Synovitis News and Research

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GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Early clinical events predict disease progression in very early systemic sclerosis

The VEDOSS project has previously shown that 70% of patients with Raynaud's phenomenon and at least one red flag – systemic sclerosis (SSc)-specific antibodies, puffy fingers, or an SSc pattern on nailfold capillaroscopy –will fulfil the 2013 ACR/EULAR SSc criteria within 5 years.

13 Jun 2025

Current state and future prospects of artificial ligaments for treating ACL injuries

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

14 Mar 2025

Artificial ligaments could revolutionize ACL surgery and recovery

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

27 Feb 2025

Vimseltinib gains FDA approval for treating tenosynovial giant cell tumor

The U.S. Food and Drug Administration (FDA) has approved vimseltinib (RomvimzaTM) for adult patients with a rare condition called tenosynovial giant cell tumor (TGCT). TGCT is a tumor of the tissue that lines the joints.

20 Feb 2025

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Researchers assessed cognitive function among rheumatoid arthritis patients with ongoing inflammatory activity.

1 Aug 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

New treatment option for hand osteoarthritis identified

Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment.

12 Oct 2023

AI interpretations of MRI images could provide more accurate RA prediction

Early inflammatory arthritis is often undifferentiated, but it may develop into established RA or another arthropathy.

31 May 2023

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Researchers examined the therapeutic potential of ARA 3,000 BETA for treating osteoarthritis.

16 May 2023

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time, according to a new study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

Total body PET/CT scans can effectively visualize systemic joint involvement in patients with arthritis

Total body PET/CT scans can successfully visualize systemic joint involvement in patients with autoimmune arthritis, according to new first-in-human research published in the October issue of The Journal of Nuclear Medicine.

14 Oct 2022

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

At this year's American College of Rheumatology virtual meeting, Hospital for Special Surgery (HSS) presented exciting research related to rheumatology and orthopedic surgery.

10 Nov 2020

Case report of arthritis in a COVID-19 patient

The current paper published in the The Lancet Rheumatology discusses arthritis in a 58-year-old white woman with COVID-19 of less than severe intensity.

7 Oct 2020

Thermal imaging has potential to assess rheumatoid arthritis

A new study, published today in Scientific Reports, highlights that thermal imaging has the potential to become an important method to assess Rheumatoid Arthritis.

25 Nov 2019

Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis.

11 Nov 2019

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis.

11 Nov 2019

Conditions that produce signs similar to arthritis

Arthritis is a term commonly used to describe conditions giving rise to joint based symptoms. Arthritis takes on many forms, with osteoarthritis and rheumatoid arthritis among the most common.

15 Nov 2018

Individuals with synovitis may have greater risk for cartilage damage, shows study

In an Arthritis & Rheumatology study of 221 patients with knee osteoarthritis and meniscal tears, increases in inflammation of the synovial membrane--whether persistently extensive or intermittent--were linked with cartilage damage over time.

22 Aug 2018

Synovitis News and Research

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Early clinical events predict disease progression in very early systemic sclerosis

Current state and future prospects of artificial ligaments for treating ACL injuries

Artificial ligaments could revolutionize ACL surgery and recovery

Vimseltinib gains FDA approval for treating tenosynovial giant cell tumor

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Omega-3 supplements show promise in battling osteoarthritis

New treatment option for hand osteoarthritis identified

AI interpretations of MRI images could provide more accurate RA prediction

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Total body PET/CT scans can effectively visualize systemic joint involvement in patients with arthritis

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

Case report of arthritis in a COVID-19 patient

Thermal imaging has potential to assess rheumatoid arthritis

Methotrexate reduces joint damage in hand osteoarthritis

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

Conditions that produce signs similar to arthritis

Individuals with synovitis may have greater risk for cartilage damage, shows study

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