers the best chances of survival in high-risk acute pulmonary embolism.

4 Mar 2025

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

21 Aug 2024

Study reveals benefits of hormone replacement therapy in female pulmonary hypertension patients

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference. Pulmonary hypertension (PH) is a type of pulmonary vascular disease - disease that affects blood vessels along the route between the heart and lungs.

20 May 2024