Cell Biology

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New method reveals how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

19 Jan 2021

FISH technique can be used to probe sperm DNA for chromosomal defects

Chemotherapy and radiation treatments are known to cause harsh side effects that patients can see or feel throughout their bodies.

19 Jan 2021

Gene-cutting system may play second role as a genetic dimmer switch

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes.

19 Jan 2021

Inflammation may contribute to the persistence of C. diff infection, shows study

A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that enable C. diff to thrive.

19 Jan 2021

Research finds new evidence about the mechanisms controlling skin repair and regeneration

As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal.

19 Jan 2021

Study: Perineuronal nets are responsible for long-term stability of mental maps

A reliable sense of space is essential for daily life and memory formation. Removing sugar-coated proteins around neurons in the brains' internal gps makes the mental map of space unstable, shows in a study published in the journal Nature communications.

19 Jan 2021

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Researchers investigated how cancer genes lead to the breakdown of the capsule that prevents cancerous cells from invading the surrounding healthy tissues and - find a hijacked "molecular crowbar".

18 Jan 2021

Novel organoid models illuminate path to cervical cancers

How do tumors develop in the cervix? Many new details are now known about this question. This is also thanks to Dr. Cindrilla Chumduri from the Biocentre at the University of Würzburg.

18 Jan 2021

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3D arrangements that our bodies can master on their own.

18 Jan 2021

Researchers figure out the precise mechanics involved in cell motility

Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. The findings were published in the journal Proceedings of the National Academy of Sciences.

18 Jan 2021

Timing may be critical when administering treatment after brain injury

Researchers from the National Institutes of Health have discovered Jekyll and Hyde immune cells in the brain that ultimately help with brain repair but early after injury can lead to fatal swelling, suggesting that timing may be critical when administering treatment.

18 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

Study provides a mathematical description of how tumor metastasis starts

A scientific study carried out by the Universidad Carlos III de Madrid and the Universidad Complutense de Madrid (UCM) has produced a mathematical description of the way in which a tumor invades the epithelial cells and automatically quantifies the progression of the tumor and the remaining cell islands after its progression.

18 Jan 2021

Researchers produce first African lion in-vitro embryos after vitrification of immature oocytes

A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) inGermany, Givskud Zoo - Zootopia in Denmark and the University of Milan in Italy succeeded in producing the very first African lionin-vitroembryos after the vitrification of immature oocytes.

18 Jan 2021

Study reveals new way to target cancer’s nutritional needs

Scientists discover a way to target cancer’s nutritional needs, which could lead to a new way to treat the disease, according to a study published in Nature Communications today (Thursday).

18 Jan 2021

Newly-identified nutrient helps the gut recall prior infections and kill invading bacteria

Scientists studying the body's natural defenses against bacterial infection have identified a nutrient--taurine--that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn).

16 Jan 2021

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways.

16 Jan 2021

Researchers discover unexpected role for the clock gene in prostate cancer progression

Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It's no wonder then that disrupting the clock can wreak havoc on our body.

15 Jan 2021

Computational method uses heat map data to reverse engineer 3D chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Highly sensitive technique helps measure the extent of cytoskeleton bundling

A research group from Kumamoto University, Japan has developed a highly sensitive technique to quantitatively evaluate the extent of cytoskeleton bundling from microscopic images. Until now, analysis of cytoskeleton organization was generally made by manually checking microscopic images.

14 Jan 2021

Cell Biology

New method reveals how pharmaceuticals induce cancer cell death

FISH technique can be used to probe sperm DNA for chromosomal defects

Gene-cutting system may play second role as a genetic dimmer switch

Inflammation may contribute to the persistence of C. diff infection, shows study

Research finds new evidence about the mechanisms controlling skin repair and regeneration

Study: Perineuronal nets are responsible for long-term stability of mental maps

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Novel organoid models illuminate path to cervical cancers

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Researchers figure out the precise mechanics involved in cell motility

Timing may be critical when administering treatment after brain injury

New computational technique accurately differentiates between data from tumor cells and normal cells

Study provides a mathematical description of how tumor metastasis starts

Researchers produce first African lion in-vitro embryos after vitrification of immature oocytes

Study reveals new way to target cancer’s nutritional needs

Newly-identified nutrient helps the gut recall prior infections and kill invading bacteria

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Researchers discover unexpected role for the clock gene in prostate cancer progression

Computational method uses heat map data to reverse engineer 3D chromosome models

Highly sensitive technique helps measure the extent of cytoskeleton bundling

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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