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New ground-breaking initiative aims to find new treatments for leishmaniasis and Chagas disease

The Drugs for Neglected Diseases initiative and four pharmaceutical firms, Eisai Co Ltd, Shionogi & Co Ltd, Takeda Pharmaceutical Ltd, and AstraZeneca plc have announced the start of a ground-breaking initiative to accelerate and cut the cost of early stage drug discovery for two of the world’s most neglected diseases, leishmaniasis and Chagas disease.

30 May 2015

Scientists study active substance against dreaded hospital pathogen Staphylococcus aureus

In the German Center for Infection Research (DZIF), scientists from the universities of Tübingen, Münster and Munich join forces and prepare together with the company Hyglos clinical studies on an active substance against the dreaded hospital pathogen Staphylococcus aureus: A highly effective protein from bacteria-specific viruses, so-called bacteriophages, shall rapidly kill the bacteria, which frequently occur in the nose.

30 May 2015

Pennsylvania confirms first 2015 detections of West Nile Virus from mosquito sample

The Pennsylvania Departments of Environmental Protection and Health are reporting the confirmation of the first 2015 detections of West Nile Virus from a mosquito sample that was collected on May 22 in Springettsbury Township, York County and a bird found May 26 in Harris Township, Centre County.

30 May 2015

First European approval of drug to treat genetic kidney disease ADPKD

Otsuka Pharmaceutical Co., Ltd. announced that the European Commission has granted marketing authorisation for JINARC® (tolvaptan) for the treatment of ADPKD in adults who have chronic kidney disease (CKD) stage one to three at initiation of treatment with evidence of rapidly progressing disease

29 May 2015

For World No-Tobacco Day WHO makes a stand against illicit tobacco trade

May 31 2015 is World No Tobacco Day and the World Health Organization (WHO) is using this opportunity to bring attention to the illicit trade in tobacco and try to bring an end to it by urging Member States to sign the Protocol to Eliminate the Illicit Trade in Tobacco Products...

29 May 2015

New TB-Profiler tool to find appropriate drugs for TB patients may improve likelihood of cure

Finding out what drugs can be used to treat a patient with tuberculosis (TB) can be sped up by days or weeks, thanks to a new free online tool. The new TB-Profiler tool, developed by a team of scientists led by Dr Taane Clark at the London School of Hygiene & Tropical Medicine, analyses and interprets genome sequence data to predict resistance to 11 drugs used for the treatment of TB.

29 May 2015

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Duke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).

29 May 2015

Researchers find weak spot in some antibiotic-resistant bacteria

Using a complex modeling program that helps analyze the physical dynamics of large, structurally complex protein molecules, a research team has made progress towards finding a weak spot in the architecture of a group of enzymes that are essential to antibiotic resistance in a number of bacteria.

29 May 2015

Healthcare workers serve as vector for MRSA transmission in nursing home settings

Healthcare workers frequently contaminate their gloves and gowns during every day care of nursing homes residents with drug resistant Staphylococcus aureus or MRSA, according to a new study. The findings were published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

29 May 2015

Clinical trial suggests HIV patients should start therapy sooner rather than later

Findings from a large-scale clinical trial have shown that people with HIV should start antiretroviral therapy as soon as they have been diagnosed, irrespective of what their CD4+ count is...

28 May 2015

Research findings could help guide development of potential treatments for HCV

Warring armies use a variety of tactics as they struggle to gain the upper hand. Among their tricks is to attack with a decoy force that occupies the defenders while an unseen force launches a separate attack that the defenders fail to notice.

28 May 2015

Earlier antiretroviral treatment benefits HIV-infected individuals

A major international randomized clinical trial has found that HIV-infected individuals have a considerably lower risk of developing AIDS or other serious illnesses if they start taking antiretroviral drugs sooner, when their CD4+ T-cell count--a key measure of immune system health--is higher, instead of waiting until the CD4+ cell count drops to lower levels. Together with data from previous studies showing that antiretroviral treatment reduced the risk of HIV transmission to uninfected sexual partners, these findings support offering treatment to everyone with HIV.

28 May 2015

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Actavis plc, a leading global specialty pharmaceutical company committed to infectious disease treatment innovation, today announced the creation of SHARE ID (Sharing Hospital data to Advance Research and Enhance patient care in Infectious Diseases), a collaborative program to leverage real-world data to advance the delivery and effectiveness of care for patients with serious infections due to antibiotic-resistant pathogens.

27 May 2015

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

Borrelidin is a naturally occurring antibiotic isolated from the Streptomyces species and initially from Streptomyces rochei in 1949. It is called Borrelidin because it was firstly discovered as having anti-Borrelia activity. Borrelia is a type of bacteria...

27 May 2015

New tool could help identify pathogens in food and beverages

Researchers at the National Polytechnic Institute (IPN) in Mexico, developed a technology capable of identifying pathogens in food and beverages. This technique could work in the restaurant industry as a biosensor to detect in what conditions food is before being eaten in order to avoid possible gastrointestinal diseases.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

AbbVie presented new results from the Phase 3 GIFT-I study of its investigational, all-oral, interferon (IFN)- and ribavirin (RBV)-free, two direct-acting antiviral treatment with ombitasvir/paritaprevir/ritonavir at the Annual Meeting of the Japan Society of Hepatology in Kumamoto, Japan.

27 May 2015

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion, and are a "serious and growing issue." Each year two million people in the U.S. contract antibiotic-resistant infections, and at least 23,000 people die as a direct result.

27 May 2015

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

The team has completed two genomics studies on the tropical disease, a condition that is estimated to cause up to 30 million illnesses and over a quarter of a million deaths globally each year.

27 May 2015

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

By unlocking the secrets of a bizarre virus that survives in nearly boiling acid, scientists at the University of Virginia School of Medicine have found a blueprint for battling human disease using DNA clad in near-indestructible armor.

27 May 2015

Disease/Infection News

New ground-breaking initiative aims to find new treatments for leishmaniasis and Chagas disease

Scientists study active substance against dreaded hospital pathogen Staphylococcus aureus

Pennsylvania confirms first 2015 detections of West Nile Virus from mosquito sample

First European approval of drug to treat genetic kidney disease ADPKD

For World No-Tobacco Day WHO makes a stand against illicit tobacco trade

New TB-Profiler tool to find appropriate drugs for TB patients may improve likelihood of cure

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Researchers find weak spot in some antibiotic-resistant bacteria

Healthcare workers serve as vector for MRSA transmission in nursing home settings

Clinical trial suggests HIV patients should start therapy sooner rather than later

Research findings could help guide development of potential treatments for HCV

Earlier antiretroviral treatment benefits HIV-infected individuals

Actavis creates collaborative program to improve care for patients with multidrug-resistant infections

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

New tool could help identify pathogens in food and beverages

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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