Cell Biology

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Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy--causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a microfluidics-based chip for the manipulation and subsequent nucleic-acid analysis of individual cells.

17 Aug 2018

Study: Sperm morphology differs depending on qualities of male bird

In a study published in Behavioral Ecology researchers from Uppsala University show that the same type of sperm is not always the best for all male birds.

17 Aug 2018

Brief exposures to stressors can be beneficial to cells, shows study

We've all heard the expression: "what doesn't kill you makes you stronger." Now, research led by a Salk Institute scientist suggests why, at a cellular level, this might be true.

17 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

Scientists uncover key control mechanism of DNA replication

Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.

16 Aug 2018

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this.

16 Aug 2018

Researchers develop novel statistical method to evaluate gene-to-gene interactions linked with cancer

Research led by Hui-Yi Lin, PhD, Associate Professor of Biostatistics at LSU Health New Orleans School of Public Health, has developed another novel statistical method for evaluating gene-to-gene interactions associated with cancer and other complex diseases.

15 Aug 2018

Study reveals role of RUNX proteins in DNA repair

A study by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia pathway.

15 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Cruciferous vegetables found to protect against colon cancer in mice

Researchers have revealed how vegetables such as broccoli, cabbage and kale help to maintain a healthy gut and protect against colon cancer.

15 Aug 2018

Porvair Sciences' new automation-friendly BactiGrowth plates

Porvair Sciences has extended its BactiGrowth range of specially packaged plates designed to enable high yield growth of bacteria, yeast, mammalian or insect cell lines.

From Porvair Sciences Limited 15 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

Real-time dynamic monitoring of cell's nucleus for effective cancer screening

To test for malignancy or monitor the effectiveness of cancer treatment, a person's tissue must be extracted, sent to a lab, stained and analyzed by a pathologist--a process that can take days to complete and is subject to human error.

15 Aug 2018

Scientists reveal role of 'junk DNA' in cancer dissemination

The more scientists explore so-called "junk" DNA, the less the label seems to fit.

14 Aug 2018

'Zombie' gene protects elephants from cancer, study finds

An estimated 17 percent of humans worldwide die from cancer, but less than five percent of captive elephants - who also live for about 70 years, and have about 100 times as many potentially cancerous cells as humans - die from the disease.

14 Aug 2018

Scientists identify mutational signatures in ovarian cancer

Scientists have identified distinct patterns of genetic mutation among patients with ovarian cancer that could help them personalise treatment in the future.

14 Aug 2018

Researchers design new way to grow nose cells for treating spinal cord injuries

Researchers have designed a new way to grow nose cells in the lab heralding hope for sufferers of spinal cord injuries, including those who are wheelchair bound.

14 Aug 2018

Brown University researchers reveal key physical properties of 'giant' cancer cells

Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse.

14 Aug 2018

Neural stem cells are the key to tail regeneration

Cut off a salamander's tail and, in a few weeks, a near-perfect replacement grows. Do the same to a lizard and a new tail will regrow, but it won't be the same as the original. By comparing tail regeneration between the two animals, researchers at the University of Pittsburgh School of Medicine found that stem cells in the spinal cord are the ultimate limiting factor.

14 Aug 2018