Drug Discovery & Pharmaceuticals

RSS

New route for total synthesis of tetrodotoxin

In Japan, puffer fish is considered a delicacy, but the tickle to the taste buds comes with a tickle to the nerves: fugu contains tetrodotoxin, a strong nerve toxin.

6 Mar 2020

SFU researchers help discover potential new drug to kill superbugs

Researchers in Simon Fraser University's Brinkman Laboratory are collaborating with U.S. researchers to test a new drug that can kill a wide range of superbugs - including some bacteria now resistant to all common antibiotics.

3 Mar 2020

New tool shows potential to predict developmental toxicity in humans with high accuracy

Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc. demonstrated the platform's ability to predict developmental toxicity in humans with high accuracy using a cell-based test.

3 Mar 2020

WFIRM scientists develop miniature organ model to test drug toxicity

Scientists at the Wake Forest Institute for Regenerative Medicinehave developed the world's most sophisticated laboratory model of the human body, creating a system of miniaturized organs that can be used to detect harmful and adverse effects of drugs before they are prescribed to patients.

2 Mar 2020

Researchers develop multi-organ-on-a-chip for drug toxicity screening

Researchers in the US have developed a new multi-organ-on-a-chip to test how new drugs affect the human body's vital organs.

2 Mar 2020

Boehringer Ingelheim and Trutino enter into research collaboration to advance cytokine therapies

Boehringer Ingelheim and Trutino Biosciences today announced they have entered into a research collaboration and worldwide licensing agreement based on Trutino’s innovative On-Demand-Cytokine platform.

From Boehringer Ingelheim International GmbH 28 Feb 2020

McMaster researchers identify antibacterial compound made by cannabis plants

McMaster University researchers have identified an antibacterial compound made by cannabis plants that may serve as a lead for new drug development.

26 Feb 2020

CQDM and GlycoNet collaborate to support innovative glycomics research in Canada

CQDM and the Canadian Glycomics Network (GlycoNet) are pleased to announce they have formed a strategic partnership to identify and co-finance biopharmaceutical research projects in glycoscience across Canada.

25 Feb 2020

Essential oil components could meet the criteria set for drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates.

23 Feb 2020

Catalytic nanoreactors could simplify the manufacturing process of fine chemicals

The World Health Organization declared the novel coronavirus outbreak a 'Public Health Emergency of International Concern' on the 30th of January

22 Feb 2020

Isolating Single T-cells of Interest using an Optofluidic Platform

Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development.

From Bruker Cellular Analysis 21 Feb 2020

Active droplets for precise dosing of medication

Using a mixture of oil droplets and hydrogel, medical active agents can be not only precisely dosed, but also continuously administered over periods of up to several days. The active agents inside the droplets are released at a constant rate, decreasing the risk of over- or underdosage.

20 Feb 2020

StemBioSys announces acquisition of majority stake in Cartox

StemBioSys, Inc. and CarTox, Inc. are pleased to announce that StemBioSys has acquired a majority stake in Cartox. StemBioSys will acquire all remaining equity of Cartox subject to the achievement of certain milestones.

From StemBioSys 20 Feb 2020

SwRI's Rhodium evaluates drug compounds for possible treatment of coronavirus

Drug discovery software at Southwest Research Institute is expanding the capacity to virtually screen drug compounds for possible treatment of coronavirus and other infectious diseases.

20 Feb 2020

UPM joins Finnish research consortium to advance extracellular vesicle technologies

UPM has joined a newly formed Finnish research consortium that plans to use extracellular vesicles to develop novel nano-biotechnological solutions for the early diagnostics and treatment of severe progressive diseases.

19 Feb 2020

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

DuPont Nutrition & Biosciences today announced a collaboration with the MRM Health NV, a biopharmaceutical company, focused on the discovery and development of innovative therapeutics based on the human microbiome.

From DuPont 19 Feb 2020

Researchers discover antibiotics with unique approach to attacking bacteria

A new group of antibiotics with a unique approach to attacking bacteria has been discovered, making it a promising clinical candidate in the fight against antimicrobial resistance.

12 Feb 2020

New approach for organic synthesis may apply to drug discovery

After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery

12 Feb 2020

New therapeutic compounds could fight against brain-eating amoebae

Brain-eating amoebae can cause particularly harmful forms of encephalitis, and more than 95% of people who develop these rare but devastating infections die.

12 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Drug Discovery & Pharmaceuticals

New route for total synthesis of tetrodotoxin

SFU researchers help discover potential new drug to kill superbugs

New tool shows potential to predict developmental toxicity in humans with high accuracy

WFIRM scientists develop miniature organ model to test drug toxicity

Researchers develop multi-organ-on-a-chip for drug toxicity screening

Boehringer Ingelheim and Trutino enter into research collaboration to advance cytokine therapies

McMaster researchers identify antibacterial compound made by cannabis plants

CQDM and GlycoNet collaborate to support innovative glycomics research in Canada

Essential oil components could meet the criteria set for drug candidates

Catalytic nanoreactors could simplify the manufacturing process of fine chemicals

Isolating Single T-cells of Interest using an Optofluidic Platform

Active droplets for precise dosing of medication

StemBioSys announces acquisition of majority stake in Cartox

SwRI's Rhodium evaluates drug compounds for possible treatment of coronavirus

UPM joins Finnish research consortium to advance extracellular vesicle technologies

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

Researchers discover antibiotics with unique approach to attacking bacteria

New approach for organic synthesis may apply to drug discovery

New therapeutic compounds could fight against brain-eating amoebae

Scientists track down a potential target for new sleeping sickness drugs

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Latest Life Science News