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New type of drug significantly increases survival of bladder cancer patients

A new type of drug that helps target chemotherapy directly to cancer cells has been found to significantly increase survival of patients with the most common form of bladder cancer, according to results from a phase III clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust.

13 Feb 2021

Pediatric trial results show rabies treatment is safe and effective in children

A treatment, known as KEDRAB (Rabies Immune Globulin [Human]), currently used in the prevention of rabies has been demonstrated to be safe and effective for patients age 17 and under.

10 Feb 2021

Both mRNA vaccines protect against emerging variants of SARS-CoV-2

Researchers in the United States and Canada have conducted a study showing that just a single dose of either the Pfizer-BioNTech or Moderna vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is likely to protect against emerging variants.

9 Feb 2021

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

McMaster University researchers are leading a large international study to test drugs to treat COVID-19 patients.

9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized.

8 Feb 2021

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world.

6 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Researchers call for trials of rapamycin to treat COVID-19

Researchers in the United States, China, and the UK have called for immediate large-scale clinical trials of an antibiotic called rapamycin as a prophylactic and treatment approach to coronavirus disease 2019 (COVID-19) in older individuals.

4 Feb 2021

Phase I/II trial findings support use of CoronaVac vaccine in older individuals

Researchers in China have reported phase I/II clinical trial findings showing that the vaccine candidate CoronaVac is well tolerated among older individuals and effectively generates antibody responses against severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19).

4 Feb 2021

New drug candidate to be trialed for most lethal form of brain cancer

A new drug candidate has been discovered by the University of South Australia to treat the most lethal form of brain cancer - glioblastoma - which kills 95 per cent of patients within five years.

4 Feb 2021

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

A new study offers some reassuring findings, reporting the successful neutralization of the South African SARS-CoV-2 variant of concern (VOC) 501Y.V2 by two vaccines developed in China.

4 Feb 2021

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

A new study reports the underlying basis of increased transmissibility in the N501Y UK variant and provides reassuring data on the efficacy of the Pfizer vaccine and Eli Lilly monoclonal antibodies in neutralizing it.

4 Feb 2021

Russia's Sputnik V COVID-19 shown to have 91.6 percent efficacy

The phase 3 human trial is the last stage of clinical evaluation, showing how effective and safe a drug or vaccine is. In this case, the Gam- Sputnik V showed a consistent strong protective effect across all participant age groups.

3 Feb 2021

Nasodine antiseptic nasal spray shows potential antiviral activity against SARS-CoV-2

A team of international scientists has recently investigated the efficacy of PVP-1, a complex of polyvinylpyrrolidone and iodine, in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Using in vitro cell culture settings, the scientists observe that PVP-1 formulation used in a commercially available nasal spray (Nasodine) readily inactivates SARS-CoV-2 within a short period of time.

3 Feb 2021

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

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Drug Trial News

New type of drug significantly increases survival of bladder cancer patients

Pediatric trial results show rabies treatment is safe and effective in children

Both mRNA vaccines protect against emerging variants of SARS-CoV-2

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

A precursor to remdesivir shows therapeutic potential for COVID-19

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Researchers call for trials of rapamycin to treat COVID-19

Phase I/II trial findings support use of CoronaVac vaccine in older individuals

New drug candidate to be trialed for most lethal form of brain cancer

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

Russia's Sputnik V COVID-19 shown to have 91.6 percent efficacy

Nasodine antiseptic nasal spray shows potential antiviral activity against SARS-CoV-2

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Latest clinical trial supports UK’s decision to delay second COVID vaccine dose

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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