Drug Discovery & Pharmaceuticals

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Researchers identify active stem cells in “resting zone” of cartilage

Researchers have discovered active chondrocytes within cartilage. The finding could help scientists understand bone abnormalities.

31 Oct 2018

New drug discovery will increase safety of canine sedation and anesthesia

A drug discovery made at the University of Helsinki's Faculty of Veterinary Medicine will increase the safety of animal sedation and anesthesia. Vatinoxan, the pharmacological molecule discovered in the study, reduced the adverse effects of other drugs on the cardiovascular system of canine patients.

31 Oct 2018

Game-changing microscope enables UK scientists to understand amyloid structure

Scientists have used cryo-electron microscopes to generate 3D images of amyloid, showing that aggregates form long, twisted fibers.

30 Oct 2018

Scientists discover kill code in all cells that can be triggered to destroy cancer

Researchers have discovered a kill code present within every cell of the body in the form of microRNAs that can cause cancerous cells to self-destruct

29 Oct 2018

Forced expression of a natural protein reduces fat in mice by a third

In a mouse model of obesity, forced expression of the protein FGFBP3 (BP3 for short) significantly reduced the animals’ fat mass.

29 Oct 2018

Neem Biotech granted two funding awards by Welsh Government for work in antimicrobial resistance

Neem Biotech’s work is boosted by two separate funding grants from the Welsh Government and European Regional Development Fund

From Neem Biotech 29 Oct 2018

Molecular breakthrough may improve prognosis for pancreatic cancer

Scientists have discovered a method by which fibroblasts in the stroma of pancreatic tumors can be reprogrammed to suppress tumor cell growth.

26 Oct 2018

New method for making mirrored forms of molecules

One of the biggest challenges facing synthetic chemists is how to make molecules of only a particular "handedness." Molecules can come in two shapes that mirror each other, just like our left and right hands.

26 Oct 2018

Researchers track where tetracycline antibiotics go in human cells

We know that antibiotics treat bacterial infections. We also know why they work. Tetracycline antibiotics, for example, stop bacteria from making protein. Like a boot on a wheel, the drugs bind to the bacterial cell's ribosome--where protein is made--and prevent it from working. Without protein, the bacteria weaken and die.

25 Oct 2018

Bioengineering scientists propose new paradigm for research into cardiovascular diseases

Thrombosis-on-a-chip, vasculature-on-a-chip and engineered models of human cardiac fibrosis are just a few of the new technologies revolutionizing research into human cardiovascular disease--a condition responsible for 17 million deaths per annum globally.

25 Oct 2018

Modeling Alzheimer’s Disease Using Microfluidics

An interview with Dr. Joseph Park, the incorporation of astrocytes into the Alzheimer’s-in-a-dish culture system and it's applications in drug development.

24 Oct 2018

How a single mutation can devastate cellular function

A scientist has shown how a single mutation in a protein found in astrocytes reproduces fibrous globs that devastate cellular function.

23 Oct 2018

Gut microbiota at infancy predict risk of obesity in later life

Researchers have provided further evidence to support the link between the gut microbiota in infancy and the risk of becoming overweight or obese in later life

23 Oct 2018

Epigenetic modifications may contribute to Alzheimer's Disease

Scientists report epigenetic modifications in the brains of patients with Alzheimer's, after observing differences in histone acetylation across the genome.

22 Oct 2018

New protein sequencing technique could revolutionize biomedical research

Scientists have developed a new, low-throughput technique that allows individual proteins to be identified. It is called single molecule fluorosequencing.

22 Oct 2018