Cell Biology

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Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue and hair loss.

8 Jun 2022

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Using advanced microscopy techniques, researchers at Karolinska Institutet and Stockholm University in Sweden have visualized in unprecedented detail the machinery that the cells' powerhouses, the mitochondria, use to form their proteins.

8 Jun 2022

Detailed genetic roadmap of glaucoma will help develop new drugs to combat the disease

A new, detailed genetic roadmap of glaucoma – the world's leading cause of irreversible blindness – will help researchers develop new drugs to combat the disease, by identifying potential target areas to stall or reverse vision loss.

8 Jun 2022

Irregularities in production of brain cells may lead to autism spectrum disorder, finds study

Analyzing brain stem cells of patients with autism spectrum disorder (ASD), Rutgers scientists have found evidence of irregularities in very early brain development that may contribute to the neuropsychiatric disorder.

8 Jun 2022

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Axol Bioscience Ltd. (Axol), an established provider of iPSC-derived cells, media, and characterization services for life science discovery, today announced that its human induced pluripotent stem cell (iPSC)-derived ventricular cardiomyocytes have undergone comprehensive in vitro pro-arrhythmia assay (CiPA) validation.

From Axol Bioscience Ltd 8 Jun 2022

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Fasting sends muscle stem cells into a deep resting state that slows muscle repair but also makes them more resistant to stress, according to a Stanford Medicine study of laboratory mice.

7 Jun 2022

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.

7 Jun 2022

Basolateral amygdala may play a larger, overarching role during naturalistic events

The basolateral amygdala (BLA) is a region of the brain that has been almost exclusively studied in the context of fear and emotion.

7 Jun 2022

Phase separation discovery could lead to new interventions to regulate immune activity

Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new study.

6 Jun 2022

Study finds striking epigenetic differences in the airway cells of adult children born to asthmatic mothers

Asthma is a chronic condition that affects 25 million people in the United States. Having a mother with asthma is an important risk factor and a new study may explain why.

6 Jun 2022

MIT researchers identify components of mucus that can inhibit fungal infections

Candida albicans is a yeast that often lives in the human digestive tract and mouth, as well as urinary and reproductive organs.

6 Jun 2022

Persistence of viral RNA following acute infection

Professor Diane Griffin from the Johns Hopkins Bloomberg School of Public Health, USA, has recently explained the persistence mechanism of viral RNA in the human body after clinical recovery from acute infection.

6 Jun 2022

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division.

3 Jun 2022

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

Hospital-acquired infections (HAIs) are often particularly difficult to treat because the pathogens have developed resistance to common antibiotics.

3 Jun 2022

New, efficient protocol to generate microglia from human pluripotent cells for retinal development

This study is led by prof. Jin (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University).

3 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

A new study published in the journal Cell shows that a non-coding RNA molecule regulates mitochondrial gene expression in human cells.

2 Jun 2022

Genetically engineered immune cells target cancer cells that may be responsible for leukemia relapse

Genetically engineered immune cells successfully target the specific cancer cells that may be responsible for relapse of acute myeloid leukemia (AML), a type of blood cancer, and proved effective in animal models of the disease, according to a preclinical study by investigators at Weill Cornell Medicine.

2 Jun 2022

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body's response to central nervous system (CNS) disorders such as Alzheimer's, Huntington's disease and spinal cord injuries.

2 Jun 2022

MD Anderson and National Resilience launch the Cell Therapy Manufacturing Center

The University of Texas MD Anderson Cancer Center and National Resilience, Inc., today announced the launch of a joint venture, the Cell Therapy Manufacturing Center, to accelerate the development and manufacturing of innovative cell therapies for patients with cancer.

2 Jun 2022

Cell Biology

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Detailed genetic roadmap of glaucoma will help develop new drugs to combat the disease

Irregularities in production of brain cells may lead to autism spectrum disorder, finds study

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

Basolateral amygdala may play a larger, overarching role during naturalistic events

Phase separation discovery could lead to new interventions to regulate immune activity

Study finds striking epigenetic differences in the airway cells of adult children born to asthmatic mothers

MIT researchers identify components of mucus that can inhibit fungal infections

Persistence of viral RNA following acute infection

Steady-state DNA motion allows cells to conduct housekeeping tasks under similar nuclear environments

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

New, efficient protocol to generate microglia from human pluripotent cells for retinal development

Brain motor and fear circuits orchestrate the immune response to acute stress

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

Genetically engineered immune cells target cancer cells that may be responsible for leukemia relapse

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

MD Anderson and National Resilience launch the Cell Therapy Manufacturing Center

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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