Cell Biology

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RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

Two clever human antibodies can target Ebola and Sudan virus

Researchers at La Jolla Institute for Immunology (LJI) are designing better therapies for treating Ebola virus and its deadly relatives.

17 Mar 2022

Study explores profiles of COVID-19 vaccines across different countries

A new study analyzed the amplitude, time, and adverse events associated with COVID-19 vaccines across different countries.

17 Mar 2022

Optical coherence tomography reveals the beating and development of human heart organoids

Researchers have been using organoids - 3D organ-like, tightly-packed cell cultures - as models to study organ development, disease and drug discovery with excellent success.

16 Mar 2022

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Individual Candida albicans yeast strains in the human gut are as different from each other as the humans that carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study from researchers at Weill Cornell Medicine.

16 Mar 2022

Yale researchers uncover how to control the blood-brain barrier with a molecule

The brain is composed of billions of neurons - vulnerable cells that require a protective environment to function properly.

16 Mar 2022

Pressure drives sudden burst of rapid and coordinated cellular motion in 3D tumor model

Biological processes such as wound healing and cancer cell invasion rely on the collective and coordinated motion of living cells.

16 Mar 2022

New insight into how gut bacteria work to counter intestinal inflammation

Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.

16 Mar 2022

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

Some "hypervirulent" strains of Listeria monocytogenes have a greater capacity to infect the central nervous system.

16 Mar 2022

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Scientists from Nanyang Technological University, Singapore have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

16 Mar 2022

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can have damaging effects over the medium and long term.

16 Mar 2022

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

The coming of spring harkens spring cleaning; a time to de-clutter your home and discard things that are no longer needed. In the body, a cellular process called autophagy occurs regularly to "de-clutter" our cells.

15 Mar 2022

Orally-active senolytics can boost a key beneficial protein in mice and humans

Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases.

15 Mar 2022

Study takes a new approach to looking at de novo genetic variants in autism

About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA contributes to the development of ASD has been more of a mystery.

15 Mar 2022

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat retinal damage and visual impairment, according to the findings of a new study published in the journal eBioMedicine.

15 Mar 2022

Immune cells could help predict the prognosis of patients with ALS

Immune cells could help predict the prognosis of patients with the rare neurological disease amyotrophic lateral sclerosis (ALS), says a study published today in eLife.

15 Mar 2022

Study finds elevated inflammation in macrophages months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

Detailed molecular map of stratum corneum can help develop new skin treatments

Scientists have accurately analyzed the tough barrier layer of the skin giving the most detailed molecular map of its structure that will help in the development of new skin products and treatments.

14 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Researchers find unusual way of stabilizing cancer-suppressing protein

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilizing the protein and making it more potent.

14 Mar 2022

Cell Biology

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Two clever human antibodies can target Ebola and Sudan virus

Study explores profiles of COVID-19 vaccines across different countries

Optical coherence tomography reveals the beating and development of human heart organoids

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Yale researchers uncover how to control the blood-brain barrier with a molecule

Pressure drives sudden burst of rapid and coordinated cellular motion in 3D tumor model

New insight into how gut bacteria work to counter intestinal inflammation

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

Orally-active senolytics can boost a key beneficial protein in mice and humans

Study takes a new approach to looking at de novo genetic variants in autism

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Immune cells could help predict the prognosis of patients with ALS

Study finds elevated inflammation in macrophages months after mild COVID-19

Detailed molecular map of stratum corneum can help develop new skin treatments

Using mRNA to introduce gene editor into human muscle stem cells

Researchers find unusual way of stabilizing cancer-suppressing protein

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Synthetic Biology and the Pursuit of Living Diagnostics

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