Cell Biology

RSS

Researchers discover how the sponginess of stem cell nuclei controls cell differentiation

Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they "differentiate" into specialized cells.

3 Jan 2022

New technique combines bioprinting with cryopreservation to construct frozen structures

A new technique takes bioprinting - in which an ink of cells is printed, layer by layer, to form a structure - to a whole new, and icy level. Investigators from the Zhang lab at Brigham and Women's Hospital have developed a technology that they term "cryobioprinting," a method that uses a bioink embedded with cells to print frozen, complex structures that can be easily stored for later use.

31 Dec 2021

New study shows how cells eat the things around them

A new study shows how cell membranes curve to create the "mouths" that allow the cells to consume things that surround them.

31 Dec 2021

Microgravity likely to contribute to life-saving stem cell advances on Earth

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

30 Dec 2021

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19 - knowledge that could help us to reduce the threat to humans of infectious disease - have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

New research suggests convalescent plasma from unvaccinated donors is not effective against the Omicron variant, however, “hybrid” convalescent plasma from donors who recovered from COVID-19 infection and are vaccinated provides considerable antibody protection.

29 Dec 2021

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

Stem cell scientists have revealed the origins of a common ovarian cancer by modeling fallopian tube tissues, allowing them to characterize how a genetic mutation puts women at high risk for this cancer.

29 Dec 2021

New techniques enable visualization of DNA repair machinery in detail

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as cancer.

29 Dec 2021

New optogenetic tool uses focused light to reduce actin and myosin-based contractile force

Cell generated force plays essential roles in a wide range of biological processes, such as cell motility, cytokinesis, and tissue morphogenesis. In a study published in Nature Communications, a research team led by the Division of Quantitative Biology at the National Institute for Basic Biology in Japan has successfully developed "OptoMYPT"：an optogenetic tool that utilizes focused light to reduce actin and myosin-based contractile force.

29 Dec 2021

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Scientists at the La Jolla Institute for Immunology have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.

24 Dec 2021

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.

23 Dec 2021

Researchers unravel how our organs know when to stop growing

The smallest fish in the world, the Paedocypris, measures only 7 millimeters. This is nothing compared to the 9 meters of the whale shark.

23 Dec 2021

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

A little wiggle room might be just what the doctor ordered. New research suggests that the peptides - short chunks of protein - used to treat Type 2 diabetes may be more effective if they're able to flexibly move back and forth between different shapes.

23 Dec 2021

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

23 Dec 2021

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

23 Dec 2021

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.

23 Dec 2021

New study shines light on how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

22 Dec 2021

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

UAB and Vall d'Hebron researchers identified the mechanism by which inhibitors of the ERK5 protein kinase impair the proliferation of cancer cells and induce their death. The results, obtained using human cancer cell lines, demonstrate that ERK5 inhibition activates cytotoxic autophagy, a process that triggers cancer cell death, without affecting healthy cells. A combination of ERK5 inhibitors and chemotherapy could improve cancer treatment.

22 Dec 2021

Researchers use network modeling to hone in on cancer gene interactions critical to malignancy

Wilmot Cancer Institute researchers are a step closer to understanding the complex gene interactions that cause a cell to become malignant.

21 Dec 2021

Polyrotaxane-based biomaterials enhance the connection between epithelial cells

The field of tissue engineering is constantly exploring the possibility of using different properties of various biomaterials to achieve tissue regeneration.

21 Dec 2021

Cell Biology

Researchers discover how the sponginess of stem cell nuclei controls cell differentiation

New technique combines bioprinting with cryopreservation to construct frozen structures

New study shows how cells eat the things around them

Microgravity likely to contribute to life-saving stem cell advances on Earth

Intestinal organoids used to explain why bats infected with viruses do not succumb to diseases

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

New techniques enable visualization of DNA repair machinery in detail

New optogenetic tool uses focused light to reduce actin and myosin-based contractile force

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

Researchers unravel how our organs know when to stop growing

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

New study shines light on how brain cells die in prion diseases

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

Researchers use network modeling to hone in on cancer gene interactions critical to malignancy

Polyrotaxane-based biomaterials enhance the connection between epithelial cells

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Latest Life Science News