Cell Biology

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New computational model provides clearer picture of shape-changing cells' structure and mechanics

A new computational model developed by researchers from The City College of New York and Yale gives a clearer picture of the structure and mechanics of soft, shape-changing cells that could provide a better understanding of cancerous tumor growth, wound healing, and embryonic development.

11 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

Specific class of biomarkers can accurately indicate the severity of cancer

A cancer diagnosis tells you that you have cancer, but how that cancer will progress is a terrifying uncertainty for most patients. Researchers at Cold Spring Harbor Laboratory have now identified a specific class of biomarkers that can tell a lot about how aggressive a patient's cancer will be.

11 Dec 2018

Research pinpoints two proteins involved in creation of stem cells

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

11 Dec 2018

New computer model predicts prostate cancer progression

An international team of cancer researchers from Denmark and Germany have used cancer patient data to develop a computer model that can predict the course of disease for prostate cancer.

11 Dec 2018

Advanced illumination expands capabilities of light-sheet microscopy

Bruker announces the launch of the Luxendo InVi SPIM AIM next-generation lattice light-sheet microscope, with an advanced illumination module (AIM).

From Bruker Nano Surfaces and Metrology 11 Dec 2018

Scientists use water molecules to track electrical activity of nerve cells

Researchers have discovered a new way to monitor electrical activity in nerve cells; by observing water molecules surrounding neuronal membranes.

11 Dec 2018

Sacrificial immune cells alert body to infection

Scientists have discovered a new mechanism by which immune cells burst to alert the body to infection with Yersinia pestis.

11 Dec 2018

Researchers develop new system for efficiently producing human norovirus

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells to develop into a type of cell that usually lines the intestine, they created a cellular environment that can be used for producing the virus, studying how it interacts with human cells, and investigating potential vaccines.

11 Dec 2018

Study provides new information regarding microRNA function in cellular homeostasis of zebrafish

Cellular pathways represent the intricate metabolic connections between the plethora of signaling pathways, and energetic-sensors in organs.

11 Dec 2018

New study reveals yin-yang personality of dopamine

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which leads to addiction.

11 Dec 2018

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers from the Spanish Research Council at the Centre for Research in Agricultural Genomics and the Institute for Plant Molecular and Cellular Biology, in collaboration with the IATA, have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in plants.

10 Dec 2018

Researchers report novel findings on plant hormone

Jasmonic acid is not just the aromatic odor of the plant Jasminum grandiflorum used in cosmetics and perfume industries. Plants wounded by e.g. chewing herbivores produce jasmonic acid as a defense signal, as a phytohormone to mount their defense responses - this includes for example the formation of toxic substances.

10 Dec 2018

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Proteins are polymers of amino acids that are linked by peptide bonds and they are one of the major classes of bio-molecules existing in a living organism. Proteins are involved in various cellular functions and events like cell signaling, cell adhesion, metabolic reactions, in the generation of immune response and many more.

10 Dec 2018

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

The placenta offers an abundant source of placenta-derived mesenchymal stem cells (pMSCs), which a new study has shown can readily form cell sheets that could be implanted in children with congenital heart defects and offer benefits for heart repair and regeneration compared to commonly used synthetic material-based scaffolds. Congenital heart disease is the leading cause of birth-defect-related illness and death.

9 Dec 2018

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

For the first time, a research team at Lund University in Sweden has successfully reprogrammed mouse and human skin cells into immune cells called dendritic cells.

9 Dec 2018

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Today, the Chan Zuckerberg Initiative announced funding for open-source software efforts to improve image analysis and visualization in biomedicine. Microscopy -- critical to modern cell biology -- generates large volumes of complex data that pose significant challenges for analysis and visualization.

7 Dec 2018

Study sheds new light on microtubule binding proteins and microtubule dynamics

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections.

6 Dec 2018

Researchers identify new type of T cell that could play role in cancer, other diseases

Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute for Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to recognize phospholipids, the molecules that help form cells' outer membranes.

6 Dec 2018

Cell Biology

New computational model provides clearer picture of shape-changing cells' structure and mechanics

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

Specific class of biomarkers can accurately indicate the severity of cancer

Research pinpoints two proteins involved in creation of stem cells

New computer model predicts prostate cancer progression

Advanced illumination expands capabilities of light-sheet microscopy

Scientists use water molecules to track electrical activity of nerve cells

Sacrificial immune cells alert body to infection

Researchers develop new system for efficiently producing human norovirus

Study provides new information regarding microRNA function in cellular homeostasis of zebrafish

New study reveals yin-yang personality of dopamine

Researchers shed new light on how to combat Shiga and ricin toxins

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers report novel findings on plant hormone

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Study sheds new light on microtubule binding proteins and microtubule dynamics

Researchers identify new type of T cell that could play role in cancer, other diseases

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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