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Drug treatment reduces gout flares in clinical study

As reported in the journal Arthritis & Rheumatology, the drug febuxostat reduced gout flares in a double-blind, placebo-controlled study of 314 adults with early gout.

4 Oct 2017

Study sheds light on the mechanism of lung damage in premature babies

The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.

30 Sep 2017

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Historically, randomized controlled trials have served as the state-of-the-art method for determining the efficacy and safety of new, innovative treatment regimens for patients with cancer and other diseases.

28 Sep 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Study shows benefits of delayed-release stimulant in children with ADHD

A phase 3 study of children ages 6-12 years with attention deficit/hyperactivity disorder (ADHD) has shown that a delayed-release, long-acting formulation of the stimulant methylphenidate, when taken in the evening, led to significant improvement in ADHD symptoms and functional impairment first thing the next morning, compared to a placebo.

27 Sep 2017

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen -- an antisense oligomer that inhibits the production of certain influenza proteins -- is safe and well-tolerated in healthy individuals.

20 Sep 2017

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

Ramucirumab plus docetaxel improves progression-free survival in patients with advanced or metastatic urothelial cancer who have progressed on platinum-based chemotherapy, according to late-breaking results from the phase III RANGE trial presented today at the ESMO 2017 Congress in Madrid to be published in The Lancet.

14 Sep 2017

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes.

13 Sep 2017

Insmed reports top-line data from Phase 3 study of new treatment in patients with NTM lung disease

Insmed Incorporated, a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced top-line data from its Phase 3 CONVERT study.

13 Sep 2017

Tulane University researchers develop new drug effective against malaria

Tulane University researchers have developed a new drug that is effective against non-severe cases of malaria, according to results from an FDA-supervised clinical trial published in the latest issue of The Lancet Infectious Diseases.

13 Sep 2017

$New medication shows potential to reduce fracture risk in women with osteoporosis$

New medication shows potential to reduce fracture risk in women with osteoporosis

A new drug that boosts bone formation has been shown to reduce the risk of fracture in women with osteoporosis when compared to one of the most commonly used osteoporosis medications.

12 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Australian researchers make ultimate move in the battle against melanoma

A team of Australian researchers has made the ultimate move in the battle to beat melanoma, successfully trialing a combination of new treatments to stop the disease in its tracks and prevent it from spreading or metastasizing to distant organs.

12 Sep 2017

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Combination targeted adjuvant therapy with dabrafenib and trametinib doubles relapse-free survival in patients with stage III BRAF-mutant melanoma, according to late-breaking results from the COMBI-AD trial presented today at the ESMO 2017 Congress in Madrid and published in the New England Journal of Medicine.

11 Sep 2017

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Combination immunotherapy as second or third line treatment extends overall survival to at least 15 months in patients with pleural malignant mesothelioma, according to late-breaking results from the MAPS2 trial presented today at the ESMO 2017 Congress in Madrid.

11 Sep 2017

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Two new treatments may benefit patients with high risk prostate cancer, trial shows

Patients with high risk prostate cancer starting long-term hormone therapy may benefit from two new treatments, according to late-breaking results from the STAMPEDE trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

The superiority of docetaxel based triplet therapy over standard care in patients with resectable oesophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Drug Trial News

Drug treatment reduces gout flares in clinical study

Study sheds light on the mechanism of lung damage in premature babies

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Trial identifies genetic fault that affects treatment response in leukemia patients

Study shows benefits of delayed-release stimulant in children with ADHD

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

Insmed reports top-line data from Phase 3 study of new treatment in patients with NTM lung disease

Tulane University researchers develop new drug effective against malaria

New medication shows potential to reduce fracture risk in women with osteoporosis

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Australian researchers make ultimate move in the battle against melanoma

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Two new treatments may benefit patients with high risk prostate cancer, trial shows

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

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