Genomics

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RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

At a time when the previously untapped drug discovery opportunity promised within RNA opens up, the 2nd RNA- Targeted Drug Discovery Summit returns to reunite the leading minds from large pharma, innovative biotech and KOLs of academia to overcome unique discovery and development challenges associated with novel RNA targeted small molecule therapeutics and achieve their seemingly limitless potential.

From RNA-Targeted Drug Discovery Summit 30 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Anxiety-related behavior associated with disturbances in the cells' powerhouses

The powerhouse of the cell, the mitochondria, provides energy for cellular functions. But those activities can become disturbed when chronic stress leads to anxiety symptoms in mice and humans.

26 Sep 2019

Multiple sclerosis genomic map implicates immune cells in disease susceptibility

The International Multiple Sclerosis Genetic Consortium reports the results of its latest study, "Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility", in the journal Science today: the highly productive collaborative group presents a new milestone in its efforts to understand the genetic basis of multiple sclerosis.

26 Sep 2019

Researchers identify novel genetic variants linked to plasma lipid levels and cardiovascular risk

An international research team has identified several novel genetic variants associated with plasma levels of lipid species and cardiovascular disease risk in humans.

26 Sep 2019

Personal Genome Diagnostics applies CE mark to PGDx elio tissue complete assay

Personal Genome Diagnostics Inc. (PGDx), a leader in cancer genomics, today announced that it has applied the CE mark to the PGDx elio™ tissue complete assay.

26 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Improved mapping of genomes from 1,000 Swedish individuals

In so-called whole genome sequencing, surveys are made of the total genome of an individual. It is still relatively rare in healthcare today, but it occurs at an increasing rate, for example in order to make an accurate diagnosis in the case of a rare disease.

25 Sep 2019

Native American DNA is still carried by descendants of early Europeans and Africans in the U.S.

Many people in the U.S. do not belong to Native American communities but still carry bits of Native American DNA, inherited from European and African ancestors who had children with indigenous individuals during colonization and settlement.

From PLOS ONE 25 Sep 2019

Study uncovers new DNA sequences in Swedish genomes

People - or more specifically just Swedes - are more like chimpanzees than previously known. This is indicated in a genetic mapping of one thousand Swedish individuals, where new DNA sequences that should be included in the reference genome have been identified.

24 Sep 2019

Iranian population is highly heterogeneous than previously believed, genome study shows

An international research team including scientists from the University of Cologne, Germany, numerous Iranian universities and the University of Sydney, Australia, has shown that today's Iranian population is composed of partially highly heterogeneous ethnic groups, exhibiting a high degree of genetic variation.

24 Sep 2019