Cell Biology

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Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Salk researchers discover molecule that destroys key HIV protein

One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously.

1 Jun 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer - resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

31 May 2018

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

A study conducted at the Massachusetts Institute of Technology has identified why the ApoE4 gene increases the risk of developing Alzheimer's disease, and why the ApoE3 gene reduces the risk.

31 May 2018

Weight gain may be the result of inefficient fat metabolism

Researchers from the Karolinska Institutet have shown that protracted weight gain can, in some cases, be attributed to a reduced ability to metabolise fat.

31 May 2018

Study shows blood stem cells compensate for immune cell deficiencies

Researchers have shown that if certain blood stem cells that produce immune cells are deficient, other blood stem cells compensate by overproducing the immune cells that are lacking.

30 May 2018

Researchers uncover the cause of rheumatoid arthritis

A team of researchers have identified the cellular network involved in initiating and maintaining chronic inflammation in rheumatoid arthritis.

30 May 2018

Small defect in tissues can lead normal cells to take on characteristics of diseased cells

Homeowners know that one little termite can lead to big problems: while termites are efficient at gnawing away at wood, they can do even more damage if the wood is already broken or has another defect.

29 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

Genomic medicine may one day revolutionize cardiovascular care

The American Heart Association has summarized the state-of-the science in the field of genomic medicine for studying cardiovascular traits and disorders, therapeutic screening.

29 May 2018

Miniaturized device offers new way to gain insight into cell processes and communication

Like humans, cells of the same species each have a distinct "personality." When confronted with an external stimulus like a virus, they each secrete a different quantity of molecules and communicate with each other to a varying degree.

28 May 2018

Study identifies neurons involved in control of aggression

Researchers from the Karolinska Insitutet in Sweden have made a new discovery about the biological mechanism underlying aggressive behavior.

28 May 2018

Researchers call for new genetic tests for congenital diseases

Researchers have discovered that genetic mutations called epivariations are the cause of certain neurodevelopmental disorders and congenital diseases.

25 May 2018

Study establishes the importance of haploid cells

A new study has found that when the cell replication process exceeds or has less than a pair of chromosome set (a genome), destabilization occurs.

25 May 2018

New research will use mathematics to solve mysteries in cell biology

A new interdisciplinary research and education center at the University of California, Irvine will apply the power of mathematics to some of the more vexing mysteries in cell biology.

25 May 2018

Researchers reveal stimulatory effects of myelin on young neural cells

Recovery after severe spinal cord injury is notoriously fraught, with permanent paralysis often the result. In recent years, researchers have increasingly turned to stem cell-based therapies as a potential method for repairing and replacing damaged nerve cells.

24 May 2018

Scientists uncover the cause of insulin resistance in obesity

A team of international researchers has identified a pathway by which obesity results in reduced insulin sensitivity.

24 May 2018

Study links cell size with commitment to division

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow large enough to produce four key proteins in adequate amounts.

24 May 2018

Scientists create small, self-contained spaces inside mammalian cells

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

23 May 2018