Cell Biology

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Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

Researchers use gene editing to reduce autism symptoms in mice

Researchers have used CRISPR-Cas9 gene editing to treat symptoms of autism in mice. It is hoped that the tool could one day be used to help humans.

25 Jun 2018

Study: Inner nuclear envelope plays role in lipid metabolism

The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings - so-called nuclear pores.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

Distek, Inc. launches revolutionary benchtop scale bioreactor

Distek, Inc. has revolutionized benchtop scale bioreactors with the release of our BIOne 1250 bioprocess control station for both mammalian and microbial models.

22 Jun 2018

Study provides clues to how cancer cells develop resistance to chemotherapies

About half of all drugs, ranging from morphine to penicillin, come from compounds that are from - or have been derived from - nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.

22 Jun 2018

Study reveals how mTORC1-driven changes in crowding could influence major diseases

Among the most studied protein machines in history, mTORC1 has long been known to sense whether a cell has enough energy to build the proteins it needs to multiply as part of growth.

22 Jun 2018

Scientists identify gene that triggers senescence

Scientists seeking to unlock the secrets of cellular aging have identified a gene that triggers senescence, a phenomenon in which cells stop dividing.

22 Jun 2018

Researchers discover new type of cell that hinders formation of fat cells

Obesity is the plague of our times. Some 80 percent of obese people will develop Type 2 diabetes at some point in their lives, and being overweight is also a significant risk factor for cancer and heart attacks.

22 Jun 2018

Lipid-scrambling DNA enzyme outperforms naturally occurring counterpart, say researchers

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells.

22 Jun 2018

Study reveals new target to halt tumor growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes - tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.

21 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

USC study reveals how the cell launches emergency response to repair damaged DNA

The cell has its own paramedic team and emergency room to aid and repair damaged DNA, a new USC Dornsife study reveals.

21 Jun 2018

Researchers develop reliable DNA barcodes for biomedical research

Researchers have developed a new way of correcting the errors previously seen in DNA barcodes, yielding more reliable results for biomedical research.

21 Jun 2018

Study: Oxidative stress can be used against tumors to treat cancer

Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.

21 Jun 2018

$Study shows fat cells increase in size and number upon exposure to fracking chemicals$