Genomics

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Study illuminates the role of HAND2 gene in timing of human labor

A new study illuminates how a gene called HAND2 may have a hand in the timing of human labor.

22 Feb 2021

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Long-term sleep deprivation is detrimental to health, increasing the risk of psychiatric and somatic disorders, such as depression and cardiovascular diseases.

22 Feb 2021

Researchers use functional test to measure the effect of inherited variants in BRCA2 cancer gene

Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS).

20 Feb 2021

Scientists describe genetic mechanisms behind mating process of ciliates

Conjugation (or mating) of ciliates is a unique phenomenon among living beings. They have sex not for reproduction or pleasure — they seek to increase genetic variation.

20 Feb 2021

Direct cloning method aims to accelerate large-scale discovery of novel natural products

Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications.

20 Feb 2021

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

20 Feb 2021

Uninherited genetic mutations can cause spina bifida

Genetic mutations which occur naturally during the earliest stages of an embryo's development can cause the severe birth defect spina bifida, finds a new experimental study in mice led by UCL scientists.

19 Feb 2021

Trispecific antibody targets cancer cells, natural killer cells

Several treatments for cancer have been devised by science, but unfortunately none of them are completely efficient or foolproof.

19 Feb 2021

Study of newlyweds suggests a possible genetic link to marriage satisfaction

Variation in a specific gene could be related to traits that are beneficial to bonding and relationship satisfaction in the first years of a marriage, according to a new study by a University of Arkansas psychologist.

18 Feb 2021

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer.

18 Feb 2021

Researchers find a way to improve deletion efficiency of new genome-editing tool

CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision.

17 Feb 2021

People with ADHD and DBDs share genetic variants associated with risky behaviors

People with attention-deficit / hyperactivity disorder (ADHD) combined with disruptive behaviour disorders (DBDs) share about the 80% of genetic variants associated with aggressive and antisocial behaviors.

17 Feb 2021

Genetic variant inherited from Neanderthals associated with protection against severe COVID-19

SARS-CoV-2, the virus that causes COVID-19, impacts people in different ways after infection. Some experience only mild or no symptoms at all while others become sick enough to require hospitalization and may develop respiratory failure and die.

16 Feb 2021

Study outlines the reasons to test pediatric cancer patients for inherited genes

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

16 Feb 2021

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

16 Feb 2021

Study highlights the epigenetics of life at high altitudes

Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth.

16 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

Male fruit flies win genetic race with rivals in post-mating fertilization game

Scientists have accepted natural selection as a driver of evolution for more than 160 years, thanks to Charles Darwin

15 Feb 2021

Scientists identify genes involved in autoimmune Addison's disease

Novel genetic associations could pave the way for early interventions and personalized treatment of an incurable condition.

13 Feb 2021

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

SARS-CoV-2 genome is three times larger than influenza genome. Both consist of NRA molecules that mutate when replicate.

13 Feb 2021

Genomics

Study illuminates the role of HAND2 gene in timing of human labor

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Researchers use functional test to measure the effect of inherited variants in BRCA2 cancer gene

Scientists describe genetic mechanisms behind mating process of ciliates

Direct cloning method aims to accelerate large-scale discovery of novel natural products

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

Uninherited genetic mutations can cause spina bifida

Trispecific antibody targets cancer cells, natural killer cells

Study of newlyweds suggests a possible genetic link to marriage satisfaction

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Researchers find a way to improve deletion efficiency of new genome-editing tool

People with ADHD and DBDs share genetic variants associated with risky behaviors

Genetic variant inherited from Neanderthals associated with protection against severe COVID-19

Study outlines the reasons to test pediatric cancer patients for inherited genes

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Study highlights the epigenetics of life at high altitudes

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

Male fruit flies win genetic race with rivals in post-mating fertilization game

Scientists identify genes involved in autoimmune Addison's disease

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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