Cell Biology

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Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Within the brain and other parts of the nervous system, synapses are key junctional points in between neurons (the nerve cells) where critical signals are transmitted. More specifically, the "glutamatergic" synapses are the prime "excitatory" synapse junctions that neurons use to activate each other and are known to have broad diversity in size and shape.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

New research is advancing understanding of certain cancers and complex congenital disorders by illuminating how BRD4, a protein that scientists have studied for years, directs the spatial organization of DNA within the nucleus of the cell, a function critical for stem cell differentiation into muscle cells.

7 Oct 2021

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

Specialized cells that conduct electricity to keep the heart beating have a previously unrecognized ability to regenerate in the days after birth, a new study in mice by UT Southwestern researchers suggests.

7 Oct 2021

Scientists make inroads into creating an atlas of the mouse brain

It takes billions of cells to make a human brain, and scientists have long struggled to map this complex network of neurons.

6 Oct 2021

Neuroscientists unveil detailed atlas of brain cells

When you clicked to read this story, a band of cells across the top of your brain sent signals down your spine and out to your hand to tell the muscles in your index finger to press down with just the right amount of pressure to activate your mouse or track pad.

6 Oct 2021

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Open any introductory biology textbook, and you'll see a familiar diagram: A blobby-looking cell filled with brightly colored structures – the inner machinery that makes the cell tick.

6 Oct 2021

Toxic fatty acids trigger cell death in damaged neurons

Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows.

6 Oct 2021

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

The NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

6 Oct 2021

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

A team in the College of Medicine led by Drs. Juan Ianowski (PhD) and Julian Tam (MD) found that sodium transport is abnormal in lungs with CF.

6 Oct 2021

Novel technique enables 3D visualization of cells containing melanin pigment

To understand the biological underpinnings of skin and hair pigmentation and related diseases such as albinism or melanoma, scientists and doctors need quantitative, three-dimensional information about the architecture, content and location of pigment cells. Penn State College of Medicine researchers have developed a new technique that allows scientists to visualize every cell containing melanin pigment in 3D, in whole zebrafish.

6 Oct 2021

Researchers develop new method to predict biomaterial's capacity to induce tissue regeneration

Researchers from the Polymer and Advanced Materials Group at the Universitat Jaume I in Castellón have developed an in vitro method to predict the capacity of a biomaterial to induce bone and soft tissue regeneration.

5 Oct 2021

New mathematical tool used to study the genetic interactions associated with cancer

Biologists at Cold Spring Harbor Laboratory are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems.

5 Oct 2021

CAR-T cells require an abundance of antigens to efficiently kill solid tumors

Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer.

5 Oct 2021

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

Aging-US published "Cellular senescence in lymphoid organs and immunosenescence" which reported that immunosenescence is a multi-faceted phenomenon at the root of age-associated immune dysfunction.

5 Oct 2021

Fully vaccinated people with prior SARS-CoV-2 infection have more memory B cells, study shows

A new study by University of Minnesota Medical School researchers is revealing that some people who received an mRNA vaccination for COVID-19 have greater immune responses compared to others.

4 Oct 2021

Study sheds new light on the mechanisms required for development of adult-born neurons

A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus, according to a Northwestern Medicine study published in Cell Reports.

4 Oct 2021

Glycerin helps calm the red itchy patches in psoriasis model

Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis and now scientists have objective evidence to support their reports.

4 Oct 2021

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases.

4 Oct 2021

Aging produces significant changes in the gut microbiome

Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The findings have been published in the journal Cell Reports.

3 Oct 2021

Cell Biology

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Mouse brain atlas may help understand the complex circuits of the human brain

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

Scientists make inroads into creating an atlas of the mouse brain

Neuroscientists unveil detailed atlas of brain cells

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Toxic fatty acids trigger cell death in damaged neurons

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

Novel technique enables 3D visualization of cells containing melanin pigment

Researchers develop new method to predict biomaterial's capacity to induce tissue regeneration

New mathematical tool used to study the genetic interactions associated with cancer

CAR-T cells require an abundance of antigens to efficiently kill solid tumors

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

Fully vaccinated people with prior SARS-CoV-2 infection have more memory B cells, study shows

Study sheds new light on the mechanisms required for development of adult-born neurons

Glycerin helps calm the red itchy patches in psoriasis model

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

Aging produces significant changes in the gut microbiome

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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