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Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Three clinical trials led by researchers at The University of Texas MD Anderson Cancer Center demonstrated positive results from the targeted therapy erdafitinib for patients with multiple tumor types harboring FGFR alterations.

5 Jun 2023

SWOG Cancer Research Network clinical trial reveals potential new therapy for Stage 3 or 4 classic Hodgkin lymphoma

A Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment with nivolumab, a PD-1 checkpoint inhibitor, and AVD chemotherapy (N-AVD) had a significantly lower risk of their cancer getting worse than patients treated with brentuximab vedotin, a monoclonal antibody, and AVD (BV-AVD) a year after starting treatment.

4 Jun 2023

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Updated dose expansion data of the phase I STRO-002-GM1 study have been presented today by Ana Oaknin, Principal Investigator of the Vall d'Hebron Institute of Oncology's (VHIO) Gynecological Malignancies Group, on the ground at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO), 2-6 June in Chicago, USA.

4 Jun 2023

Study of immunotherapy for brain cancer metastases shows promising results

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving longer than two years.

2 Jun 2023

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Lupus Therapeutics announced the start of a collaboration to conduct three Phase 3 clinical trials testing an investigational therapeutic ianalumab for systemic lupus erythematosus and lupus nephritis.

2 Jun 2023

Eye drops to slow the progression of nearsightedness in kids could be on the horizon

The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon.

1 Jun 2023

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles.

1 Jun 2023

Treatment with modified lactic acid bacteria accelerates the healing of wounds, study shows

Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy.

30 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Treatment with luspatercept improved red blood cell counts and erythroid responses compared to treatment with epoetin alfa in patients with myelodysplastic syndromes (MDS), allowing the majority to no longer require regular blood transfusions.

26 May 2023

New treatment protocol for brain hemorrhage improves survival chances without major disability

The George Institute for Global Health today announced data from the phase III INTERACT3 study demonstrating that a new combination of treatments for stroke due to intracerebral hemorrhage (ICH) significantly improves the chances of surviving without major disability.

26 May 2023

Novel vaccine offers hope for defeating epidemic meningitis by 2030

A trial of a new vaccine against meningococcal disease, a cause of meningitis and blood poisoning, has found that it is safe and induces a strong immune response across five strains of meningococcal bacteria: A, C, W, Y and X.

25 May 2023

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

25 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Researchers assessed the safety and efficacy of danuglipron in type 2 diabetes (T2D) patients.

24 May 2023

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

An international clinical trial co-led by UCL (University College London) researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis.

23 May 2023

First vaccine against Lyme disease is now being tested in Sweden

A vaccine against Lyme disease is now being tested in Sweden, for the first time ever. A new vaccine will probably be on the market within a couple of years, says Johan Sanmartin Berglund, Professor of applied health technology at Blekinge Institute of Technology.

23 May 2023

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

Transthyretin-related cardiac amyloidosis is a progressive disease characterized by the deposition of amyloid protein fibrils in the heart. Amyloid fibril deposition thickens and stiffens the heart walls, and the disease is also known as stiff-heart syndrome.

22 May 2023

New clinical trial gets underway to evaluate new antibiotic combinations for newborns with sepsis

An international clinical trial to evaluate much-needed new antibiotic combinations for newborn babies with sepsis has started in three public hospitals in South Africa and Kenya.

22 May 2023

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Sacubitril/valsartan leads to greater reduction in plasma NT-proBNP levels compared to valsartan alone after stabilization for worsening heart failure in patients with an ejection fraction (EF) above 40%, according to late breaking science presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC), and published in the Journal of the American College of Cardiology.

22 May 2023

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Drug Trial News

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

SWOG Cancer Research Network clinical trial reveals potential new therapy for Stage 3 or 4 classic Hodgkin lymphoma

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Study of immunotherapy for brain cancer metastases shows promising results

Lupus Therapeutics announces three Phase 3 clinical trials testing new therapies for SLE and lupus nephritis

Eye drops to slow the progression of nearsightedness in kids could be on the horizon

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Treatment with modified lactic acid bacteria accelerates the healing of wounds, study shows

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

New treatment protocol for brain hemorrhage improves survival chances without major disability

Novel vaccine offers hope for defeating epidemic meningitis by 2030

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

First vaccine against Lyme disease is now being tested in Sweden

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

New clinical trial gets underway to evaluate new antibiotic combinations for newborns with sepsis

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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