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Study shows efficacy of antipsychotic as adjunctive therapy for gastroparesis in emergency department

Haloperidol is an effective first-line agent in combination with standard analgesic and antiemetic agents for the treatment of gastroparesis in the emergency department.

26 Oct 2017

New molecule could become first treatment against chemotherapy-induced neuropathy

IDIBELL Researchers of the Neuro-Oncology Unit of Bellvitge University Hospital - Catalan Institute of Oncology, led by Dr. Jordi Bruna, have successfully tested a new molecule capable of preventing the development of peripheral neuropathy induced by chemotherapy in cancer patients, especially in colon cancer cases, the third most common neoplasm in the world.

24 Oct 2017

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

Stand Up To Cancer has awarded a $2.5 million SU2C CatalystR grant to the Translational Genomics Research Institute to investigate a revolutionary new method of treating pancreatic cancer, one of the most aggressive of all cancers.

13 Oct 2017

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Rettsyndrome.org is pleased to share that Neuren Pharmaceuticals, today, after meeting with the FDA, will conduct a Phase 3 clinical trial for trofinetide, a compound that shows great promise in the treatment of Rett syndrome, in children and adults.

13 Oct 2017

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

Salk Professor and HHMI Investigator Ronald Evans has been awarded $2.5 million by Stand Up 2 Cancer (SU2C) as part of a multi-institution team to conduct clinical studies to open up a new avenue for immunotherapy in the treatment of pancreatic cancer.

12 Oct 2017

Clinical trial tests frankincense as potential breast, colon cancer treatment

Cancer surgeon and researcher Nancy DeMore is leading a clinical trial using frankincense to try to treat breast and colon cancer at the Medical University of South Carolina. The study was inspired by a research specialist in DeMore's lab.

11 Oct 2017

Allergy medication restores nervous system function in patients with chronic MS

In a remarkably rapid translation of laboratory research findings into a treatment with the potential to benefit patients, UC San Francisco scientists have successfully completed a Phase II clinical trial showing that an FDA-approved antihistamine restores nervous system function in patients with chronic multiple sclerosis (MS).

11 Oct 2017

TB Alliance announces phase 1 clinical trials of two novel tuberculosis drugs

TBA-7371 and sutezolid entered phase 1 clinical trials, TB Alliance announced today. Both compounds have proceeded through early preclinical development and were granted "Investigative New Drug" status by the U.S. Food and Drug Administration. The phase 1 clinical trials are presently ongoing.

11 Oct 2017

NYU Dentistry awarded grant to test impact of simple treatment on cavity progression

The National Institute of Dental & Craniofacial Research, part of the National Institutes of Health, has awarded a grant that will provide funding to New York University College of Dentistry and its collaborators to test the effectiveness of silver diamine fluoride in stopping the progression of cavities in young children.

10 Oct 2017

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

The National Institute of Allergy and Infectious Disease of the National Institutes of Health awarded more than $2 million to a research team at the George Washington University School of Medicine and Health Sciences to facilitate a Zika vaccine trial in Brazil.

9 Oct 2017

Ebola vaccine found to be safe and effective for adults and children in Africa

Experts at St George's, University of London, have reported that an Ebola vaccine is safe for children as well as adults and produces an immune response.

6 Oct 2017

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans, according to new research from the Perelman School of Medicine at the University of Pennsylvania, conducted in partnership with The Wistar Institute, Inovio Pharmaceuticals, and GeneOne Life Science, Inc.

5 Oct 2017

'First-in-man' clinical trial protocols often not guided by pharmacology, analysis shows

A new analysis published in the British Journal of Clinical Pharmacology indicates that 'first-in-man' clinical trial protocols in the Netherlands often lack a consistent consideration of pharmacokinetic and pharmacodynamic aspects in establishing drug doses.

4 Oct 2017

Drug treatment reduces gout flares in clinical study

As reported in the journal Arthritis & Rheumatology, the drug febuxostat reduced gout flares in a double-blind, placebo-controlled study of 314 adults with early gout.

4 Oct 2017

Study sheds light on the mechanism of lung damage in premature babies

The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.

30 Sep 2017

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Historically, randomized controlled trials have served as the state-of-the-art method for determining the efficacy and safety of new, innovative treatment regimens for patients with cancer and other diseases.

28 Sep 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Study shows benefits of delayed-release stimulant in children with ADHD

A phase 3 study of children ages 6-12 years with attention deficit/hyperactivity disorder (ADHD) has shown that a delayed-release, long-acting formulation of the stimulant methylphenidate, when taken in the evening, led to significant improvement in ADHD symptoms and functional impairment first thing the next morning, compared to a placebo.

27 Sep 2017

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen -- an antisense oligomer that inhibits the production of certain influenza proteins -- is safe and well-tolerated in healthy individuals.

20 Sep 2017

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

Ramucirumab plus docetaxel improves progression-free survival in patients with advanced or metastatic urothelial cancer who have progressed on platinum-based chemotherapy, according to late-breaking results from the phase III RANGE trial presented today at the ESMO 2017 Congress in Madrid to be published in The Lancet.

14 Sep 2017

Drug Trial News

Study shows efficacy of antipsychotic as adjunctive therapy for gastroparesis in emergency department

New molecule could become first treatment against chemotherapy-induced neuropathy

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

Clinical trial tests frankincense as potential breast, colon cancer treatment

Allergy medication restores nervous system function in patients with chronic MS

TB Alliance announces phase 1 clinical trials of two novel tuberculosis drugs

NYU Dentistry awarded grant to test impact of simple treatment on cavity progression

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

Ebola vaccine found to be safe and effective for adults and children in Africa

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

'First-in-man' clinical trial protocols often not guided by pharmacology, analysis shows

Drug treatment reduces gout flares in clinical study

Study sheds light on the mechanism of lung damage in premature babies

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Trial identifies genetic fault that affects treatment response in leukemia patients

Study shows benefits of delayed-release stimulant in children with ADHD

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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