Cell Biology

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Tufts scientists discover a previously unknown function performed by astrocytes

Researchers at Tufts University School of Medicine have discovered a previously unknown function performed by a type of cell that comprises nearly half of all cells in the brain.

28 Apr 2022

Sleep deprivation negatively affects the stem cells in the cornea

Sleep deprivation, which means getting too little high-quality sleep, is a serious health problem. More than one-third of people in the USA report getting less than the recommended minimum of seven hours sleep per night.

28 Apr 2022

Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

Study shows how DNA changes in Barrett's esophagus cells may predict esophageal cancer

More and more mutations clutter up our DNA as we age. Mostly, these don't cause problems. But sometimes, a switch will flip, and a mutated cell turns cancerous. Can we see this shift in time to prevent or treat cancer before it starts?

28 Apr 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

Eukaryotes emerged in a no-oxygen environment in the ocean, research suggests

The origin of complex cells started without oxygen, new research suggests.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Discovery about human cells’ stress response could deepen the understanding of various cancers

The communications line between two critical parts of a human cell could be the key to cell survival under stress - a discovery that could deepen our understanding of various cancers, according to new research from the University of Surrey.

26 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

UNIGE scientists develop a novel tool to visualize palmitoylation process in living cells

Peripheral membrane proteins have the particularity of temporarily binding to cell membranes, a necessary step for them to be able to fulfil their biological function.

26 Apr 2022

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

26 Apr 2022

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

21 Apr 2022

Researchers develop a live imaging system to observe collagen synthesis

"Proteins are the building blocks of our body": You have probably heard this phrase before. Proteins are essential to the formation of our body's structures, and their functioning.

21 Apr 2022

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

A new study shows that it is possible to use the genetic sequences of a person's antibodies to predict what pathogens those antibodies will target.

21 Apr 2022

Cell division crucial for the success of macrophage infiltration

Researchers at ISTA discover a crucial process that enables immune cells to get to where they are needed. Study published in Science.

21 Apr 2022

Novel methods for inferring the movement of brain cells during fetal development

The making of a human brain remains a mostly mysterious process that races from an embryonic neural tube to more than 100 billion interconnected neurons in the brain of a newborn. To achieve this marvel of biological engineering, the developing fetal brain must grow, on average, at a rate of roughly 250,000 nerve cells per minute throughout the course of a pregnancy.

21 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons - more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Cell Biology

Tufts scientists discover a previously unknown function performed by astrocytes

Sleep deprivation negatively affects the stem cells in the cornea

Researchers create 3D in vitro model that reveals the origins of human spine

Study shows how DNA changes in Barrett's esophagus cells may predict esophageal cancer

Novel plug-and-play multi-organ chip can be customized to the patient

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Eukaryotes emerged in a no-oxygen environment in the ocean, research suggests

Cellular reprogramming can lead to better liver tissue regeneration in mice

Discovery about human cells’ stress response could deepen the understanding of various cancers

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

UNIGE scientists develop a novel tool to visualize palmitoylation process in living cells

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Researchers develop a live imaging system to observe collagen synthesis

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

Cell division crucial for the success of macrophage infiltration

Novel methods for inferring the movement of brain cells during fetal development

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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