Vulva News and Research

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The vulva is the external genital organs of the female. In colloquial speech, the term ''vagina'' is often wrongly used to refer to the female genitals generally. The vagina is a specific internal structure, whereas the vulva is the whole exterior genitalia.

Review outlines key strategies to reduce gynecologic cancer-related mortality

Low- and middle-income countries (LMICs) bear a disproportionate burden of gynecologic malignancies-cancers of the cervix, endometrium, ovary, vagina, and vulva.

24 Aug 2026

Phase 3 clinical trial enrolls first platinum-resistant ovarian cancer patient

The GOG Foundation, Inc. is proud to announce the enrollment of the first patient in GOG-3132/BEHOLD-Ovarian01 (NCT07286266), a global Phase 3 clinical trial titled A Randomized, Open-label, Multicenter, Phase 3 Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants with Platinum-resistant Ovarian Cancer.

27 Jul 2026

New nonhormonal therapy shows promise for treating Genitourinary Syndrome of Menopause

Researchers at the University of Colorado Anschutz have developed a promising nonhormonal therapy for women experiencing Genitourinary Syndrome of Menopause (GSM).

7 Jul 2026

HPV vaccination reduces risk of vulvar and vaginal lesions

Girls who are vaccinated against HPV are not only well protected against cervical cancer; they are also less likely to develop severe precancerous lesions of the vulva and vagina, particularly if they were vaccinated before the age of 17.

18 Dec 2025

New study could lead to quicker and more targeted support for vulvodyniaia

A first-of-its-kind University of Stirling-led study could lead to quicker and more targeted support for vulvodynia - a painful chronic condition estimated to affect more than one in 10 women with no known cause.

9 Dec 2025

New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer

Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.

24 Nov 2025

Unusual presentation of vulvar mucinous cyst with multiple bartholin cysts in a reproductive-age woman

A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Vulvar mucinous cyst mimicking common lesions with concurrent multiple bartholin cysts in a reproductive-age woman: A rare case report and review of literature."

30 Oct 2025

Regular sexual activity can reduce problematic menopause symptoms, study suggests

It's no secret that women often become less interested in sex with age. However, orgasm and satisfaction have been shown to not decline significantly with age.

25 Jun 2025

Mass General Brigham researchers share cancer research discoveries at ASCO 2025

Researchers from Mass General Brigham will present research discoveries and outcomes from clinical trials in cancer at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, held May 30-June 3, in Chicago.

30 May 2025

Testosterone use not linked to increased gynecological cancer risk in early years

Transmasculine and gender-diverse individuals who use testosterone are not at increased risk of gynecological cancer in the first years of hormone therapy.

12 May 2025

Online resource launched to empower people with vulval lichen sclerosus

A new online guide has launched to support and empower people with vulval lichen sclerosus (LS) to learn about the condition, access the right treatment and live more comfortably.

21 Jan 2025

Research identifies 31 additional cancers potentially linked to obesity

This research identifies 18 potential obesity-related cancers, revealing significant associations with BMI and underscoring obesity's impact on cancer risk.

22 Aug 2024

Lateral episiotomy reduces risk of severe perineal trauma in first-time mothers

In first-time mothers requiring vacuum-assisted delivery, a lateral episiotomy (angled cut) in the tissue between the vaginal and anal opening more than halves the risk of obstetric anal sphincter injury, a severe form of perineal trauma between the vulva and anus.

18 Jun 2024

The role of cellular or cytokine response and vaginal microbiome dysbiosis in the clearance, persistence, and recurrence of HPV infection

Researchers have reviewed the role of cytokine or cellular response and vaginal microbiome dysbiosis in the persistence, clearance, and recurrence of HPV infection

28 Jul 2022

Genital dissatisfaction more prevalent in general population than expected according to new Swedish survey

A new study depicted that the genital self-image and satisfaction with one’s genitalia were generally low among Swedish men and women and genital size was not the only influencing factor for self-impression.

20 Jul 2022

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Four international medical societies have collaborated on consensus statements for physicians, published in the Journal of Lower Genital Tract Disease, about how to treat pre-invasive lesions of the vulva.

21 Jun 2022

Researchers highlight the need to address sexual health problems in women with type 1 diabetes

Sexual problems are a well-documented complication of diabetes in men. But research on how women's sexuality is affected by different types of diabetes is very limited, find Swedish researchers in a new publication.

15 Dec 2021

Trial positions single-dose HPV vaccination as a high impact public health intervention

In the push to eliminate cervical cancer, researchers delivered hopeful news Nov. 17 at the 34th International Papillomavirus Conference in Toronto.

20 Nov 2021

Researchers discover unique self-destructive process in aging nematode worms

As worm mothers age, they secrete a milk-like fluid through their vulva that is consumed by their offspring and supports their growth, according to a new study led by UCL researchers.

6 Oct 2021

Mount Sinai awarded more than $4 million to evaluate anal cancer screening in high-risk women

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million by the National Cancer Institute for a large-scale study to evaluate anal cancer screening in high-risk women who have been previously diagnosed with human papillomavirus (HPV) infection.

10 Aug 2021