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Genticel’s GTL001 phase 1 clinical study of HPV therapeutic vaccine granted FDA clearance

Genticel, a French biotechnology company and developer of innovative immunotherapies to prevent cancers caused by the human papillomavirus, today announces that the US Food and Drug Administration (FDA) has cleared Genticel’s Investigational New Drug application to conduct in the US a phase 1 clinical study of GTL001 in patients infected with HPV 16 and/or 18, the two HPV types responsible for 70% of cervical cancer cases.

16 Jun 2015

BiondVax invited to present at EDUFULVAC-NIAID workshop on immunoassay standardization for universal flu vaccines

BiondVax Pharmaceuticals Ltd., a clinical stage biopharmaceutical company focused on developing and commercializing immunomodulation therapies for infectious diseases,today announced that it has been invited to present in a workshop organized by EDUFULVAC, (EDUcate inFLUenza VACcine) a corresponding European Consortium coordinated by the European Vaccine Initiative (Germany) and NIAID (the National Instituteof Allergy and Infectious Diseases, a National Institute of Health branch) in the United States.

16 Jun 2015

Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

Pulmatrix, Inc., a clinical stage biopharmaceutical company developing innovative inhaled therapies for serious pulmonary diseases, today announced a new drug candidate, PUR1900, an inhaled anti-infective to treat fungal infections associated with cystic fibrosis (CF).

16 Jun 2015

HIV testing in Coventry, UK to become routine part of registering with GP

HIV testing in Coventry (UK) is to become a routine part of registering with a GP at ten surgeries across the city, which has the highest prevalence of the condition in the West Midlands.

16 Jun 2015

Vitamin D deficiency can leave people less able to fight HIV-1 infection

Vitamin D plays an important part in the human immune response and deficiency can leave individuals less able to fight infections like HIV-1. Now an international team of researchers has found that high-dose vitamin D supplementation can reverse the deficiency and also improve immune response.

16 Jun 2015

DSM Sinochem Pharmaceuticals supports WHO’s ‘Call to Action’ on antimicrobial resistance

Following the Global Health Summit in Uppsala (Sweden) on 2-3 June, 2015, DSM Sinochem Pharmaceuticals pledged its commitment to the WHO’s ‘Call to Action’ on antimicrobial resistance issued at the Summit. One of the biggest opportunities to maintain the effectiveness and availability of antibiotics is responsible waste management, to date a highly undervalued dimension in the debate around resistance. DSP promised to use its expertise and influence in this area to help curb antimicrobial resistance.

16 Jun 2015

Researchers uncover new mechanism that innate immune system uses to curb viral infections

An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical Centers in Mainz and Freiburg. Central to this is the discovery that two different but related elements of the immune system can act together in concert to fight, for example, rotavirus infections.

16 Jun 2015

Helmholtz Zentrum München scientists identify how Epstein-Barr virus conceals in human cells

Scientists at Helmholtz Zentrum München have now discovered how Epstein-Barr virus (EBV) conceals itself in human cells. A main culprit for its bad visibility by the immune system is the viral protein LMP2A. As published in the scientific journal PLOS Pathogens, the protein helps EBV-infected cells hide from T cells. This camouflage through the LMP2A protein may play a major role in the causation of cancer by EBV.

16 Jun 2015

Scientists develop new technique to analyze bacterial populations

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence. The new methods hold the promise of a potent new tool to offset the growing challenge of antibiotic resistance by bacterial pathogens.

16 Jun 2015

Better way to predict survival in patients with HPV-positive oropharyngeal cancer

According to Sturgis, the incidence of HPV-positive oropharyngeal carcinoma has increased dramatically in recent years. Although patients with HPV-positive disease have a better prognosis than those with HPV-negative disease, researchers are still seeking a better understanding of what group of patients is more likely to respond to treatment.

15 Jun 2015

Study shows bacteriophages remain active against P. aeruginosa infection after nebulization

bacteriophage-based antibacterial therapies to treat drug resistant infections, today announced new data demonstrating that bacteriophages remain active against Pseudomonas aeruginosa (P. aeruginosa) after nebulization.

