Cell Biology

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Researchers solve protein puzzle that paves way for new cancer therapies

Researchers at Oregon State University have solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies.

13 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

UZH scientists identify enzyme that controls cell division

When a cell divides, its constituents are usually evenly distributed among the daughter cells. UZH researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Researchers discover why CRISPR gene editing sometimes fails

A study has explained for the first time why the CRISPR gene editing tool fails to work in 15% cases, and has suggested methods to prevent this.

11 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

Alternative splicing plays vital role in adult muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

11 Jul 2018

Cellular 'garbage disposal' may actually work on some of the proteins to neuronal development

Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.

11 Jul 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Study reveals how M. tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens.

10 Jul 2018

Stem cell study brings scientists closer to understanding schistosomiasis

Scientists have made an important discovery that could lead to the development of new treatments for schistosomiasis, a common parasitic disease.

10 Jul 2018

Researchers discover mechanism that shuts down cell-to-cell communications pathway

Cellular functions rely on several communications networks that allow cells to rapidly respond to signals affecting the organism.

10 Jul 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

Researchers identify genes associated with aggressive behavior

Researchers from the University of Barcelona and collaborators have pin-pointed forty genes that are associated with aggressive behaviors in humans and in mice.

9 Jul 2018

Bacteria-powered solar cell can produce energy even when skies are overcast

Researchers have developed a sustainable biogenic solar cell, which uses bacteria to convert light into energy and has generated the strongest current ever.

9 Jul 2018

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Protein complex that helps shape destiny of developing T cells identified

Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, St. Jude Children's Research Hospital scientists have reported.

9 Jul 2018

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.

9 Jul 2018

Single-cell RNA sequencing reveals how complex brain circuit works

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

6 Jul 2018

Researchers find new way to convert skin cells into pluripotent stem cells

Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted to cells typical of early embryos, so-called induced pluripotent stem cells.

6 Jul 2018