Cell Biology

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New model reveals how antibodies navigate pathogen surfaces like a child at play

A new study shows how antibodies select the antigens that they bind to, as they navigate the surface of pathogens like coronaviruses.

24 Mar 2022

Tuberculosis perturbs epigenetic processes to promote premature cellular aging

Tuberculosis (TB) is a potentially serious infectious disease caused by a type of bacterium called Mycobacterium tuberculosis.

24 Mar 2022

Powerful new Cytobank platform upgrade available from Beckman Coulter Life Sciences

Building on its legacy of providing labs with better solutions for analysis, management, and sharing of complex flow and mass cytometry data, Beckman Coulter Life Sciences announces a series of updates to its Cytobank platform.

From Beckman Coulter Life Sciences - Flow Cytometry 24 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

People who consume sugar for extended periods have increased risk of autoimmune disease

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

23 Mar 2022

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer.

23 Mar 2022

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

Leicester researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.

23 Mar 2022

Investigators create specialized, tissue-like structures to model barrier tissues

Investigators at the Brigham and the Broad Institute have created specialized, tissue-like structures in the laboratory to model barrier tissues, such as the intestines, to identify new targets for treatment. Barrier tissues are exposed to substances from the outside world but serve as a layer of protection.

23 Mar 2022

Quantum dots can quantify specific types of cells inside deep tissues of the body

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency.

22 Mar 2022

Function of glycolytic enzyme depends on its cellular localization

The function of the glycolytic enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study published in Molecular Cell.

22 Mar 2022

Researchers identify a protein that protects against breast cancer growth

Researchers at Karolinska Institutet in Sweden have identified a protein that protects against breast tumor growth and that can be linked to a better prognosis in breast cancer patients.

22 Mar 2022

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and controllable method to convert pluripotent stem-cells into bona fide 8-cell totipotent embryo-like cells, paving the way for advances in organ regeneration and synthetic biology.

22 Mar 2022

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem - a failsafe that is critical to maintaining health and staving off disease.

22 Mar 2022

New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

A single gene can control brain cell growth in humans, research shows

Controlling how cells grow is fundamental to ensuring proper brain development and stopping aggressive brain tumors.

19 Mar 2022

Scientists generate an atlas of human and mouse white adipocytes

Once considered to be inert, white adipose tissue is now recognized to be dynamic and to play an interactive role in a wide array of biological and metabolic processes.

18 Mar 2022

New method for generating lung tissue from just a few body cells in the lab

Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg's Faculty of Medicine have succeeded in collaboration with American researchers in generating tiny quantities of lung tissue, so-called organoids, from just a few body cells in the lab.

18 Mar 2022

Cell Biology

New model reveals how antibodies navigate pathogen surfaces like a child at play

Tuberculosis perturbs epigenetic processes to promote premature cellular aging

Powerful new Cytobank platform upgrade available from Beckman Coulter Life Sciences

New therapy makes immunologically 'cold' tumors hot enough for immune attack

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

People who consume sugar for extended periods have increased risk of autoimmune disease

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

Investigators create specialized, tissue-like structures to model barrier tissues

Quantum dots can quantify specific types of cells inside deep tissues of the body

Scientists identify a promising strategy for stopping Ebola virus polymerase

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

Function of glycolytic enzyme depends on its cellular localization

Researchers identify a protein that protects against breast cancer growth

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

New computational approach creates spatial maps of single-cell data within tissues

A single gene can control brain cell growth in humans, research shows

Scientists generate an atlas of human and mouse white adipocytes

New method for generating lung tissue from just a few body cells in the lab

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