Cell Biology

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Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A-; a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection-;is controlled.

13 Aug 2021

Structure of BRCA2 protein complex critical for DNA repair solved

The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA.

13 Aug 2021

Biomedical scientists need to do more to improve the relevance, reproducibility of cell culture research

There is an urgent need for reporting of biomedical research on mammalian cells to be more standardized and detailed and for greater control and measurement of the environmental conditions of cell cultures.

13 Aug 2021

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells.

13 Aug 2021

Study uncovers a subset of human short introns spliced out by a distinct mechanism

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins.

13 Aug 2021

Researchers identify genetic program in fruit fly that protects neurons from degeneration

Researchers at the University of Bonn have identified a previously unknown genetic program in the fruit fly. The genetic material involved controls the development of the neurons while also protecting them from degeneration.

13 Aug 2021

Researchers develop silica nanostructure for selective synthesis of enantiomers in cells

As COVID-19 vaccinations are well underway, people await a return to normal life. However, fears also grow due to unforeseen side effects like rare thrombosis. In the body, life is maintained by the movement of substances or energy.

13 Aug 2021

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

A team of Massachusetts General Hospital researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.

12 Aug 2021

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities -; and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

12 Aug 2021

Researchers identify human sperm mutations that can cause disease in children

Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or genetic makeup.

12 Aug 2021

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

A team of University of California, Irvine, scientists have discovered a novel pharmacological approach to attenuate the mitochondrial dysfunction that drives diet-induced obesity.

12 Aug 2021

UC San Diego scientists develop new method to keep cultured cells healthy

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

12 Aug 2021

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.

12 Aug 2021

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

A study led by Northwestern Medicine investigators has identified the molecular mechanisms within protein complexes that promote cell-to-cell adhesion and communication, according to findings published in the Proceedings of the National Academy of Sciences.

11 Aug 2021

Cell Biology

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

Structure of BRCA2 protein complex critical for DNA repair solved

Biomedical scientists need to do more to improve the relevance, reproducibility of cell culture research

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Study uncovers a subset of human short introns spliced out by a distinct mechanism

Researchers identify genetic program in fruit fly that protects neurons from degeneration

Researchers develop silica nanostructure for selective synthesis of enantiomers in cells

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

Researchers identify human sperm mutations that can cause disease in children

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

UC San Diego scientists develop new method to keep cultured cells healthy

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

Brain memory signals may influence blood sugar levels, rat study finds

Scientists develop new approach to identify proteins in the living brain

New stem-cell-carrying hydrogel could help the heart recover from myocardial ischemia

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Novel model describes the coordination of beating cilia

HKU research team sheds critical insight on what causes abnormal embryo elongation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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