Cell Biology

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Researchers discover working mechanism of potential drug targets for COVID-19

A team of international researchers, including McGill Professor Stéphane Laporte, have discovered the working mechanism of potential drug targets for various diseases such as cancer, rheumatoid arthritis, and even COVID-19.

28 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

The Lundquist Institute announced that it has received a generous $5 million, 5-year grant from the California Institute for Regenerative Medicine that will allow its PhD students, postdoctoral fellows and clinical fellows to pursue careers in stem cell biology and regenerative medicine.

24 Sep 2021

New 3D pancreatic cancer model could be used to develop and test targeted treatments

An international team of scientists have created a three-dimensional (3D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test targeted treatments.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Bubble and droplet formation theory inspires a framework for engineering living cells

The heady math that describes how bubbles form in a glass of Champagne has inspired a framework for engineering living cells.

23 Sep 2021

Immune cells in the brain join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Adhesive protein facilitates cluster formation in circulating tumor cells

Circulating tumor cells (CTCs) with stem cell features use the adhesive protein ICAM1 to facilitate formation of CTC clusters, which can travel from primary tumors to other organs in the body, according to a Northwestern Medicine study published in Nature Communications.

22 Sep 2021

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

Cell Biology

Researchers discover working mechanism of potential drug targets for COVID-19

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

New 3D pancreatic cancer model could be used to develop and test targeted treatments

Study identifies master regulator behind the development of antibody-producing cells

Researchers discover how Rift Valley fever virus enters cells

New discovery offers clues to overcoming resistance to cancer therapies

Study provides novel insights into how KLF4 influences gene expression

Bubble and droplet formation theory inspires a framework for engineering living cells

Immune cells in the brain join together to break down toxic proteins more quickly

Adhesive protein facilitates cluster formation in circulating tumor cells

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Researchers seek to identify the role of hypoxia on red blood cell aging

Study paves the way for development of novel delivery systems to suppress HIV

Researchers provide structural insights into HCV receptor binding and entry

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Careful pipetting reduces the stress on cells in culture

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

Differences in DNA methylation could accurately predict progression of liver disease

Researchers develop new method to track the development of cancer cells

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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