Cell Biology

RSS

New analytical method visualizes cell functions in vasculature-on-a-chip

A microphysiological system (MPS), also known as an organ-on-a-chip, is a 3D organ construct using human cells that help reveal how organs respond to drugs and environmental stimuli.

20 Aug 2021

Researchers identify key protein that plays an essential role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

20 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Researchers use ancient mammalian proteins to develop mRNA delivery system

Using a family of mammalian proteins adopted from ancient retroviral legacy genes, researchers have developed a novel system for programmable intracellular mRNA delivery.

20 Aug 2021

Npas4 gene may be a master timekeeper for the brain's circadian clock

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research led by UT Southwestern scientists suggests.

20 Aug 2021

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Investigators who previously developed a recipe for turning skin cells into primitive muscle-like cells that can be maintained indefinitely in the lab without losing the potential to become mature muscle have now uncovered how this recipe works and what molecular changes it triggers within cells.

19 Aug 2021

Scientists develop a new way to deliver molecular therapies to cells

Researchers from MIT, the McGovern Institute for Brain Research at MIT, the Howard Hughes Medical Institute, and the Broad Institute of MIT and Harvard have developed a new way to deliver molecular therapies to cells.

19 Aug 2021

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

Researchers identify antibodies that could protect against alphaviruses

Alphaviruses - mosquito-borne viruses that can trigger brain infections and arthritis - may have met their match.

19 Aug 2021

Arteriolar niche used by breast cancer cells to prepare for metastasis

More than 43,000 American women will die from breast cancer this year. Most of those deaths will occur after the cancer has spread to other organs, a process called metastasis. This involves at least five major steps.

19 Aug 2021

Memory of specific events does not deteriorate with age in cuttlefish

Cuttlefish can remember what, where, and when specific events happened - right up to their last few days of life, researchers have found.

18 Aug 2021

Auditory and speech processing occur in parallel in the brain

After years of research, neuroscientists have discovered a new pathway in the human brain that processes the sounds of language.

18 Aug 2021

Remote controlling of CAR-T cells with heat to precisely target tumors

A team of researchers led by bioengineers at the Georgia Institute of Technology is expanding the precision and ability of a revolutionary immunotherapy that is already transforming oncology. CAR T-Cell therapy has been hailed by patients, clinical-researchers, investors, and the media as a viable cure for some cancers.

18 Aug 2021

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

A new phase I clinical study shows, for the first time, how treatment with a type of stem cell called mesenchymal stromal cells is able to regulate important factors driving inflammation in patients with chronic obstructive pulmonary disease (COPD) for a period for time.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Recent research has found that changes in the gut microbiota - the trillions of bacteria and other microbes that live in the intestines - can alter the brain and behavior. Now, a study led by scientists at UCLA could elucidate how and why that phenomenon occurs.

17 Aug 2021

Age and sex affect the outcomes of time-restricted eating

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.

17 Aug 2021

Cell Biology

New analytical method visualizes cell functions in vasculature-on-a-chip

Researchers identify key protein that plays an essential role in male fertility

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Researchers use ancient mammalian proteins to develop mRNA delivery system

Npas4 gene may be a master timekeeper for the brain's circadian clock

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Scientists develop a new way to deliver molecular therapies to cells

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

Researchers identify antibodies that could protect against alphaviruses

Arteriolar niche used by breast cancer cells to prepare for metastasis

Memory of specific events does not deteriorate with age in cuttlefish

Auditory and speech processing occur in parallel in the brain

Remote controlling of CAR-T cells with heat to precisely target tumors

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

New assay using fresh uncultured lung tumor cells could guide personalized treatments

New bioengineered lung model could help scientists to advance research in lung conditions

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Age and sex affect the outcomes of time-restricted eating

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Latest Life Science News