15 Jun 2015

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that people with rheumatoid arthritis (RA) are less likely to be protected by hepatitis B vaccination than the general population.

14 Jun 2015

Researchers working on new system that can detect patient's antibiotic resistance in 30 minutes

A new device being developed by medical experts will transform the time it takes to detect antibiotic resistance in patients from several days to just half an hour.

12 Jun 2015

Researchers uncover how Gram-negative bacteria can trigger immune system reaction

Researchers at the University of Toronto have uncovered how Gram-negative bacteria -- a broad class of bugs that cause diseases ranging from gonorrhea to diarrhea and pneumonia -- can trigger a reaction from our immune system. This discovery could lead to new therapies and treatments that use the immune system to fight infections instead of antibiotics.

12 Jun 2015

Researchers identify two critical mutations that allow MERS virus to transmit from bats to humans

Researchers have identified two critical mutations allowing the deadly Middle East Respiratory Syndrome (MERS) virus to transmit from bats to humans. The findings were published in the most recent edition of the Journal of Virology.

11 Jun 2015

Patients with community-acquired pneumonia have high rates of long-term morbidity and mortality

Having had community-acquired pneumonia (CAP) greatly increases the risk of long-term morbidity and mortality compared to the general population who have never had CAP, according to a new study from researchers in Canada, the longest and largest outcomes study of patients with CAP reported to date.

11 Jun 2015

BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

BRIM Biotechnology, Inc., announced today that it has entered a Collaboration, Option and License Agreement with Janssen Pharmaceutica N.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

11 Jun 2015

Johns Hopkins researcher to help address solutions to antibiotic-resistant bacteria at White House

Johns Hopkins infectious disease researcher Sara Cosgrove, M.D., M.S., has been tapped by the White House to help address solutions to the ever-growing problem of antibiotic-resistant bacteria.

11 Jun 2015

ESCMID introduces two new study groups to create networks for forensic and veterinary microbiology

The European Society of Clinical Microbiology and Infectious Diseases launched two new study groups; the Forensic and Postmortem Microbiology Study Group and the Veterinary Microbiology Study Group.

11 Jun 2015

New method identifies harmful bacteria levels on recreational beaches

An international team, led by researchers at the University of Miami Rosenstiel School of Marine and Atmospheric Science, has developed a new, timelier method to identify harmful bacteria levels on recreational beaches. The new model provides beach managers with a better prediction tool to identify when closures are required to protect beachgoers from harmful contaminates in the water.

11 Jun 2015

Disease/Infection News

Genticel’s GTL001 phase 1 clinical study of HPV therapeutic vaccine granted FDA clearance

BiondVax invited to present at EDUFULVAC-NIAID workshop on immunoassay standardization for universal flu vaccines

Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

HIV testing in Coventry, UK to become routine part of registering with GP

Vitamin D deficiency can leave people less able to fight HIV-1 infection

DSM Sinochem Pharmaceuticals supports WHO’s ‘Call to Action’ on antimicrobial resistance

Researchers uncover new mechanism that innate immune system uses to curb viral infections

Helmholtz Zentrum München scientists identify how Epstein-Barr virus conceals in human cells

Scientists develop new technique to analyze bacterial populations

Better way to predict survival in patients with HPV-positive oropharyngeal cancer

Study shows bacteriophages remain active against P. aeruginosa infection after nebulization

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

Researchers working on new system that can detect patient's antibiotic resistance in 30 minutes

Researchers uncover how Gram-negative bacteria can trigger immune system reaction

Researchers identify two critical mutations that allow MERS virus to transmit from bats to humans

Patients with community-acquired pneumonia have high rates of long-term morbidity and mortality

BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

Johns Hopkins researcher to help address solutions to antibiotic-resistant bacteria at White House

ESCMID introduces two new study groups to create networks for forensic and veterinary microbiology

New method identifies harmful bacteria levels on recreational beaches

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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