Cell Biology

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Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can have damaging effects over the medium and long term.

16 Mar 2022

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

The coming of spring harkens spring cleaning; a time to de-clutter your home and discard things that are no longer needed. In the body, a cellular process called autophagy occurs regularly to "de-clutter" our cells.

15 Mar 2022

Orally-active senolytics can boost a key beneficial protein in mice and humans

Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases.

15 Mar 2022

Study takes a new approach to looking at de novo genetic variants in autism

About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA contributes to the development of ASD has been more of a mystery.

15 Mar 2022

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat retinal damage and visual impairment, according to the findings of a new study published in the journal eBioMedicine.

15 Mar 2022

Immune cells could help predict the prognosis of patients with ALS

Immune cells could help predict the prognosis of patients with the rare neurological disease amyotrophic lateral sclerosis (ALS), says a study published today in eLife.

15 Mar 2022

Study finds elevated inflammation in macrophages months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

Detailed molecular map of stratum corneum can help develop new skin treatments

Scientists have accurately analyzed the tough barrier layer of the skin giving the most detailed molecular map of its structure that will help in the development of new skin products and treatments.

14 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Researchers find unusual way of stabilizing cancer-suppressing protein

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilizing the protein and making it more potent.

14 Mar 2022

Scientists map key molecular changes during mouse embryogenesis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

14 Mar 2022

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms.

14 Mar 2022

Insight into oligodendrocytes in the brain could shed light on the causes of neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis - and autoimmune disease that affects the brain and nervous system - and allow for the development of better therapeutic treatments.

12 Mar 2022

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

Researchers at UC San Diego's Scripps Institution of Oceanography have discovered a novel molecular process that corals use to control the subcellular environment of the algae that live inside them.

11 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

Cell Biology

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

Orally-active senolytics can boost a key beneficial protein in mice and humans

Study takes a new approach to looking at de novo genetic variants in autism

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Immune cells could help predict the prognosis of patients with ALS

Study finds elevated inflammation in macrophages months after mild COVID-19

Detailed molecular map of stratum corneum can help develop new skin treatments

Using mRNA to introduce gene editor into human muscle stem cells

Researchers find unusual way of stabilizing cancer-suppressing protein

Scientists map key molecular changes during mouse embryogenesis

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Insight into oligodendrocytes in the brain could shed light on the causes of neurodegenerative diseases

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

Low profile microplates optimise space utilisation

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

Mechanical stress of confined migration makes cancer cells more aggressive

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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