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Eosinophils contribute to antiviral host defense mechanisms during influenza

Eosinophils residing in the airways of mice respond to influenza A virus infection through alterations in surface expression of various markers necessary for migration and cellular immunity responses, according to research published in the Journal of Leukocyte Biology by researchers from Le Bonheur Children's Hospital and the University of Tennessee Health Science Center.

5 Aug 2020

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

A recent research endeavor from the UK, currently available on the medRxiv preprint server, indicates that spike 614G variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) increases in frequency relative to 614D variant in a selective advantage manner – but without higher coronavirus disease (COVID-19) mortality rates.

5 Aug 2020

A SARS-CoV-2 assay using plant proteins

Researchers in South Africa have developed a serological assay that readily detects antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using recombinant viral proteins produced in plants.

5 Aug 2020

Warming climate in Southern California may increase risk of West Nile outbreaks

As climate change brings hotter weather to Southern California, coastal populations from San Diego to Santa Barbara may face an increased risk of contracting West Nile virus and other mosquito-borne diseases, suggests a new study led by researchers at the University of California, Berkeley.

5 Aug 2020

NIH-Moderna investigational vaccine protects mice from infection with SARS-CoV-2

The investigational vaccine known as mRNA-1273 protected mice from infection with SARS-CoV-2, the virus that causes COVID-19, according to research published today in Nature.

5 Aug 2020

Evidence for antibody longevity in COVID-19 patients

A study led by researchers at the University of Toronto, Canada, has found evidence that immunoglobulin G (IgG) antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are sustained for at least three months.

5 Aug 2020

New serological test for COVID-19 helps determine herd immunity, vaccine efficacy

New COVID-19 test evaluates herd immunity and vaccine efficacy with high accuracy.

5 Aug 2020

Existing drug used to treat alcoholism is potentially effective against COVID-19

A team of chemists from HSE University and the Zelinsky Institute of Organic Chemistry used molecular modelling to find out that two medications that have been known for a long time can be used to fight SARS-CoV-2.

5 Aug 2020

NIH harnesses artificial intelligence and medical imaging to fight COVID-19

The National Institutes of Health has launched the Medical Imaging and Data Resource Center, an ambitious effort that will harness the powers of artificial intelligence, and medical imaging to fight COVID-19.

5 Aug 2020

European Commission approves first drug for hepatitis D

What started off as basic research 25 years ago has now lead to a successfully approved drug: The entry blocker bulevirtide (brand name Hepcludex, formerly known as Myrcludex B), jointly developed by researchers from Heidelberg University Hospital (UKHD) and the Medical Faculty of Heidelberg, the DZIF and other partners, has now been approved by the European Commission.

5 Aug 2020

Epidemic model demonstrates potential risks COVID-19 could pose for firefighting community

With wildfire season in full swing, a COVID-19 outbreak at a traditional large fire camp is a potential disaster.

5 Aug 2020

New UK supply contract for COVID-19 sample collection kits

EKF Diagnostics Holdings plc, the AIM listed point-of-care business, announces that it has received an initial order worth £3 m from a partner from the private sector to supply PrimeStore MTM, a novel patented sample collection device, to be used in a COVID-19 testing programme for UK staff.

From EKF Diagnostics 5 Aug 2020

Launching a rapid test for COVID-19

Professor Zhanfeng Cui from the University of Oxford speaks to News-Medical about his research into COVID-19, and how he developed a rapid COVID-19 test.

5 Aug 2020

Study shows higher COVID-19 rates among minority and socioeconomically disadvantaged children

Minority and socioeconomically disadvantaged children have significantly higher rates of COVID-19 infection, a new study led by Children's National Hospital researchers shows.

5 Aug 2020

Could labs that test livestock ease covid testing backlog for people? Well … maybe.

In a heated exchange late last month on CNN's State of the Union, host Jake Tapper pressed Adm. Brett Giroir, the Health and Human Services assistant secretary who oversees COVID testing efforts for the Trump administration, on why the government isn't requiring commercial labs to increase testing capacity in order to speed turnaround time.

5 Aug 2020

Laboratory test shows only 60% of COVID-19 patients develop protective antibodies

A laboratory test that has now been developed by a study group from MedUni Vienna is able to determine whether COVID-19 patients develop protective antibodies after having the disease.

5 Aug 2020

Pandemic’s bumps and backlash shape Montana race poised to steer US Senate

Bradshaw Sumners watched throughout February as COVID-19 hot spots developed in major American cities, waiting to see when the coronavirus pandemic would manifest in Montana.

5 Aug 2020

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

In a new study published on the preprint server bioRxiv researchers characterized the crystal structure of the antibody-SARS-CoV-2 RBD complex in an attempt to find the epitope and the mechanism that enables cross-neutralization.

5 Aug 2020

Large proportion of UK healthcare workers may have already had Covid-19 infection

A large proportion of UK healthcare workers may already have been infected with Covid-19, according to new research led by the University of East Anglia in collaboration with University College London.

5 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Disease/Infection News

Eosinophils contribute to antiviral host defense mechanisms during influenza

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

A SARS-CoV-2 assay using plant proteins

Warming climate in Southern California may increase risk of West Nile outbreaks

NIH-Moderna investigational vaccine protects mice from infection with SARS-CoV-2

Evidence for antibody longevity in COVID-19 patients

New serological test for COVID-19 helps determine herd immunity, vaccine efficacy

Existing drug used to treat alcoholism is potentially effective against COVID-19

NIH harnesses artificial intelligence and medical imaging to fight COVID-19

European Commission approves first drug for hepatitis D

Epidemic model demonstrates potential risks COVID-19 could pose for firefighting community

New UK supply contract for COVID-19 sample collection kits

Launching a rapid test for COVID-19

Study shows higher COVID-19 rates among minority and socioeconomically disadvantaged children

Could labs that test livestock ease covid testing backlog for people? Well … maybe.

Laboratory test shows only 60% of COVID-19 patients develop protective antibodies

Pandemic’s bumps and backlash shape Montana race poised to steer US Senate

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

Large proportion of UK healthcare workers may have already had Covid-19 infection

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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