Cell Biology

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T cells can be engineered to fight tumors without succumbing to exhaustion

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.

19 Jul 2021

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

The second dose of a COVID-19 vaccine induces a powerful boost to a part of the immune system that provides broad antiviral protection, according to a study led by investigators at the Stanford University School of Medicine.

19 Jul 2021

Central amygdala micro-circuits play active role in regulation of fear responses

The brain mechanisms underlying the suppression of fear responses have attracted a lot of attention as they are relevant for therapy of human anxiety disorders.

16 Jul 2021

Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

Researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

16 Jul 2021

New method shows how fatty acids are absorbed by single cells

A new method developed by Institute for Systems Biology and University of California, Riverside provides new insights into cancer biology by allowing researchers to show how fatty acids are absorbed by single cells.

16 Jul 2021

Study uncovers how force dynamics affect cells and living tissues

Researchers, led by Pere Roca-Cusachs at the Institute for Bioengineering of Catalonia (IBEC) discover how force dynamics affect cells, and living tissues. The results give an insight into the critical mechanical processes that occur in different diseases such as cancer.

16 Jul 2021

RUDN University biologists discover the way how macrophages respond to inflammation

RUDN University biologists discovered the way how macrophages (the cells of the "first line" immune response) respond to inflammation and identified how the immune response depends on their origin.

16 Jul 2021

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Computer simulation model identifies key factors for successful transit of sperm in the genital tract

A research team at the Humboldt University Berlin and the Leibniz Institute for Zoo and Wildlife Research developed an agent-based computer model to simulate the journey of sperm cells through the female genital tract.

16 Jul 2021

New live cell models lay the groundwork for studies into mitochondrial diseases

The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes.

15 Jul 2021

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

T cells are components of the body’s immune system. The ability of T cells to recognize diverse pathogens and mount a defense against them stems from the way proteins are spliced during their development and maturation.

15 Jul 2021

Study reveals key mechanisms of how physical load stimulates bone growth

When things get too much, we're often advised to "take a load off," but when it comes to bone maintenance, doing the opposite can be a good thing. Researchers from Japan have discovered some key mechanisms of how physical load stimulates bone growth.

15 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

Quantum physics helps trigger cancer cell death

Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles.

14 Jul 2021

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Eggs and embryos go through a more dynamic and complex journey than previously thought

The journey of the egg and the embryo through the fallopian tube or oviduct toward the uterus is not well understood, mainly because it is inaccessible for direct imaging.

14 Jul 2021

Research provides an update on how electrical impulses in the heart travel from cell to cell

The rhythm in a working heart is regulated by electrical impulses. Disturbances of this bioelectrical process can result in cardiac arrhythmias, or irregularities in heartbeat -- a common ailment that can lead to illness and death.

13 Jul 2021

Mechanical factors play a key role in the natural growth of human organs

In addition to chemical factors, mechanical influences play an important role in the natural growth of human organs such as kidneys, lungs and mammary glands - but also in the development of tumors.

13 Jul 2021

Understanding the molecular mechanisms behind lung cancer relapse

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away.

13 Jul 2021

Researchers discover new set of signals that control production of goblet cells in the lung

Proper lung function relies on the precise balance of specialized epithelial cells (cells that line the surfaces of the body) that coordinate functions to maintain homeostasis.

13 Jul 2021

Cell Biology

T cells can be engineered to fight tumors without succumbing to exhaustion

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

Central amygdala micro-circuits play active role in regulation of fear responses

Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

New method shows how fatty acids are absorbed by single cells

Study uncovers how force dynamics affect cells and living tissues

RUDN University biologists discover the way how macrophages respond to inflammation

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Computer simulation model identifies key factors for successful transit of sperm in the genital tract

New live cell models lay the groundwork for studies into mitochondrial diseases

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Study reveals key mechanisms of how physical load stimulates bone growth

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Quantum physics helps trigger cancer cell death

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Eggs and embryos go through a more dynamic and complex journey than previously thought

Research provides an update on how electrical impulses in the heart travel from cell to cell

Mechanical factors play a key role in the natural growth of human organs

Understanding the molecular mechanisms behind lung cancer relapse

Researchers discover new set of signals that control production of goblet cells in the lung

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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