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New clinical study aims to prevent onset of epilepsy in children with tuberous sclerosis

A clinical trial of a drug that researchers hope can prevent or delay the onset of epilepsy in children with tuberous sclerosis has begun at McGovern Medical School at The University of Texas Health Science Center at Houston.

8 May 2017

FDA approves new AML drug after clinical testing at Dana-Farber

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

5 May 2017

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

The disease is characterized by inflammation and a buildup of tissue around the eyes that cause them to bulge painfully from their sockets.

4 May 2017

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Researchers have discovered that a new anti-rejection drug that is gentler on the kidneys after liver transplant also reduces weight gain, which is common after surgery and can lead to serious complications for transplant patients.

3 May 2017

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Merck announced the presentation of new analyses of efficacy and safety data for investigational Cladribine Tablets in poster presentations at the Annual Meeting of the American Academy of Neurology (AAN), that took place April 22 – 28, 2017, in Boston, Massachusetts.

3 May 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

New study aims to test safety and efficacy of antiplatelet drug in preventing blood clots

A new clinical study is starting at the German Centre for Cardiovascular Research (DZHK) with an innovative and highly specific blood thinner.

28 Apr 2017

VUMC researcher receives grant to test efficacy of drug for reversing precancerous stomach lesions

Vanderbilt University Medical Center cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions.

28 Apr 2017

Clinical trial discovers drug combination that could help children with arthritis

A clinical trial funded by Arthritis Research UK and the National Institute for Health Research led by professors from the Universities of Liverpool and Bristol has discovered a drug combination that could help thousands of children with arthritis.

27 Apr 2017

Drug shows early promise in treating patients with small-cell lung cancer

An early round of clinical testing shows that users of Opdivo, a drug sanctioned for treatment of small-cell lung cancer, more than tripled their five-year survival rate beyond the statistical average.

20 Apr 2017

CIRM funds clinical study to test safety, efficacy of new retinitis pigmentosa treatment

Cell therapy company jCyte is launching a phase 2b clinical trial to test the safety and efficacy of its developmental retinitis pigmentosa (RP) treatment, jCell.

19 Apr 2017

Cannabidiol shows promise to reduce seizures for people with difficult-to-treat epilepsy

Taking cannabidiol may cut seizures in half for some children and adults with Lennox-Gastaut syndrome (LGS), a severe form of epilepsy, according to new information released today from a large scale controlled clinical study that will be presented at the American Academy of Neurology's 69th Annual Meeting in Boston, April 22 to 28, 2017.

19 Apr 2017

UTHealth participates in study to evaluate effectiveness of new injectable HIV medication

The HIV Prevention Trials Network, which includes McGovern Medical School at The University of Texas Health Science Center at Houston, has launched a study to evaluate whether a new injectable medication can work as well as an existing oral pill to safely protect against HIV among men who have sex with men (MSM) and transgender women (TGW) who have sex with men.

18 Apr 2017

New drug compound could cut number of hot flushes in menopausal women

Women plagued by frequent hot flushes during the menopause could cut the number of flushes by almost three-quarters, thanks to a new drug compound.

3 Apr 2017

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

The University of Miami Miller School of Medicine will soon begin one of the nation's first full-scale Zika vaccine clinical trials testing the National Institutes of Health's (NIH) experimental DNA-based vaccine.

31 Mar 2017

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Bayer today announced positive data on its investigational compound copanlisib, an intravenous pan-Class I phosphatidylinositol-3-kinase (PI3K) inhibitor with predominant inhibitory activity against PI3K-α and PI3K-δ isoforms.

31 Mar 2017

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Novocure announced today results from the second cohort of its phase 2 pilot PANOVA trial studying Tumor Treating Fields (TTFields) in combination with nab-paclitaxel and gemcitabine for the treatment of advanced pancreatic cancer.

31 Mar 2017

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Novocure announced today results from its phase 2 pilot INNOVATE trial studying Tumor Treating Fields (TTFields) in combination with weekly paclitaxel for the treatment of recurrent ovarian cancer.

31 Mar 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

Drug Trial News

New clinical study aims to prevent onset of epilepsy in children with tuberous sclerosis

FDA approves new AML drug after clinical testing at Dana-Farber

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Takeda announces accelerated approval from FDA for new lung cancer treatment

New study aims to test safety and efficacy of antiplatelet drug in preventing blood clots

VUMC researcher receives grant to test efficacy of drug for reversing precancerous stomach lesions

Clinical trial discovers drug combination that could help children with arthritis

Drug shows early promise in treating patients with small-cell lung cancer

CIRM funds clinical study to test safety, efficacy of new retinitis pigmentosa treatment

Cannabidiol shows promise to reduce seizures for people with difficult-to-treat epilepsy

UTHealth participates in study to evaluate effectiveness of new injectable HIV medication

New drug compound could cut number of hot flushes in menopausal women

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

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