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Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Donanemab may offer new hope for people with early Alzheimer's disease

The data reported today by Eli Lilly from the TRAILBLAZER-ALZ 2 clinical trial of donanemab in early symptomatic Alzheimer's disease demonstrate an important advancement in Alzheimer's research and treatment.

17 Jul 2023

PALACE study: Direct oral challenge can safely remove penicillin allergy label

Penicillin allergy affects more than 25 million people in the United States (up to 1 in 10 Americans) and has been shown to lead to particularly poor health outcomes in pregnant women and surgical patients. It is also a public health threat, leading to antibiotic resistance and infections in hospitalized patients that can be life threatening.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023

Exploring the efficacy of topical lidocaine in individuals with chronic neck pain

A team of researchers investigated the efficacy of lidocaine for the treatment of neck pain.

17 Jul 2023

NIH funding for phased clinical trials represents <3.5% of total spending

The U.S. National Institutes of Health (NIH) contributed $8.1 billion in project funding for phased clinical trials involving drugs approved by the FDA from 2010-2019, according to a new study from Bentley University's Center for Integration of Science and Industry.

14 Jul 2023

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in the tumor microenvironment.

12 Jul 2023

Cytisinicline could offer adult cigarette smokers a potential new treatment option

The first large-scale U.S. clinical trial of cytisinicline, led by a Massachusetts General Hospital (MGH) investigator, found the smoking cessation medication to be effective and well tolerated in adults who wished to break their nicotine dependence.

11 Jul 2023

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.

5 Jul 2023

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

4 Jul 2023

PSI-developed drug could increase survival chances for metastatic prostate cancer patients

Researchers at PSI have developed a new drug that could increase the survival chances of patients with metastatic prostate cancer.

4 Jul 2023

Growth factor study reveals potential breakthrough in obesity management

Study discusses the effects of a growth factor that showed promising results in mice in an obesity trial.

4 Jul 2023

Tirzepatide triumphs in significant weight reduction for people with type 2 diabetes

Researchers performed a double-blinded, placebo-controlled phase III randomized clinical trial (RCT).

29 Jun 2023

The Lancet study unveils exciting findings on retatrutide as a novel treatment for type 2 diabetes

Researchers performed a phase II randomized clinical trial (RCT).

29 Jun 2023

Study reveals oral Semaglutide 50 mg as promising treatment for obesity in adults: the Lancet report

Researchers performed a phase III randomized clinical trial (RCT).

29 Jun 2023

Trial shows no benefit of prescribing an opioid for people with acute back or neck pain

Opioid pain-relieving medicines are not more effective than a placebo in relieving acute back and neck pain and may even cause harm, according to a world-first trial led by the University of Sydney.

28 Jun 2023

New drug effective as a treatment against ulcerative colitis, clinical trial shows

A new drug, investigated by Amsterdam UMC together with colleagues around the world, is effective as a treatment against ulcerative colitis.

28 Jun 2023

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

Clinical testing is underway for a potentially groundbreaking new treatment for cystic fibrosis. Pioneered by scientists at Carle Illinois College of Medicine at the University of Illinois Urbana-Champaign and the Carver College of Medicine at the University of Iowa in partnership with the spin-out biotechnology company, cystetic Medicines, this promising inhalable molecular prosthetic is intended to improve lung function in people with CF who cannot benefit from current therapies.

26 Jun 2023

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Drug Trial News

Donanemab: A trailblazer for Alzheimer's disease treatment?

Donanemab may offer new hope for people with early Alzheimer's disease

PALACE study: Direct oral challenge can safely remove penicillin allergy label

Donanemab shows promise in slowing Alzheimer's disease

Exploring the efficacy of topical lidocaine in individuals with chronic neck pain

NIH funding for phased clinical trials represents <3.5% of total spending

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

Cytisinicline could offer adult cigarette smokers a potential new treatment option

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

PSI-developed drug could increase survival chances for metastatic prostate cancer patients

Growth factor study reveals potential breakthrough in obesity management

Tirzepatide triumphs in significant weight reduction for people with type 2 diabetes

The Lancet study unveils exciting findings on retatrutide as a novel treatment for type 2 diabetes

Study reveals oral Semaglutide 50 mg as promising treatment for obesity in adults: the Lancet report

Trial shows no benefit of prescribing an opioid for people with acute back or neck pain

New drug effective as a treatment against ulcerative colitis, clinical trial shows

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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