Tetanus News and Research

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Tetanus is a severe, frequently fatal disease caused by an exotoxin produced by Clostridium tetani, a bacterium that is found in the environment. Tetanus is not transmitted from person to person. Rather, Clostridium tetani enters the body through an open wound, including lacerations, abrasions and puncture wounds. The toxin causes neuromuscular dysfunction, with rigidity and spasms of skeletal muscles. The muscle spasms usually start in the jaw (which is why the disease is sometimes called "lockjaw") and neck and may spread to many other muscles, leading to generalized paralysis.

A 194-country analysis reveals gaps in how late childhood vaccinations are tracked

A global analysis of WHO/UNICEF data from 194 countries found wide variation in countries’ ability to record delayed childhood vaccinations, with 64% of reporting countries saying they could capture late doses in 2022. Following birth cohorts over time and adding delayed MCV1 doses raised median coverage estimates by 3.6 to 5.1 percentage points across available cohort years, though incomplete and inconsistent reporting limited confidence in some estimates.

21 Sep 2026

The US switch in shingles vaccines revealed an unexpected heart health pattern

In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic studies

27 Aug 2026

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

27 Aug 2026

New review examines why tetanus remains a global health problem

Tetanus is often considered a disease of the past, remembered mainly through childhood vaccinations and warnings about rusty nails.

20 Aug 2026

Why pregnancy vaccination looks very different in Germany than it did 19 years ago

A 19-year German claims analysis of more than 2.8 million pregnancies found that recorded maternal vaccination increased substantially after national recommendations for influenza and pertussis immunization were introduced. Influenza vaccination reached 19.4% and pertussis vaccination about 37% in 2020-2022, while COVID-19 vaccination was not captured in the databas

19 Aug 2026

New optical control platform blocks and restores neural signaling

DGIST (President Kunwoo Lee) announced that a research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, in collaboration with a research team led by Professor Alice Ting at Stanford University, has developed LATeNT, a novel optical control platform that uses light to block signal transmission between neurons and subsequently restore normal signaling.

19 Aug 2026

Pregnant women use Reddit to seek Tdap vaccine reassurance

An analysis of Reddit posts about the maternal Tdap vaccine made by pregnant women reveals expectant mothers turning to Reddit to seek advice and reassurance-with fewer outright instances of vaccine hesitation/refusal than has generally been observed for other types of vaccines, according to a study published on August 12, 2026 in the open access journal PLOS Global Public Health by Soojung Jo from Purdue University, United States, and colleagues.

12 Aug 2026

Fridge-free vaccine shows promise for reaching millions more people worldwide

The world-first trial of a fridge-free tetanus-diphtheria vaccine at University Hospital Southampton (UHS) has produced encouraging results that could improve access worldwide to crucial treatments.

10 Aug 2026

Survey finds widespread uncertainty over pregnancy vaccine recommendations

Most Americans are unaware or unsure of which vaccines the Centers for Disease Control and Prevention (CDC) recommends during pregnancy, according to a nationally representative survey of U.S. adults by the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

22 Jul 2026

Global child immunization rates stall despite minor pandemic recovery

In 2025, 90% of infants globally – or nearly 116 million – received at least one dose of a diphtheria, tetanus and pertussis (DTP) vaccine, and 85% – or 110 million – completed the full three-dose series, according to the annual WHO-UNICEF Estimates of National Immunization Coverage (WUENIC) released today.

15 Jul 2026

Machine learning boosts medicine access in resource-limited healthcare settings

Managing a medical supply chain in low- and middle-income countries can mean navigating a landscape prone to extreme and unexpected disruptions.

2 Jul 2026

Young adults miss health benefits by neglecting primary care doctors

A new survey commissioned by The Ohio State University Wexner Medical Center finds young adults are missing out on the health benefits of having a primary care doctor.

29 Jun 2026

Extensive data analysis confirms the safety of aluminum adjuvanted vaccines

Current evidence does not support direct (causal) associations between aluminium adjuvanted vaccines and serious or long-term health outcomes, including autism, diabetes, and asthma, finds a review of the latest data published by The BMJ today.

7 May 2026

Study suggests shingles vaccine may help lower Alzheimer’s and dementia risk

A large observational electronic health record study found that older adults receiving the recombinant zoster vaccine showed substantially lower rates of diagnosed dementia compared with matched unvaccinated individuals. The association persisted after multiple sensitivity analyses, although causality remains unproven and longer follow-up is required given the long latency of dementia.

10 Feb 2026

Vaccines are helping older people more than we knew

Let's be clear: The primary reason to be vaccinated against shingles is that two shots provide at least 90% protection against a painful, blistering disease that a third of Americans will suffer in their lifetimes, one that can cause lingering nerve pain and other nasty long-term consequences.

14 Jan 2026

Maternal whooping cough vaccine shields newborns' immune system

In 2024, Germany recorded the highest number of whooping cough cases since reporting became mandatory in the year 2013.

9 Jan 2026

The CDC just sidelined these childhood vaccines. Here’s what they prevent.

The federal government has drastically scaled back the number of recommended childhood immunizations, sidelining six routine vaccines that have safeguarded millions from serious diseases, long-term disability, and death.

6 Jan 2026

Whooping cough cases rise sharply across the United States

Pertussis, also known as whooping cough, is a vaccination-preventable illness that has been on the rise in the United States. Following a several-year lull during the pandemic, cases of whooping cough rose sixfold in 2024 and remain high.

18 Dec 2025

In RFK Jr.’s upside-down world of vaccines, panel votes to end hepatitis B shot at birth

Recent weeks have brought good news about vaccines, with studies indicating that flu vaccination reduces heart disease, shingles vaccines can prevent or slow dementia, and a single human papilloma virus shot protects a girl from cervical cancer for the rest of her life.

5 Dec 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025