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Trial results support efficacy of incentivizing vaccine adherence

As the United States struggles to control record-breaking increases in COVID-19 infections and hospitalizations, the roll-out of two approved vaccines offers tremendous hope for saving lives and curbing the pandemic.

22 Jan 2021

New pain management regimen reduced opioid exposure in trauma patients

A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth).

22 Jan 2021

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML) are rare hematologic malignancies of the bone marrow.

21 Jan 2021

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Study shows antidepressant drugs are largely ineffective for back and osteoarthritis pain

Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence published by The BMJ today.

20 Jan 2021

Antidepressants are not effective for treating back pain, osteoarthritis, shows study

Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm.

20 Jan 2021

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by erythematous (red) patches and plaques.

19 Jan 2021

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

A small pilot study suggests that early administration of ivermectin can reduce viral loads and symptom duration in patients with mild COVID-19, which in turn could help reduce viral transmission.

19 Jan 2021

Green Mediterranean diet reduces non-alcoholic fatty liver disease, show randomized trials

A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term clinical intervention trial led by Ben-Gurion University of the Negev researchers and a team of international colleagues.

18 Jan 2021

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

A clinical trial involving COVID-19 patients hospitalized at UT Health San Antonio and University Health, among roughly 100 sites globally, found that a combination of the drugs baricitinib and remdesivir reduced time to recovery, according to results published Dec. 11 in the New England Journal of Medicine.

16 Jan 2021

New drug reduces tumor volume and pain in patients with neurofibromatosis type 1

Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Children's Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).

15 Jan 2021

MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

A new study reports the preclinical testing of a recombinant MVA (rMVA) candidate vaccine against SARS-CoV-2, the agent that is causing the current COVID-19 pandemic.

14 Jan 2021

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress s to expand the Phase II clinical trial at The University of Texas Health Science Center at HoustonQ.

13 Jan 2021

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

A new study confirms that treatment with Bimagrumab, an antibody that blocks activin type II receptors and stimulates skeletal muscle growth, is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and type 2 diabetes.

13 Jan 2021

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood around the body as it contracts).

13 Jan 2021

Lactating women should discuss risks and benefits of COVID-19 vaccination, says ABM

The Academy of Breastfeeding Medicine (ABM) does not recommend cessation of breastfeeding for individuals who are vaccinated against COVID-19.

13 Jan 2021

Study shows COVID-19 pneumonia is different from typical pneumonia

Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung over the course of hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body's immune system within the first few days of the illness.

12 Jan 2021

C-Path PRO Consortium measure now included in FDA-approved label claim

Critical Path Institute's (C-Path) Patient-Reported Outcome (PRO) Consortium announces that clinical study results using the Consortium's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) were recently included in the expanded label for the drug LINZESS® (linaclotide).

7 Jan 2021

Study: Antibiotics are not necessary after most endoscopic sinus surgeries

Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.

6 Jan 2021

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

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Drug Trial News

Trial results support efficacy of incentivizing vaccine adherence

New pain management regimen reduced opioid exposure in trauma patients

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Study shows antidepressant drugs are largely ineffective for back and osteoarthritis pain

Antidepressants are not effective for treating back pain, osteoarthritis, shows study

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

Green Mediterranean diet reduces non-alcoholic fatty liver disease, show randomized trials

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

New drug reduces tumor volume and pain in patients with neurofibromatosis type 1

MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Lactating women should discuss risks and benefits of COVID-19 vaccination, says ABM

Study shows COVID-19 pneumonia is different from typical pneumonia

C-Path PRO Consortium measure now included in FDA-approved label claim

Study: Antibiotics are not necessary after most endoscopic sinus surgeries

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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